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Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0775676
Funder
Australian Research Council
Funding Amount
$290,000.00
Summary
An X-ray Diffraction Facility for Molecular Structure Determination. Characterisation of new chemical compounds demands proof of molecular structure. Whether for the identification of a new drug candidate, a material with novel properties or in the exploration of previously unknown types of compounds, X-ray crystallography is the definitive technique for this purpose. This proposal is for an X-ray diffractometer that will significantly enhance the capabilities of all synthetic and natural produc ....An X-ray Diffraction Facility for Molecular Structure Determination. Characterisation of new chemical compounds demands proof of molecular structure. Whether for the identification of a new drug candidate, a material with novel properties or in the exploration of previously unknown types of compounds, X-ray crystallography is the definitive technique for this purpose. This proposal is for an X-ray diffractometer that will significantly enhance the capabilities of all synthetic and natural products chemistry research programs undertaken at the Universities of Queensland and Newcastle, all currently in receipt of ARC funding. This research is aligned with the ARC National Research Priorities, of Promoting and Maintaining Good Health and Frontier Technologies for Building and Transforming Australian Industries.Read moreRead less
Exploring new roles for phosphorus radicals in health, environment, and technology. Several practical outcomes will arise from this project. Information on processes that contribute to genetic disease and cancer will be derived through studies of the role of phosphorus radicals in DNA damage. Processes that lead to the degradation of natural and synthetic materials in the environment will be explored. Clean reactions will be developed for the fabrication of advanced materials (e.g. pharmaceutica ....Exploring new roles for phosphorus radicals in health, environment, and technology. Several practical outcomes will arise from this project. Information on processes that contribute to genetic disease and cancer will be derived through studies of the role of phosphorus radicals in DNA damage. Processes that lead to the degradation of natural and synthetic materials in the environment will be explored. Clean reactions will be developed for the fabrication of advanced materials (e.g. pharmaceuticals). These innovations will expand Australia's international profile in a growing research area. The project will also address three of Australia's National Research Priorities, contribute to the training of researchers in Free Radical Chemistry, and initiate research collaborations with institutions in France and the USA.Read moreRead less
Improving explosive emulsions by understanding surfactant interactions. This project will design new surfactants that will lead to more cost effective, stable and reliable explosive emulsions. The pressure required to force dispersed phase droplets to coalesce will be measured both directly and by osmotic stress. These parameters have not previously been measured for an inverse emulsion system. The measurements made will be correlated to the structure of the stabilising surfactant enabling new a ....Improving explosive emulsions by understanding surfactant interactions. This project will design new surfactants that will lead to more cost effective, stable and reliable explosive emulsions. The pressure required to force dispersed phase droplets to coalesce will be measured both directly and by osmotic stress. These parameters have not previously been measured for an inverse emulsion system. The measurements made will be correlated to the structure of the stabilising surfactant enabling new and more effective surfactants to be designed.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE210100100
Funder
Australian Research Council
Funding Amount
$975,934.00
Summary
Multifunctional Platform for Chemical Manufacturing and Energy Materials. We aim to establish the first platform in Australia for the continuous production and in-situ characterisation of molecules and nanomaterials. This project expects to generate new knowledge in the area of functional materials using an interdisciplinary approach. The expected outcomes will be a unique analytical capability for rapid screening of synthetic and operational parameters, and unprecedented fundamental insight int ....Multifunctional Platform for Chemical Manufacturing and Energy Materials. We aim to establish the first platform in Australia for the continuous production and in-situ characterisation of molecules and nanomaterials. This project expects to generate new knowledge in the area of functional materials using an interdisciplinary approach. The expected outcomes will be a unique analytical capability for rapid screening of synthetic and operational parameters, and unprecedented fundamental insight into chemical reactions to inform the design and development of sustainable chemical processes. This proposal will provide significant benefits to cutting-edge research in catalysis, polymer engineering, separation science, CO2 capture and organic synthesis, to positively impact on the energy-manufacturing-environment nexus.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0668439
Funder
Australian Research Council
Funding Amount
$730,000.00
Summary
Elemental and Structural Analysis Facility Comprising a FTICR Mass Spectrometer and a CHNS Analyser. The determination of molecular structure is important in many fields of chemistry, biochemistry and material science. Without such determinations much chemical research would be viewed as incomplete and rendered unpatentable as well as unpublishable. The two state-of-the-art instruments to be purchased will improve the ability of a wide cross-section of researchers to rapidly characterize compoun ....Elemental and Structural Analysis Facility Comprising a FTICR Mass Spectrometer and a CHNS Analyser. The determination of molecular structure is important in many fields of chemistry, biochemistry and material science. Without such determinations much chemical research would be viewed as incomplete and rendered unpatentable as well as unpublishable. The two state-of-the-art instruments to be purchased will improve the ability of a wide cross-section of researchers to rapidly characterize compounds important in fields as varied as medicinal chemistry, material science and geosciences. All types of chemical research, from fundamental to applied, will benefit from these instruments with clear and positive implications regarding societal impact.Read moreRead less
