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Chemical listening devices: Novel sensors targeting the clandestine manufacture and transport of illicit drugs and explosives. There can be no doubt that protecting Australia's borders from the dual threats of terrorism and illicit drugs is of paramount importance to continuation of our well-being and way of life. Our chemical sensors are simple hand-held or remote chemical listening sensors, which will have the ability to sense the presence of characteristic chemical vapours associated with exp ....Chemical listening devices: Novel sensors targeting the clandestine manufacture and transport of illicit drugs and explosives. There can be no doubt that protecting Australia's borders from the dual threats of terrorism and illicit drugs is of paramount importance to continuation of our well-being and way of life. Our chemical sensors are simple hand-held or remote chemical listening sensors, which will have the ability to sense the presence of characteristic chemical vapours associated with explosives and illicit drugs. The simplicity and low cost of the chemical listening allows for installation at key locations -e.g. transport hubs, shipping containers, airports etc as well as placement within clandestine drug laboratories.Read moreRead less
The Synthesis and Analysis of Certain Explosives and Illicit Drugs for Improved Forensic Detection. There is an increasing demand within law enforcement agencies, worldwide, for selective and sensitive methods for the determination of illicit substances. Over the last decade Deakin University chemists have played a major role in establishing the utility of chemiluminescent reactions for the determination of a variety of pharmaceutical opiates in process streams. This project seeks to build upon ....The Synthesis and Analysis of Certain Explosives and Illicit Drugs for Improved Forensic Detection. There is an increasing demand within law enforcement agencies, worldwide, for selective and sensitive methods for the determination of illicit substances. Over the last decade Deakin University chemists have played a major role in establishing the utility of chemiluminescent reactions for the determination of a variety of pharmaceutical opiates in process streams. This project seeks to build upon these successes, in order to develop innovative analytical strategies for forensic detection of certain illicit drugs and explosives. The results of this research have the potential to revolutionise key aspects of forensic analysis.Read moreRead less
Polymer technologies for oil spill remediation and slow-release fertilisers. This project aims to evaluate a patented sulfur polymer in commercial oil spill remediation and slow-release fertilisers. Key objectives are to determine how the polymer degrades, assess the effectiveness of the polymer in oil spill sorption in different contexts, and investigate the polymer as a matrix for slow-release fertilisers. The project expects to generate new approaches to sustainable remediation and crop produ ....Polymer technologies for oil spill remediation and slow-release fertilisers. This project aims to evaluate a patented sulfur polymer in commercial oil spill remediation and slow-release fertilisers. Key objectives are to determine how the polymer degrades, assess the effectiveness of the polymer in oil spill sorption in different contexts, and investigate the polymer as a matrix for slow-release fertilisers. The project expects to generate new approaches to sustainable remediation and crop production. Expected outcomes include new knowledge about the biodegradation of the polymer, new methods for deploying the polymer in oil spill cleanup, and new fertilisers that prevent nutrient waste and runoff. Significant benefits are expected for the environment, as well as economic benefits to the manufacturer and end-users.Read moreRead less
AI Assisted Continuous Flow Electrochemistry for Pharmaceutical Manufacture. This project aims to develop new chemical manufacturing processes for pharmaceutical products. In collaboration with Sun Pharma, it will tackle the challenge of replacing expensive and toxic chemicals in industrial reactions, to lower cost of manufacturing and improve its sustainability profile. Central to the realisation of this ambition is the use of electrocatalysis, machine learning and implementation of advanced co ....AI Assisted Continuous Flow Electrochemistry for Pharmaceutical Manufacture. This project aims to develop new chemical manufacturing processes for pharmaceutical products. In collaboration with Sun Pharma, it will tackle the challenge of replacing expensive and toxic chemicals in industrial reactions, to lower cost of manufacturing and improve its sustainability profile. Central to the realisation of this ambition is the use of electrocatalysis, machine learning and implementation of advanced continuous flow methods. These electricity- and technology-driven reactions will develop new strategies for the generation of important classes of molecules relevant to the Australia’s pharmaceutical sector, as well as their manufacture at industrially relevant scales.Read moreRead less
CHARACTERISATION OF NOVEL BIOACTIVES FROM AUSTRALIAN HONEY WITH THERAPEUTIC POTENTIAL. Honey from specific Australian flowering plants has been identified that contain significant therapeutic properties in wound healing and other treatments. The research project proposed will identify and fully characterise the bioactive components of selected Australian honey (Medihoney) with antibiotic and growth promoting activites. These aims will be supported by high resolution mass spectrometry interfaced ....CHARACTERISATION OF NOVEL BIOACTIVES FROM AUSTRALIAN HONEY WITH THERAPEUTIC POTENTIAL. Honey from specific Australian flowering plants has been identified that contain significant therapeutic properties in wound healing and other treatments. The research project proposed will identify and fully characterise the bioactive components of selected Australian honey (Medihoney) with antibiotic and growth promoting activites. These aims will be supported by high resolution mass spectrometry interfaced with HPLC and or affinity chip surfaces, 750 MHz NMR analysis and a range of relevant bioassays on specific organisms and cell lines. These outcomes will not only enhance the value of current honey-based products but have the potential to identify new therapeutic lead molecules.Read moreRead less
Controlling light-harvesting with complex perylene arrays. This project aims to artificially mimic photosynthesis. A new class of dye coloured plastics will create a platform technology that could have many applications including enhanced biodiesel production from algae and 'smart' building materials enhancing electricity production from solar cells.
