Upscaling genetic management of wildlife populations. Earth’s biodiversity is in crisis: many species are threatened with extinction and need our help. Genetic management helps to stop extinctions and promotes the health and continued existence of our wildlife. This project aims to understand how to use genome science to support preservation of four endangered species in changing climates and apply these learnings to help other species to survive and thrive. Anticipated outcomes include innovati ....Upscaling genetic management of wildlife populations. Earth’s biodiversity is in crisis: many species are threatened with extinction and need our help. Genetic management helps to stop extinctions and promotes the health and continued existence of our wildlife. This project aims to understand how to use genome science to support preservation of four endangered species in changing climates and apply these learnings to help other species to survive and thrive. Anticipated outcomes include innovative approaches to aid conservation decision-making, automated analyses of genome data, and improved conservation training. The expected benefits include larger, healthier populations of four species, new ways of saving other species, and the provision of important resources for conservation managers.Read moreRead less
Genetic rescue of Australian wildlife. Genetic rescue of Australian wildlife. This project aims to test genetic rescue as an efficient recovery technique for threatened plants and animals. Genetic rescue is under-utilised, even though it is overwhelmingly beneficial. This project will convert management actions on five Endangered/Critically Endangered species into rigorous experiments that measure the fitness benefits of genetic rescue, and demonstrate genome-wide consequences. Anticipated outco ....Genetic rescue of Australian wildlife. Genetic rescue of Australian wildlife. This project aims to test genetic rescue as an efficient recovery technique for threatened plants and animals. Genetic rescue is under-utilised, even though it is overwhelmingly beneficial. This project will convert management actions on five Endangered/Critically Endangered species into rigorous experiments that measure the fitness benefits of genetic rescue, and demonstrate genome-wide consequences. Anticipated outcomes include innovative genetic rescue protocols, a framework for genetic rescue, and leading-edge conservation training. Expected benefits are increased persistence of species that are otherwise unresponsive to management, and a new path to saving endangered species.Read moreRead less
Flipping the mattress: infinite polyurethane recycling by synthetic biology. Australia is covered in billions of tonnes of plastic and yet <10% is recycled today. Polyurethane (PU) is ubiquitous in our everyday lives, from lacquer coatings to elastane clothing to durable foam padding in car seats, cushions and mattresses. Currently, there are few avenues for PU recycling and much ends up in landfill e.g., a single mattress produces 15-20kg of PU foam waste. Luckily, biodegradation of PU can occu ....Flipping the mattress: infinite polyurethane recycling by synthetic biology. Australia is covered in billions of tonnes of plastic and yet <10% is recycled today. Polyurethane (PU) is ubiquitous in our everyday lives, from lacquer coatings to elastane clothing to durable foam padding in car seats, cushions and mattresses. Currently, there are few avenues for PU recycling and much ends up in landfill e.g., a single mattress produces 15-20kg of PU foam waste. Luckily, biodegradation of PU can occur naturally via various microbial means and from insects, like Galleria mellonella larvae. The overall aim of this research project is to understand plastic biodegradation and translate nature’s solutions into flexible and efficient synthetic enzyme technologies that can sustainably recycle commonly used PU foams. Read moreRead less
A global standard for the status of Wetlands of International Importance. The project will develop and test a new global standard for the assessment and reporting on ecological condition of internationally important wetlands, listed under the Ramsar Convention. It has four aims: establishment of a strategic adaptive management and governance framework, a meta-analysis of the 2,303 internationally listed wetlands, development of a protocol for assessment and prediction and delivering a digital re ....A global standard for the status of Wetlands of International Importance. The project will develop and test a new global standard for the assessment and reporting on ecological condition of internationally important wetlands, listed under the Ramsar Convention. It has four aims: establishment of a strategic adaptive management and governance framework, a meta-analysis of the 2,303 internationally listed wetlands, development of a protocol for assessment and prediction and delivering a digital reporting platform for effective management. The project is significant because it tackles the decline of freshwater ecosystems, by targeting the most prominent wetlands. It also assists state and national governments to meet their obligations under the Ramsar Convention and most importantly guides more effective management.Read moreRead less
