Transcriptome Landscape Of Brown/beige Adipogenesis In Humans
Funder
National Health and Medical Research Council
Funding Amount
$393,369.00
Summary
There are three kinds of fat in the body: white, brown and beige. While excess white fat results in obesity, brown fat is associated with leanness and lowers blood glucose levels. Recent animal experiments show that under certain conditions, white fat can be transformed into beige fat, leading to benefits such as weight loss. The current project grant involves examination of human fat cells grown in the laboratory and investigation on the genetics of brown and beige fat.
Swirling turbulent pipe flow technology for drying brown coal. This project aims to understand the complex fluid mechanicalprocesses in a brown coal drying machine. Brown coal from the Latrobe Valley contains about 70 percent moisture, which must be reduced for it to be used efficiently in power stations. Utilising cutting-edge techniques in laboratory and field measurements together with advanced computational methods in fluid mechanics, the project intends to further knowledge in swirling turb ....Swirling turbulent pipe flow technology for drying brown coal. This project aims to understand the complex fluid mechanicalprocesses in a brown coal drying machine. Brown coal from the Latrobe Valley contains about 70 percent moisture, which must be reduced for it to be used efficiently in power stations. Utilising cutting-edge techniques in laboratory and field measurements together with advanced computational methods in fluid mechanics, the project intends to further knowledge in swirling turbulent flows, particle transport and vortex breakdown. The result of this research is expected to produce a drier brown coal, leading to a cleaner environment and an increase in Australian coal value. Read moreRead less
Transgenerational Effects Of Male Obesity - Mechanisms And Interventions
Funder
National Health and Medical Research Council
Funding Amount
$829,143.00
Summary
Childhood obesity is associated with obesity in either parent, and obese children tend to become obese adults, forming an intergenerational cycle that promotes obesity. We have identified paternal obesity as an important novel target for intervention to stop the progression of the obesity epidemic. This project investigates supplementation of obese fathers with folate to prevent the adverse impact of paternal obesity on subsequent generations.
Chemerin, A Novel Therapeutic Target For Modulation Of Adipose Tissue Mass
Funder
National Health and Medical Research Council
Funding Amount
$535,621.00
Summary
Obesity is a significant public health issue due to its increasing prevalence and association with other diseases including cardiovascular disease. Efforts to pharmacologically prevent and treat obesity are impaired by an incomplete understanding of the genes and metabolic processes involved. This project will use cell and animal models to examine the processes that occur during the expansion of fat tissue which will broaden our understanding of obesity and assist in identifying new therapies.