Sustainable surfactants from Australian oilseeds. This project aims to develop a new generation of sustainable surfactants utilising Australian-grown oilseed feedstocks. These molecules are designed to replace current materials made from petroleum and palm oil, to fulfil a key role as the next generation of bio-resourced detergents and emulsifiers. The work seek to develop a library of new molecules to better understand the relationship between molecular structure and performance, through cuttin ....Sustainable surfactants from Australian oilseeds. This project aims to develop a new generation of sustainable surfactants utilising Australian-grown oilseed feedstocks. These molecules are designed to replace current materials made from petroleum and palm oil, to fulfil a key role as the next generation of bio-resourced detergents and emulsifiers. The work seek to develop a library of new molecules to better understand the relationship between molecular structure and performance, through cutting edge lab testing and utilising national infrastructure, guiding the use of new components in formulating new products. It is anticipated that the surfactants generated will find uses in household cleaning and personal care products, providing high value chemicals from key Australian crops.Read moreRead less
The Development of Chemopropulsion-based Fluidic Transport Systems. The controlled transport of chemical species in fluidic systems is essential to the functioning of living systems. Emulating cellular transport processes in synthetic fluidic systems, so as to allow the controlled transport of reagents or products from one site to another, has the potential to add revolutionary capabilities to fluidic platforms. This project will explore the potential and limits of chemopropulsion and its use as ....The Development of Chemopropulsion-based Fluidic Transport Systems. The controlled transport of chemical species in fluidic systems is essential to the functioning of living systems. Emulating cellular transport processes in synthetic fluidic systems, so as to allow the controlled transport of reagents or products from one site to another, has the potential to add revolutionary capabilities to fluidic platforms. This project will explore the potential and limits of chemopropulsion and its use as a driving mechanism for cargo-carrying vehicles in fluids. The resulting fluidic transport systems could be used to transport medicine in the human body, act as chemical messengers for signal transduction in sensing or other systems or move cargo around microfluidic devices.Read moreRead less
Bubble Stabilization and Density Control in Self-Supporting Explosive Emulsions. The mining industry in Australia employs about 70,000 people and has a total sales and service income of about $55B. Most mining outputs are commodities and a reduction in cost is the primary method of increasing market share. DNAP is a major supplier of explosive services to mines that produce coal, iron ore and gold for export. The work in this project will lead to more efficient explosives emulsions and allow mi ....Bubble Stabilization and Density Control in Self-Supporting Explosive Emulsions. The mining industry in Australia employs about 70,000 people and has a total sales and service income of about $55B. Most mining outputs are commodities and a reduction in cost is the primary method of increasing market share. DNAP is a major supplier of explosive services to mines that produce coal, iron ore and gold for export. The work in this project will lead to more efficient explosives emulsions and allow mining tolower total cost per unit sold. Such improvements in mining efficiencies will have a direct impact of the selling price of the product. Increased export earnings and a greater number of people employed in the industry would be direct results of the successful completion of the work proposed.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE130100057
Funder
Australian Research Council
Funding Amount
$200,000.00
Summary
A diffractometer for small molecule structural elucidation by crystallographic analysis. X-ray diffractometry provides an unambiguous means of identifying the three-dimensional spatial arrangement of atoms within molecules affording important insights into the origins of chemical properties. A modern diffractometer will provide information to help develop new functional materials, therapeutic agents and environmentally sustainable processes.
Bespoke rylene diimides for fundamental and applied photophysics. This project aims to develop and apply bespoke fluorescent molecular systems based on rylene diimide. Fluorescence provides a tuneable, exquisitely sensitive readout allowing detailed investigation and application down to the level of single molecules. This project will use fluorescence to study chemical reactions and energy transfer phenomena, design tools and methodologies for microscopy (including emerging super-resolution tech ....Bespoke rylene diimides for fundamental and applied photophysics. This project aims to develop and apply bespoke fluorescent molecular systems based on rylene diimide. Fluorescence provides a tuneable, exquisitely sensitive readout allowing detailed investigation and application down to the level of single molecules. This project will use fluorescence to study chemical reactions and energy transfer phenomena, design tools and methodologies for microscopy (including emerging super-resolution techniques), and develop 'designed for purpose' systems for a range of applications. The knowledge gained and proofs-of-principle established are expected to influence fields as diverse as energy storage and transduction, imaging and diagnostics and chemical reactions and catalysis.Read moreRead less