The Complementary Effects Of Matrilins And WARP On Chondrogenesis Through TGF-beta Signaling
Funder
National Health and Medical Research Council
Funding Amount
$327,428.00
Summary
Osteoarthritis (OA), characterized by degeneration of articular cartilage matrix structure, is one of the most common types of arthritis. Although it is known that aging is a leading factor, the exact cause of degeneration of articular cartilage is not well understood. In order to aid the discovery of treatments and diagnostic tools for this joint disease, understanding functional and mechanistic properties of cartilage specific proteins, namely matrilins and WARP, is essential.