Assessing the impact of habitat restoration on the rates of recovery of four native fish species using advanced statistical models. This project will develop statistical modelling tools to assess how quickly threatened native fish populations recover following habitat restoration. The outcome of this project will aid in understanding the use of habitat restoration in managing endangered stocks of Murray Cod, Trout Cod, Silver Perch and Golden Perch in the Murray River.
Diagnosing river health using invertebrate traits and DNA barcodes. Diagnosing river health using invertebrate traits and DNA barcodes. This project aims to develop indices that link change in invertebrate communities to specific environmental stressors, and combine these indices with innovative, low cost molecular approaches to species identification to rapidly identify the causes of decline. River health assessment methods, usually based on aquatic invertebrates, identify if rivers are impaire ....Diagnosing river health using invertebrate traits and DNA barcodes. Diagnosing river health using invertebrate traits and DNA barcodes. This project aims to develop indices that link change in invertebrate communities to specific environmental stressors, and combine these indices with innovative, low cost molecular approaches to species identification to rapidly identify the causes of decline. River health assessment methods, usually based on aquatic invertebrates, identify if rivers are impaired but must be developed to identify the causes of decline. The intended outcomes are improved sustainable water resource management within and among states, and improved natural resource policy development.Read moreRead less
Novel Self Assembled Particle Systems as a Key to Next Generation Biosensor Technology. Development and commercialisation of products utilising nanotechnology is crucial to future wealth creation for Australia. The translational research in this proposal will progress innovative concepts in nanotechnology-based biosensors, with potential for substantial improvements in disease diagnosis, leading to more economical and timely therapy. The products that arise from this research will also provide f ....Novel Self Assembled Particle Systems as a Key to Next Generation Biosensor Technology. Development and commercialisation of products utilising nanotechnology is crucial to future wealth creation for Australia. The translational research in this proposal will progress innovative concepts in nanotechnology-based biosensors, with potential for substantial improvements in disease diagnosis, leading to more economical and timely therapy. The products that arise from this research will also provide further employment for Australians, building on Universal Biosensor’s proven record of commercialization in Australia. The project will lead to training of Australian researchers in nanotechnology and in utilization of key Australian science infrastructure including the Australian Synchrotron and the Melbourne Centre for Nanofabrication.Read moreRead less
Interfacial and Structural Changes During Digestion of Milk-like Systems. This project aims to enhance the understanding of the behaviour of milk and milk-like systems during digestion. Utilising new Australian research infrastructure the project aims to unlock the complex behaviour across different types of milk (including human breast milk) and infant formulae, linking how enzymes behave towards fat droplets and the consequences for lipid structuring and nutrient transport. The rational design ....Interfacial and Structural Changes During Digestion of Milk-like Systems. This project aims to enhance the understanding of the behaviour of milk and milk-like systems during digestion. Utilising new Australian research infrastructure the project aims to unlock the complex behaviour across different types of milk (including human breast milk) and infant formulae, linking how enzymes behave towards fat droplets and the consequences for lipid structuring and nutrient transport. The rational design of systems that function much more closely to human milk will enable the development of new products with flow on benefits in human nutrition and increased utilisation of products from our dairy industry.Read moreRead less
Improved biomonitoring of urban freshwater ecosystems using DNA barcodes. This project aims to provide rapid diagnostic detection of environmental change in aquatic ecosystems at reduced cost. Next-generation sequencing (NGS) can transform monitoring of aquatic ecosystems by identifying many species in multiple biological samples. This project aims to use NGS technology to identify macroinvertebrate species as biological indicators in urban freshwater ecosystems to provide more rapid, sensitive ....Improved biomonitoring of urban freshwater ecosystems using DNA barcodes. This project aims to provide rapid diagnostic detection of environmental change in aquatic ecosystems at reduced cost. Next-generation sequencing (NGS) can transform monitoring of aquatic ecosystems by identifying many species in multiple biological samples. This project aims to use NGS technology to identify macroinvertebrate species as biological indicators in urban freshwater ecosystems to provide more rapid, sensitive and cost-effective monitoring compared to traditional methods. The project uses DNA barcodes that identify species to detect species in samples processed with NGS. The project also plans to use previously collected samples to explore species diversity and detect indicator species.Read moreRead less