Praziquantel: a unique pharmaceutical challenge. Generating effective and affordable drugs for the treatment of tropical diseases is a huge public health challenge. We will pioneer an open source approach to collaborative research in drug discovery. We aim to discover an inexpensive route to an important pharmaceutical so that it can be greatly improved and distributed to the affected populations for a realistic price. Success in this project will improve the lives of millions of sufferers of th ....Praziquantel: a unique pharmaceutical challenge. Generating effective and affordable drugs for the treatment of tropical diseases is a huge public health challenge. We will pioneer an open source approach to collaborative research in drug discovery. We aim to discover an inexpensive route to an important pharmaceutical so that it can be greatly improved and distributed to the affected populations for a realistic price. Success in this project will improve the lives of millions of sufferers of this disease, and demonstrate a new way of doing research on drugs for related diseases such as malaria. Read moreRead less
Improving explosive emulsions by understanding surfactant interactions. This project will design new surfactants that will lead to more cost effective, stable and reliable explosive emulsions. The pressure required to force dispersed phase droplets to coalesce will be measured both directly and by osmotic stress. These parameters have not previously been measured for an inverse emulsion system. The measurements made will be correlated to the structure of the stabilising surfactant enabling new a ....Improving explosive emulsions by understanding surfactant interactions. This project will design new surfactants that will lead to more cost effective, stable and reliable explosive emulsions. The pressure required to force dispersed phase droplets to coalesce will be measured both directly and by osmotic stress. These parameters have not previously been measured for an inverse emulsion system. The measurements made will be correlated to the structure of the stabilising surfactant enabling new and more effective surfactants to be designed.Read moreRead less
Selective Detection and Removal of Contaminants That Have an Adverse Impact on Australian Raw Sugar Quality. Sugar is Australia's 2nd largest agricultural crop with 80-85% exported earning $2 billion in export revenue. Whilst Australia is arguably the most reliable supplier of premium raw sugar the implementation of improved processing technologies by rivals has (and without appropriate research strategies will continue to) eroded some of the long-held Australian advantages.
Our innovative a ....Selective Detection and Removal of Contaminants That Have an Adverse Impact on Australian Raw Sugar Quality. Sugar is Australia's 2nd largest agricultural crop with 80-85% exported earning $2 billion in export revenue. Whilst Australia is arguably the most reliable supplier of premium raw sugar the implementation of improved processing technologies by rivals has (and without appropriate research strategies will continue to) eroded some of the long-held Australian advantages.
Our innovative approaches will improve raw sugar quality, measurement methods, and allow new product development (value adding), enabling Australia to maintain its? world leading position. Importantly, our technologies enable improvements of specific quality issues (and potentially as yet unidentified issues), further differentiating the Australian product in the international marketplace.
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Study the Utility of Novel Drug Polymer Conjugates. The products likely to arise from the technology described in this proposal could have application in medical, veterinary and agricultural industries. It offers the potential to treat diseases that are at present poorly treated by enabling delivery direct to the diseased organ (e.g. eye - bacterial endophthalmitis). Completion of the project will also assist a fledgling biotech company transition to a development company with a multiple produ ....Study the Utility of Novel Drug Polymer Conjugates. The products likely to arise from the technology described in this proposal could have application in medical, veterinary and agricultural industries. It offers the potential to treat diseases that are at present poorly treated by enabling delivery direct to the diseased organ (e.g. eye - bacterial endophthalmitis). Completion of the project will also assist a fledgling biotech company transition to a development company with a multiple product portfolio, which will have a direct economic benefit to Australia both in terms of potential export earnings and as an employer highly skilled staff. The project will also provide research training and career opportunities for developing Australian based researchers.Read moreRead less