Evaluation Of Future Cervical Cancer Prevention Strategies In Australia
Funder
National Health and Medical Research Council
Funding Amount
$401,361.00
Summary
The overall aim of the project is to use simulation modelling to perform a detailed epidemiologic and economic evaluation of the role of primary HPV DNA testing in Australia in the context of HPV vaccination. The project involves a collaboration with investigators at the National Cancer Institute USA, to analyse data from large studies conducted around the world and to build an accurate simulation of HPV infection and the development of cervical cancer.
Population Health Modelling, With Applicationsto Asbestos-related Diseases, Cervical Cancer And Prostate Cancer
Funder
National Health and Medical Research Council
Funding Amount
$380,558.00
Summary
Population health modelling can be used to understand complex systems, through bringing together diverse data sources to answer questions of public health importance. We will apply modelling techniques to three public health areas, including: the effects of HPV testing on cervical cancer screening; the impact of the rapid uptake of PSA screening on prostate cancer incidence and mortality; and projections of the incidence of asbestos-related diseases.
Novel Point-of-care Screening And Treatment Interventions To Improve Pregnancy Outcomes And To Prevent Cervical Cancer In High-burden, Low-income Settings
Funder
National Health and Medical Research Council
Funding Amount
$470,144.00
Summary
I lead newly-funded research grants worth nearly $10 million to conduct novel intervention trials in sexual and reproductive health. These projects build on the extensive collaborations and the robust nationwide network of clinical field sites that I have established in Papua New Guinea during the past five years. My research will lead to improved maternal and neonatal health outcomes, and prevent premature deaths due to cervical cancer, in high-burden, low-income settings worldwide.
Population Genetics And Functional Genomics Approaches To Improve Outcomes For Patients With Colorectal Cancer
Funder
National Health and Medical Research Council
Funding Amount
$466,492.00
Summary
Colorectal cancer (CRC) is the third leading cause of cancer related death in Australia, and the 5-year survival rate for metastatic disease remains below 10%. Over the next 4 years, my translational research program will focus on improving patient outcomes in four ways: Discovery of inherited variants affecting CRC risk and progression, tumour molecular classification, discovery of markers for prognosis and drug response, and elucidation of the molecular mechanisms driving CRC development.
Improving Cancer Outcomes In Under-studied Cancers By Understanding Their Risk Factors And Patterns Of Cancer Care.
Funder
National Health and Medical Research Council
Funding Amount
$421,747.00
Summary
Cancer is the second leading cause of disease burden in Australia. Much can be done to reduce this burden through effective cancer prevention and ensuring all patients receive optimal evidence-based care. This research focuses on thyroid, kidney and ovarian cancer and aims to increase knowledge of these cancers’ causes and to investigate variation in patient care and its impact on outcomes. Ultimately the objective of the work is to decrease Australia’s cancer burden.