Control of developmental switches by importin 5. Aims: This project will study a key molecular switch called IPO5, a protein that is required for cells and organs to form and function normally, and it will reveal how it works.
Significance: These experiments will provide the first complete description of how this molecular switch controls the behaviour of a cell across its lifespan. IPO5 is highly conserved, so these studies will be relevant to a wide range of animals.
Expected Outcomes: This k ....Control of developmental switches by importin 5. Aims: This project will study a key molecular switch called IPO5, a protein that is required for cells and organs to form and function normally, and it will reveal how it works.
Significance: These experiments will provide the first complete description of how this molecular switch controls the behaviour of a cell across its lifespan. IPO5 is highly conserved, so these studies will be relevant to a wide range of animals.
Expected Outcomes: This knowledge will reveal how IPO5 controls formation of sperm by revealing what other proteins it binds to and how this affects cell signaling and responses to the environment.
Benefits: This will provide information about potential interventions to control fertility or to repair abnormal cells.
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Addressing Misinformation with Media Literacy through Cultural Institutions. Misinformation can harm democratic processes, social cohesion and public health outcomes. Media literacy prepares citizens for misinformation by developing critical analysis abilities. This project partners with Australian public cultural institutions to increase adult media literacy. Through an action-based, mixed methods approach, the project investigates adults’ experiences with online misinformation and assesses the ....Addressing Misinformation with Media Literacy through Cultural Institutions. Misinformation can harm democratic processes, social cohesion and public health outcomes. Media literacy prepares citizens for misinformation by developing critical analysis abilities. This project partners with Australian public cultural institutions to increase adult media literacy. Through an action-based, mixed methods approach, the project investigates adults’ experiences with online misinformation and assesses their ability to identify and challenge it. Research findings will inform the design and evaluation of targeted evidence-based media literacy training and resources that will be shared across broadcast media, physical spaces and online. Through these initiatives Australians will be better equipped to combat misinformation.Read moreRead less
Museum Digital Social Futures. This project aims to understand and transform the digital experience of museum audiences post COVID-19 through collaborating with ACMI who pioneered digital curation methods through a Living Lab model. This project will generate new methods for engaging diverse audiences across social and digital worlds in domestic and public spaces through codesigning with national museum peak body, AGaMA, stakeholders. Expected outcomes include resources (i.e. toolkits for implem ....Museum Digital Social Futures. This project aims to understand and transform the digital experience of museum audiences post COVID-19 through collaborating with ACMI who pioneered digital curation methods through a Living Lab model. This project will generate new methods for engaging diverse audiences across social and digital worlds in domestic and public spaces through codesigning with national museum peak body, AGaMA, stakeholders. Expected outcomes include resources (i.e. toolkits for implementation), online repository (website) and symposium for knowledge sharing and transferring of learnings. This should provide significant benefits to the museums sector including digital innovation for social inclusion strategies and resources.
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Young Australians and the promotion of alcohol on social media. This project aims to determine how young people engage with alcohol and nightlife marketing on social media platforms like Facebook, Instagram, and Snapchat. Companies now leverage the power of social media to create advertisements that are made and shared by young people, targeted to them in particular times, places and contexts, and are thus difficult to monitor and regulate. The project will use computational, big social data app ....Young Australians and the promotion of alcohol on social media. This project aims to determine how young people engage with alcohol and nightlife marketing on social media platforms like Facebook, Instagram, and Snapchat. Companies now leverage the power of social media to create advertisements that are made and shared by young people, targeted to them in particular times, places and contexts, and are thus difficult to monitor and regulate. The project will use computational, big social data approaches and youth informants to assess the pervasiveness of branding on social media and how it shapes youth cultures. This work will extend media and cultural studies and support the development of effective monitoring and regulation of online marketing in general, with a particular focus on alcohol.Read moreRead less
When Your Face is Your ID: Public Responses to Automated Facial Recognition. This project would explore public attitudes toward the use of facial recognition technology in public and commercial spaces, schools, and workplaces with a national survey, focus group interviews, and four case studies. The project aims to generate new knowledge about public attitudes through a multi-method interdisciplinary approach that anticipates the future of the technology by studying its use in China. Expected ou ....When Your Face is Your ID: Public Responses to Automated Facial Recognition. This project would explore public attitudes toward the use of facial recognition technology in public and commercial spaces, schools, and workplaces with a national survey, focus group interviews, and four case studies. The project aims to generate new knowledge about public attitudes through a multi-method interdisciplinary approach that anticipates the future of the technology by studying its use in China. Expected outcomes include public reports on the survey and case studies, seven academic journal articles, and a book. The research would provide significant benefits by contributing new knowledge about how to implement the technology in accordance with Australian commitments to civil rights, ethics and democratic values.