Hydrogeological drivers and fate of spring flow in a semi-arid setting. In arid and semi-arid climates, aquatic and terrestrial ecosystems often rely on groundwater springs. Spring hydrology depends on complex relationships between underlying aquifers and surface conditions, leading to high uncertainties in understanding aquifer-spring-wetland hydrology, which is critical for spring ecosystem protection and to inform management of relevant groundwater-affecting activities. This project will appl ....Hydrogeological drivers and fate of spring flow in a semi-arid setting. In arid and semi-arid climates, aquatic and terrestrial ecosystems often rely on groundwater springs. Spring hydrology depends on complex relationships between underlying aquifers and surface conditions, leading to high uncertainties in understanding aquifer-spring-wetland hydrology, which is critical for spring ecosystem protection and to inform management of relevant groundwater-affecting activities. This project will apply novel hydrogeophysical and hydrochemical methods, and computer modelling, to investigate the source aquifer of, and fate of discharge from the Doongmabulla Springs Complex (DSC), located in an area of future development. Project results will inform spring vulnerability to development pressures and climate effects.Read moreRead less
Characterisation and Stability of ISCOM Vaccines. ISCOMS® are particles comprising saponin, cholesterol and phospholipids which when mixed with proteins form potent vaccines. When proteins are associated with ISCOMs® a variety of different sized particles with various surface chemistries can be formed. This project aims to understand the physico-chemical mechanisms governing ISCOM® formation. This understanding will allow development of methods for controlling the size, characteristics and long- ....Characterisation and Stability of ISCOM Vaccines. ISCOMS® are particles comprising saponin, cholesterol and phospholipids which when mixed with proteins form potent vaccines. When proteins are associated with ISCOMs® a variety of different sized particles with various surface chemistries can be formed. This project aims to understand the physico-chemical mechanisms governing ISCOM® formation. This understanding will allow development of methods for controlling the size, characteristics and long-term stability of these particles. In addition the size and surface chemistry of the particles will be correlated with their effectiveness as vaccines. Both these outcomes will support the ongoing commercial development of ISCOM®-based vaccines at CSL.Read moreRead less
Can we see the wood for the trees? Effective restoration strategies in rapidly changing subtropical river systems. Addressing the issue of degraded waterways nationally will cost billions of dollars; in southeast Queensland alone it is estimated that it will cost $500 million. Fundamental research is needed to ensure such efforts achieve the desired outcomes. Previous research has shown riverbank erosion is a key stressor for water quality. This project aims to link fluvial disturbance with the ....Can we see the wood for the trees? Effective restoration strategies in rapidly changing subtropical river systems. Addressing the issue of degraded waterways nationally will cost billions of dollars; in southeast Queensland alone it is estimated that it will cost $500 million. Fundamental research is needed to ensure such efforts achieve the desired outcomes. Previous research has shown riverbank erosion is a key stressor for water quality. This project aims to link fluvial disturbance with the capacity for effective riparian restoration in subtropical river systems at a local, reach and whole of catchment scale. The outcome aims to develop decision-support tools and methods for industry partners to invest in catchment-scale restoration activities in order to manage the risks to drinking water quality and aquatic ecosystem health from riverbank erosion.Read moreRead less
Restoring functional links between riparian zones and streams by enhancing structural retention. This project aims to test whether structural retention, whereby plant detritus (logs, bark, leaves) is trapped and retained within river channels, can offset the impacts caused by widespread clearance of vegetation along river banks, a widespread problem in Australia and the world. Theoretically, retention is a major environmental driver of ecosystem change in rivers, but this has rarely been tested, ....Restoring functional links between riparian zones and streams by enhancing structural retention. This project aims to test whether structural retention, whereby plant detritus (logs, bark, leaves) is trapped and retained within river channels, can offset the impacts caused by widespread clearance of vegetation along river banks, a widespread problem in Australia and the world. Theoretically, retention is a major environmental driver of ecosystem change in rivers, but this has rarely been tested, particularly in a restoration context. The aim of this project is to show that increasing retention results in higher species diversity, thus providing managers with a relatively straightforward method for improving the environmental conditions of rivers, while simultaneously testing three hypotheses about rectifying ecosystem degradation caused by human impacts.Read moreRead less
Causes of and Cures for Microbiological Foams in Activated Sludge Wastewater Treatment Plants. Little is known of the true diversity of the bacteria causing foaming in activated sludge systems, or why and how they cause these foams. This application seeks funds for an interdisciplinary approach to address these issues, involving input from microbiologists and surface chemists and physicists. Molecular techniques will be used to determine precisely the foaming bacterial communities and their phys ....Causes of and Cures for Microbiological Foams in Activated Sludge Wastewater Treatment Plants. Little is known of the true diversity of the bacteria causing foaming in activated sludge systems, or why and how they cause these foams. This application seeks funds for an interdisciplinary approach to address these issues, involving input from microbiologists and surface chemists and physicists. Molecular techniques will be used to determine precisely the foaming bacterial communities and their physiology, while their surface chemistry and organisation will be studied to understand the mechanisms involved in foaming with the intention of developing control strategies for this global problem suitable for large scale application.Read moreRead less