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In-vivo detection of airway injury and disease using phase contrast X-ray velocimetry. Currently diagnosis of lung disease, a major cause of death in humans, is based on clinical symptoms that do not usually manifest until the disease is well advanced. This project will develop a novel imaging technique, X-ray velocimetry, to detect changes in tissue before symptoms arise, potentially leading to strategies for managing lung diseases.
Low dose methods for detecting early lung disease using x-ray phase contrast imaging. This project will develop a highly sensitive, low-dose x-ray imaging technique for the early detection of diseases of the respiratory system. This technology will have the potential to be used as a diagnostic screening tool to reduce the incidence of respiratory related deaths from diseases such as lung cancer and emphysema.
Advanced imaging technology for measuring pulmonary form and function. Studies of the lung are often limited by difficulties associated with imaging the complex network of airways with conventional techniques. This project will develop novel phase contrast image x-ray imaging technologies to enable quantitative measurements of lung structure and function for studying lung development and assessing lung health.
Discovery Early Career Researcher Award - Grant ID: DE120102571
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Visualising living airways: a new x-ray technique to assess Cystic Fibrosis treatments. The ability to non-invasively observe the body's inner functions at high magnification is critical in developing new medical treatments. This project will establish an x-ray technique capable of imaging subtle biological function at high magnification and apply this technique to assessing new treatments for airways affected by Cystic Fibrosis.