A Case-control Study Of Environment And Breast Cancer
Funder
National Health and Medical Research Council
Funding Amount
$808,948.00
Summary
Breast cancer is the most common cancer in Australian women and there have been a number of recent events which have raised public concern that occupational exposures are contributing to the increasing occurrence of this cancer. In this study, we will investigate occupational causes of breast cancer, particularly shift work, industrial solvent use and combustion products. We will compare occupations of 1000 women with breast cancer and 2000 women without cancer.
Markers Of Androgen Action, Genetic Variation And Prostate Cancer Risk
Funder
National Health and Medical Research Council
Funding Amount
$798,907.00
Summary
This proposal aim to follow up evidence from a number of studies that genetic and non-genetic markers of hormonal action in different periods of a man's life are associated with prostate cancer risk using a collection of three large, independent epidemiologic studies on prostate cancer named the Prostate Cancer Program. A principal objective is to collect exposure data on acne and digit ratio, and genotype cases and controls across the studies of the Prostate Cancer Program for common genetic va ....This proposal aim to follow up evidence from a number of studies that genetic and non-genetic markers of hormonal action in different periods of a man's life are associated with prostate cancer risk using a collection of three large, independent epidemiologic studies on prostate cancer named the Prostate Cancer Program. A principal objective is to collect exposure data on acne and digit ratio, and genotype cases and controls across the studies of the Prostate Cancer Program for common genetic variants in 4 candidate genes in the hormonal pathway. The established risk factors for prostate cancer are only age, race and family history. We anticipate that this project will cast light on the role of hormones in prostate cancer and that we will identify new markers of risk of prostate cancer and markers of disease aggressiveness. These outcomes will help us identifying men who are at risk for prostate cancer to target screening and surveillance, and plan prevention strategies. Furthermore, they will also form the basis for research on treatment targets.Read moreRead less
Performance evaluation and characterisation for filtering in multi-object system. The project falls within the National Research Priority of 'Safeguarding Australia' and associated research priority goal of 'Transforming Defence Technology'. The project outcomes will provide cutting edge technology in surveillance, and monitoring of potential threat in our air, sea, and land space. Fast, reliable information enable our personnel to make timely, intelligent judgements, and appropriate responses i ....Performance evaluation and characterisation for filtering in multi-object system. The project falls within the National Research Priority of 'Safeguarding Australia' and associated research priority goal of 'Transforming Defence Technology'. The project outcomes will provide cutting edge technology in surveillance, and monitoring of potential threat in our air, sea, and land space. Fast, reliable information enable our personnel to make timely, intelligent judgements, and appropriate responses in the event of a threat, thereby maintaining Australia's operational advantage. Other application areas that benefits from our research include radar, sonar, guidance, navigation, air traffic control, image processing, oceanography, autonomous vehicles and robotics, remote sensing, and biomedical research.
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Modelling patient flows through hospitals: optimizing effective use of resources. Hospitals are complex, dynamic systems confronted by increased demand in the face of shrinking real capacity. Managing such systems is currently undertaken with sub-optimal analytical support, particularly when demand and capacity are changing and resources must be manipulated to respond to such changes. In this project, the investigators will apply a mathematical modelling approach to the analysis of hospital pati ....Modelling patient flows through hospitals: optimizing effective use of resources. Hospitals are complex, dynamic systems confronted by increased demand in the face of shrinking real capacity. Managing such systems is currently undertaken with sub-optimal analytical support, particularly when demand and capacity are changing and resources must be manipulated to respond to such changes. In this project, the investigators will apply a mathematical modelling approach to the analysis of hospital patient flows. Furthermore, they will employ statistical process control methodologies to the problem of recognising and responding to changes in the flows, so that performance objectives are met. In doing this, they will give health service managers and clinicians a significant advantage in deciding how best to manage a constrained resource to maximize access, throughput and patient outcomes.Read moreRead less
Optimal Control of Multi-Object System. Better understanding of multi-object systems developed from this research, in particular, optimal control algorithms for multi-object systems have several significant socio-economic benefits. Application areas that benefits from our research include aerospace applications such as radar, sonar, guidance, navigation, and air traffic control and non-aerospace areas such as image processing, oceanography autonomous vehicles and robotics, remote sensing, and bi ....Optimal Control of Multi-Object System. Better understanding of multi-object systems developed from this research, in particular, optimal control algorithms for multi-object systems have several significant socio-economic benefits. Application areas that benefits from our research include aerospace applications such as radar, sonar, guidance, navigation, and air traffic control and non-aerospace areas such as image processing, oceanography autonomous vehicles and robotics, remote sensing, and biomedical research. The sensor network discipline also stand to benefit from the understanding of multi-object system and control framework. Read moreRead less
Queueing systems and their application to telecommunication systems and dams. The aim of this project is to investigate the behaviour of large queueing systems under critical load conditions and solve problems related to large telecommunication systems, information technologies and dams. The project will have significant economic and social benefits. It will lead to the solution of high priority problems of optimal control of water resources, as well as problems in design technology of high spee ....Queueing systems and their application to telecommunication systems and dams. The aim of this project is to investigate the behaviour of large queueing systems under critical load conditions and solve problems related to large telecommunication systems, information technologies and dams. The project will have significant economic and social benefits. It will lead to the solution of high priority problems of optimal control of water resources, as well as problems in design technology of high speed telecommunication networks. It will suggest new more profitable approaches to known problems such as effective bandwidth problem, analysis and design of computer networks, optimal control of dams, and anticipate not ordinary results and solutions. It will contribute to the mathematical culture in Australia and worldwide. Read moreRead less
The Australian naturalistic driving study: innovation in road safety research and policy. A revolutionary new approach, the naturalistic driving study, will investigate what people actually do when they drive, in normal and safety-critical situations. It will provide Australia with answers to some intractable, high priority, road safety problems that cannot be answered using current methods, thereby saving hundreds of lives.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE130100050
Funder
Australian Research Council
Funding Amount
$570,000.00
Summary
Integrated facility for recording driver and road user behaviour. The integrated facility will be used to record and analyse data on driver and road user behaviour, in normal and safety-critical situations, for thousands of Australian drivers. The data yielded will be used to develop new and improved countermeasures for reducing road deaths and serious injuries on Australian roads.
Robust Optimal Asset Liability Management via Stochastic Control Theory. The Australian federal and state governments are strongly exposed to the Australian and international investment markets, either directly or through entities such as the Future Fund, state-owned insurers and superannuation schemes. Additionally, the investment pool represented by individual Australian's superannuation savings managed by non-government organisations is significant. Robust and effective management of these ....Robust Optimal Asset Liability Management via Stochastic Control Theory. The Australian federal and state governments are strongly exposed to the Australian and international investment markets, either directly or through entities such as the Future Fund, state-owned insurers and superannuation schemes. Additionally, the investment pool represented by individual Australian's superannuation savings managed by non-government organisations is significant. Robust and effective management of these assets in order to meet future liabilities of these funds are essential to a stable Australian economy. This research has the potential to be a key component of reliable investment management, helping make Australia an important investment hub.Read moreRead less
The Centre for Research Excellence in Nursing Interventions for Hospitalised Patients will provide evidence to improve the nursing care of a broad range of hospitalised patients who are at risk of complications related to compromised skin integrity and poor pain/anxiety management. Systematic reviews and clinical trials will provide the basis for developing clinical practice guidelines to assist nurses in providing high quality care to the 3.5 million Australians admitted to hospital each year.