Understanding glycopolymer interactions with the extracellular matrix. This project aims to advance knowledge of the biochemical and biophysical structure of the endothelial glycocalyx, a dynamic cell surface extracellular matrix rich in proteoglycans and glycosaminoglycans. It will be the first to explore how charged glycopolymers interact with this dynamic interface with the goal to develop a model of the glycocalyx lifecycle. This project is expected to enable the transfer of skills, knowledg ....Understanding glycopolymer interactions with the extracellular matrix. This project aims to advance knowledge of the biochemical and biophysical structure of the endothelial glycocalyx, a dynamic cell surface extracellular matrix rich in proteoglycans and glycosaminoglycans. It will be the first to explore how charged glycopolymers interact with this dynamic interface with the goal to develop a model of the glycocalyx lifecycle. This project is expected to enable the transfer of skills, knowledge and ideas as well as advanced research and industrial training for young scientists. Knowledge derived from this project is expected to enable future innovation in molecules with tailored interactions with the glycocalyx with significant benefits for researchers, manufacturers and end users. Read moreRead less
Understanding platinum dissolution in biomedical stimulating electrodes. Platinum is the main material used in electrodes for neurostimulators like the cochlear implant. Platinum electrodes can experience dissolution during implantation, which can impact on their function. The mechanisms governing this dissolution process are complex and still not fully understood. This research aims to understand the chemical, electrical and biological factors that impact on platinum dissolution in electrodes. ....Understanding platinum dissolution in biomedical stimulating electrodes. Platinum is the main material used in electrodes for neurostimulators like the cochlear implant. Platinum electrodes can experience dissolution during implantation, which can impact on their function. The mechanisms governing this dissolution process are complex and still not fully understood. This research aims to understand the chemical, electrical and biological factors that impact on platinum dissolution in electrodes. It will also develop new 3D models to simulate conditions in the human body for more rapid testing of electrodes. The new knowledge generated will improve the accuracy of predictions of platinum dissolution, develop new approaches for minimising dissolution, and contribute to reducing need for animal experimentation.Read moreRead less
Polymer technologies for oil spill remediation and slow-release fertilisers. This project aims to evaluate a patented sulfur polymer in commercial oil spill remediation and slow-release fertilisers. Key objectives are to determine how the polymer degrades, assess the effectiveness of the polymer in oil spill sorption in different contexts, and investigate the polymer as a matrix for slow-release fertilisers. The project expects to generate new approaches to sustainable remediation and crop produ ....Polymer technologies for oil spill remediation and slow-release fertilisers. This project aims to evaluate a patented sulfur polymer in commercial oil spill remediation and slow-release fertilisers. Key objectives are to determine how the polymer degrades, assess the effectiveness of the polymer in oil spill sorption in different contexts, and investigate the polymer as a matrix for slow-release fertilisers. The project expects to generate new approaches to sustainable remediation and crop production. Expected outcomes include new knowledge about the biodegradation of the polymer, new methods for deploying the polymer in oil spill cleanup, and new fertilisers that prevent nutrient waste and runoff. Significant benefits are expected for the environment, as well as economic benefits to the manufacturer and end-users.Read moreRead less
AI Assisted Continuous Flow Electrochemistry for Pharmaceutical Manufacture. This project aims to develop new chemical manufacturing processes for pharmaceutical products. In collaboration with Sun Pharma, it will tackle the challenge of replacing expensive and toxic chemicals in industrial reactions, to lower cost of manufacturing and improve its sustainability profile. Central to the realisation of this ambition is the use of electrocatalysis, machine learning and implementation of advanced co ....AI Assisted Continuous Flow Electrochemistry for Pharmaceutical Manufacture. This project aims to develop new chemical manufacturing processes for pharmaceutical products. In collaboration with Sun Pharma, it will tackle the challenge of replacing expensive and toxic chemicals in industrial reactions, to lower cost of manufacturing and improve its sustainability profile. Central to the realisation of this ambition is the use of electrocatalysis, machine learning and implementation of advanced continuous flow methods. These electricity- and technology-driven reactions will develop new strategies for the generation of important classes of molecules relevant to the Australia’s pharmaceutical sector, as well as their manufacture at industrially relevant scales.Read moreRead less
New technologies for e-waste recycling. This project aims to provide commercially viable methods for recycling electronic waste (e-waste), with a focus on plastic recycling and precious metal recovery from circuit boards. This project expects to generate new knowledge in the separation and recovery of gold, silver, and palladium using novel leach reagents and sorbents. Additionally, new techniques will be evaluated for converting e-waste plastic into construction materials. Expected outcomes of ....New technologies for e-waste recycling. This project aims to provide commercially viable methods for recycling electronic waste (e-waste), with a focus on plastic recycling and precious metal recovery from circuit boards. This project expects to generate new knowledge in the separation and recovery of gold, silver, and palladium using novel leach reagents and sorbents. Additionally, new techniques will be evaluated for converting e-waste plastic into construction materials. Expected outcomes of this project include new capabilities for Australia's e-waste recycling industry, as the majority of circuit board waste is shipped overseas. This should provide significant economic benefits such as the recovery of valuable metals and the development of novel construction materials.Read moreRead less
