Development And Characterization Of Gallbladder Epithelial Cells
Funder
National Health and Medical Research Council
Funding Amount
$729,227.00
Summary
Death of insulin-producing cells is a common feature of type 1 and type 2 diabetes, affecting over a million Australians. Although transplantation of cadaveric human islets offers cure, lack of donor islets is a major limitations. An alternative is to find other sources of insulin-producing cells. We are the first to demonstrate that insulin-producing cells are naturally found in human gallbladder. This research proposal will involve detailed characterization of human gallbladder-derived insulin ....Death of insulin-producing cells is a common feature of type 1 and type 2 diabetes, affecting over a million Australians. Although transplantation of cadaveric human islets offers cure, lack of donor islets is a major limitations. An alternative is to find other sources of insulin-producing cells. We are the first to demonstrate that insulin-producing cells are naturally found in human gallbladder. This research proposal will involve detailed characterization of human gallbladder-derived insulin-producing cells.Read moreRead less