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Guaranteeing Survival Into Adulthood, Physical Health And Psychological Well-being To Children Born With Single Ventricles.
Funder
National Health and Medical Research Council
Funding Amount
$342,773.00
Summary
Being born with a single pumping heart chamber is the most severe heart condition but thanks to several operations we can see them survive. A growing population of young functional adults now face an uncertain future and we have no options for them. A/Pr Y d’Udekem is a leading paediatric cardiac surgeon. His research aims to provide the medications, reinterventions and artificial hearts that are necessary to give them a longer and fulfilling life.
Atrial fibrillation (AF) is the most common cause for an irregular heart beat. Catheter ablation is the only potential cure and involves passing wires via veins in the leg into the heart to deliver discrete small burns(ablation) around the pulmonary veins (PV), the major source for AF. Unfortunately 30-50% of patients have recurrent arrhythmia due to reestablishment of electrical connections. This multicentre internation trial examines whether more (maximal) ablation will improve the outcomes of ....Atrial fibrillation (AF) is the most common cause for an irregular heart beat. Catheter ablation is the only potential cure and involves passing wires via veins in the leg into the heart to deliver discrete small burns(ablation) around the pulmonary veins (PV), the major source for AF. Unfortunately 30-50% of patients have recurrent arrhythmia due to reestablishment of electrical connections. This multicentre internation trial examines whether more (maximal) ablation will improve the outcomes of the procedure.Read moreRead less
Improving The Impact Of Perioperative Clinical Trials
Funder
National Health and Medical Research Council
Funding Amount
$494,733.00
Summary
This research focuses on (i) Designing and conducting large multicentre trials in anaesthesia and surgery, (ii) Confirming new patient-centred outcome measures in surgery, such as patient-rated quality of recovery, returning home after surgery, and disability-free survival; and (iii) Innovative trial designs to improve the efficiency (less burden, lower costs) of trials.
Advances in anaesthesia and perioperative medicine have resulted in safer care and better quality outcomes for patients having major surgery. Such advances need to be based on good quality evidence, coming from large randomised clinical trials. This research program will study, publish and disseminate information from studies of new drugs and techniques that improve the care of patients undergoing surgery.
I am an orthopaedic surgeon and clinician-scientist based at Sydney’s largest children’s hospital. My goal is to improve treatments for children with traumatic injuries and bone deformity. I have worked in bone research for over 20 years. My current research interests are finding new treatments for drug-resistant bacterial infections, treating genetic bone disease, and developing new medical devices to help children’s bones grow straight.
Improving The Outcome Of Critically Ill Patients Through The Generation Of Evidence And Its Translation Into Practice
Funder
National Health and Medical Research Council
Funding Amount
$329,822.00
Summary
This research program will test new approaches to sepsis, traumatic brain injury, kidney protection, nutrition, post-operative care, sedation, cardiac arrest, and mobilisation of acutely ill patients to deliver better outcomes. Experimental research will help understand kidney injury during severe infection and develop new ways of protecting the brain during cardiac arrest. Database investigations will identify successful patterns of treatment and potential new fields of investigations.
Developing Improved Management For Peripheral Artery Diseases
Funder
National Health and Medical Research Council
Funding Amount
$569,219.00
Summary
~1 million Australians have peripheral artery disease. The current application is for a Practitioner Fellowship to support my research aimed at improving care of artery disease. The aim of the work is to develop improved management approaches for patients with blocked and weakened arteries. This work is particularly important given the recognised management deficiencies for patients with artery disease and the relative little research being undertaken in this area.
Atrial fibrillation (AF) has reached epidemic proportions. It results in significant burden to the individual and community with palpitations, falls, strokes, and heart failure which have contributed to an exponential rise in health care usage and hospitalisation. This application will focus on the optimal management of AF with a focus not only on therapeutics but importantly on the prevention of the arrhythmia and minimising hospitalisation.
Structural And Functional Networks In The Human Brain: Disturbance In Disease And Influence Of Genes.
Funder
National Health and Medical Research Council
Funding Amount
$568,892.00
Summary
Professor Graeme Jackson is a Neurologist at the Austin Hospital whose research is dedicated to the problem of understanding how epilepsy occurs and devising strategies for successful treatment. He is Deputy Director and head of the epilepsy division of the Florey Neuroscience Institutes which has research dedicated advanced MR imaging systems and physics support largely dedicated to solving these problems in epilepsy. He has 170 plus papers, 10 cited over 200 times. Career citations exceed 6000 ....Professor Graeme Jackson is a Neurologist at the Austin Hospital whose research is dedicated to the problem of understanding how epilepsy occurs and devising strategies for successful treatment. He is Deputy Director and head of the epilepsy division of the Florey Neuroscience Institutes which has research dedicated advanced MR imaging systems and physics support largely dedicated to solving these problems in epilepsy. He has 170 plus papers, 10 cited over 200 times. Career citations exceed 6000.Read moreRead less
Better Care Of Heart And Lung Disease For Aboriginal And Torres Strait Islander People In Rural And Remote Australia
Funder
National Health and Medical Research Council
Funding Amount
$380,583.00
Summary
Lung and heart disease are major contributors to the Aboriginal Australian and Torres Strait Islander health gap. This is even more so in remote and regional Australia. This Fellowship will generate new knowledge regarding how best to prevent, diagnose and treat heart and lung disease in this setting. Based in Alice Springs, it will bring together researchers and health care providers across northern and Central Australia and link them with our leading national research institutes.