Polymer nanofibres for advanced paint formulations. Surface coatings seal, strengthen, and decorate the majority of surfaces in the building industry—a $72 billion market. Despite their importance, advances in paint science have only been incremental and a truly robust and water resistant paint coating has yet to be developed. Dulux Group Australia and the University of Sydney will use polymer nanofibres as additives to radically redesign architectural coatings, with the goal to drastically incr ....Polymer nanofibres for advanced paint formulations. Surface coatings seal, strengthen, and decorate the majority of surfaces in the building industry—a $72 billion market. Despite their importance, advances in paint science have only been incremental and a truly robust and water resistant paint coating has yet to be developed. Dulux Group Australia and the University of Sydney will use polymer nanofibres as additives to radically redesign architectural coatings, with the goal to drastically increase their durability. The partnership will bring a technological breakthrough that will lead to less disruption for the environment, and important economic and technological benefits for Australia.Read moreRead less
Hierarchically porous polymer monoliths for separation science. Understanding the molecular composition of biomarkers involved in cell-cell communication and the fate of nanoparticles in the environment is critical to improve our understanding of diseases and environmental processes. This project will develop a new approach for the design of separation media that will greatly improve the efficiency of techniques used to analyse these complex samples. The separation media will consist of a polyme ....Hierarchically porous polymer monoliths for separation science. Understanding the molecular composition of biomarkers involved in cell-cell communication and the fate of nanoparticles in the environment is critical to improve our understanding of diseases and environmental processes. This project will develop a new approach for the design of separation media that will greatly improve the efficiency of techniques used to analyse these complex samples. The separation media will consist of a polymer containing large flow-through pores as well as well-defined mesopores. This dual porous skeleton will allow for the size-based separation of biomarkers and nanoparticles. The new separation media will enable the development of new technologies with applications in areas such medicine and environmental science.Read moreRead less
Advanced framework materials for hydrogen storage applications. This project aims to develop new molecular materials capable of the highly efficient storage of hydrogen gas. Through an innovative interdisciplinary approach that targets the synthesis and detailed characterisation of two classes of molecular material this project expects to generate step-change advances in the understanding of how hydrogen gas uptake relates to the chemical and physical attributes of porous molecular systems. Sign ....Advanced framework materials for hydrogen storage applications. This project aims to develop new molecular materials capable of the highly efficient storage of hydrogen gas. Through an innovative interdisciplinary approach that targets the synthesis and detailed characterisation of two classes of molecular material this project expects to generate step-change advances in the understanding of how hydrogen gas uptake relates to the chemical and physical attributes of porous molecular systems. Significant anticipated outcomes and benefits include the development of new material design approaches that optimise performance across a diverse parameter space, and the generation of advanced new materials worthy of commercial development, spanning small scale mobile to large scale stationary storage applications.Read moreRead less
Sustainable surfactants from Australian oilseeds. This project aims to develop a new generation of sustainable surfactants utilising Australian-grown oilseed feedstocks. These molecules are designed to replace current materials made from petroleum and palm oil, to fulfil a key role as the next generation of bio-resourced detergents and emulsifiers. The work seek to develop a library of new molecules to better understand the relationship between molecular structure and performance, through cuttin ....Sustainable surfactants from Australian oilseeds. This project aims to develop a new generation of sustainable surfactants utilising Australian-grown oilseed feedstocks. These molecules are designed to replace current materials made from petroleum and palm oil, to fulfil a key role as the next generation of bio-resourced detergents and emulsifiers. The work seek to develop a library of new molecules to better understand the relationship between molecular structure and performance, through cutting edge lab testing and utilising national infrastructure, guiding the use of new components in formulating new products. It is anticipated that the surfactants generated will find uses in household cleaning and personal care products, providing high value chemicals from key Australian crops.Read moreRead less
Advanced Fibre Interfaces in Active Water Management Systems. Flooding is a critical issue in Australia, generating considerable economic losses, including by stormwater contamination. The current project will pioneer an integrated solution for stormwater retention, while removing chemical pollutants. In collaboration with the company ROCKWOOL-Lapinus - based on a stonewool fibre platform - we will (i) design fibre coatings based on a versatile and chemically simple deposition process, (ii) inco ....Advanced Fibre Interfaces in Active Water Management Systems. Flooding is a critical issue in Australia, generating considerable economic losses, including by stormwater contamination. The current project will pioneer an integrated solution for stormwater retention, while removing chemical pollutants. In collaboration with the company ROCKWOOL-Lapinus - based on a stonewool fibre platform - we will (i) design fibre coatings based on a versatile and chemically simple deposition process, (ii) incorporate functionalities onto the fibres allowing active stormwater treatment to e.g. retain pollutants or target heavy metals and (iii) investigate these interfaces in-depth by advanced surface and interface characterisation methods to understand the fibre interface properties from nano- to macroscale.Read moreRead less