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Linkage Infrastructure, Equipment And Facilities - Grant ID: LE210100046
Funder
Australian Research Council
Funding Amount
$289,381.00
Summary
A fast fluorescence lifetime imaging microscope to track protein dynamics. This project aims to establish a fast fluorescence lifetime imaging microscope that can track the intracellular journey of a protein throughout the entire structural framework of a living cell. By coupling single particle tracking technology with a cutting-edge fluorescence lifetime camera, this one-of-a-kind microscope will enable protein mobility and interaction to be spatially mapped with unprecedented temporal resolut ....A fast fluorescence lifetime imaging microscope to track protein dynamics. This project aims to establish a fast fluorescence lifetime imaging microscope that can track the intracellular journey of a protein throughout the entire structural framework of a living cell. By coupling single particle tracking technology with a cutting-edge fluorescence lifetime camera, this one-of-a-kind microscope will enable protein mobility and interaction to be spatially mapped with unprecedented temporal resolution. The benefit of this technology is that it will enable scientists in Australia to image, for the first time, the biophysical mechanism by which a protein navigates intracellular architecture to regulate a complex biological function at the single molecule level.Read moreRead less
Modelling human brain development with stem cells and biomaterials. With limited resources to directly study and advance our understanding of human neural development, this
proposal will establish models of 4 key stages. Employing innovative, interdisciplinary approaches, biomaterials will be fabricated to provide structural and chemical support for human stem cells during: (i) neural induction, (ii) specification into neuronal progenitor subpopulations, (iii) neuronal maturation and integration ....Modelling human brain development with stem cells and biomaterials. With limited resources to directly study and advance our understanding of human neural development, this
proposal will establish models of 4 key stages. Employing innovative, interdisciplinary approaches, biomaterials will be fabricated to provide structural and chemical support for human stem cells during: (i) neural induction, (ii) specification into neuronal progenitor subpopulations, (iii) neuronal maturation and integration into complex neural networks as well as, (iv) the organisation of neurons into larger 3-dimensional brain structures, namely folding of the human cortex. Further, biomaterials developed here have commercialisation potential, targeted at standardizing the culturing of human stem cells to defined neural populations.
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Exploring Botanic Gardens Herbarium's value, via Environmental Aesthetics. . The project aims to aesthetically redefine engagement with the plant collection at Royal Botanic Gardens Herbarium (RBG) Sydney and to communicate its artistic, cultural and heritage value to the public through a Public Program of creative arts case studies. It's expected that new insights will arise from an environmental art methodology utilising the digitisation of the Herbarium specimens, so that audiences can intera ....Exploring Botanic Gardens Herbarium's value, via Environmental Aesthetics. . The project aims to aesthetically redefine engagement with the plant collection at Royal Botanic Gardens Herbarium (RBG) Sydney and to communicate its artistic, cultural and heritage value to the public through a Public Program of creative arts case studies. It's expected that new insights will arise from an environmental art methodology utilising the digitisation of the Herbarium specimens, so that audiences can interactively experience the plant archive through narratives that activate plants as underpinning ecosystems. Benefits to partners RBG, Bundanon Trust and Open Humanities Press will include the digital expansion of audience engagement with the Herbarium at RBG and Mt Annan and communication of collection’s significance.Read moreRead less