Assessing risk of oligomictic conditions in sub-tropical water supply lakes. Assessing risk of oligomictic conditions in sub-tropical water supply lakes. This project aims to assess the risk of low rates of mixing in sub-tropical drinking water supply reservoirs, using environmental monitoring and numerical modelling. Emerging evidence suggests sub-tropical drinking water supply reservoirs could transition to low mixing states with increasing age and projected changes in global climate. While th ....Assessing risk of oligomictic conditions in sub-tropical water supply lakes. Assessing risk of oligomictic conditions in sub-tropical water supply lakes. This project aims to assess the risk of low rates of mixing in sub-tropical drinking water supply reservoirs, using environmental monitoring and numerical modelling. Emerging evidence suggests sub-tropical drinking water supply reservoirs could transition to low mixing states with increasing age and projected changes in global climate. While this risk is poorly understood, it could significantly affect the long-term reliability of water supply and potable water treatment costs. Addressing this knowledge gap is expected to develop effective management responses to ensure the long term sustainable use of these water resources.Read moreRead less
Protein biosensors for detecting smoke exposure of grapes. Bush fires and controlled burns that take place in the vicinity of vineyards can lead to grape contamination with tasteless phenolic glucosides. Their hydrolysis during wine making leads to “smoke taint” – an unpleasant medicinal taste that can render wine undrinkable. We will apply a combination of organic synthesis, protein engineering and directed evolution to develop protein-based biosensors of phenolic glucosides. These biosensors w ....Protein biosensors for detecting smoke exposure of grapes. Bush fires and controlled burns that take place in the vicinity of vineyards can lead to grape contamination with tasteless phenolic glucosides. Their hydrolysis during wine making leads to “smoke taint” – an unpleasant medicinal taste that can render wine undrinkable. We will apply a combination of organic synthesis, protein engineering and directed evolution to develop protein-based biosensors of phenolic glucosides. These biosensors will be used to devise a simple portable colorimetric test that can be performed in the vineyard or the winery. The ability to rapidly determine the level of grape contamination with phenolic glucosides would give Australian wine growers and wine makers a powerful tool to mitigate the effects of bushfires.Read moreRead less
Digging deeper to improve yield stability. This project aims to provide innovative breeding solutions that harness the ‘hidden’ part of the plant, roots, to support the development of more productive crops in the face of climate variability. The project expects to generate new insights into the biology and genetics of root development in barley, a model cereal crop, by applying cutting-edge genome editing, phenotyping and genomics technologies. Anticipated outcomes include novel methodologies to ....Digging deeper to improve yield stability. This project aims to provide innovative breeding solutions that harness the ‘hidden’ part of the plant, roots, to support the development of more productive crops in the face of climate variability. The project expects to generate new insights into the biology and genetics of root development in barley, a model cereal crop, by applying cutting-edge genome editing, phenotyping and genomics technologies. Anticipated outcomes include novel methodologies to accelerate breeding for diverse production environments, with direct applications in barley, and other major cereals including wheat and oats. This should provide significant economic and social benefits to the Australian grains industry through yield stability amidst climate variability.Read moreRead less
Ancestral enzyme engineering for designer fat products. Consumers are increasingly turning to plant-based alternatives of meat and dairy products due to concerns about health, animal welfare and sustainability. Taste, nutritional profile, protein content and limited variety are barriers that continue to challenge food manufacturers. This project aims to develop a process for the fermentation of specialty food oils and fats from agriculture production waste, that can deliver the flavour and nutri ....Ancestral enzyme engineering for designer fat products. Consumers are increasingly turning to plant-based alternatives of meat and dairy products due to concerns about health, animal welfare and sustainability. Taste, nutritional profile, protein content and limited variety are barriers that continue to challenge food manufacturers. This project aims to develop a process for the fermentation of specialty food oils and fats from agriculture production waste, that can deliver the flavour and nutritional benefits of meat and dairy products when added to plant-based alternatives. The outcomes should valorise existing agriculture and food waste, converting waste materials into valuable food ingredients.Read moreRead less
Developing strong restorer-of-fertility genes for hybrid wheat breeding. Hybrid wheat varieties yield 10-15% more than conventional lines but a cost-effective system to produce hybrid seeds on a commercial scale is missing. This project aims to deliver such a system for use in hybrid wheat breeding programmes. The outcome will be ultimately higher wheat yield gains in Australia and worldwide. Higher and more stable yields will contribute to higher food security for the growing human population.