The Australian Research Data Commons (ARDC) invites you to participate in a short survey about your
interaction with the ARDC and use of our national research infrastructure and services. The survey will take
approximately 5 minutes and is anonymous. It’s open to anyone who uses our digital research infrastructure
services including Reasearch Link Australia.
We will use the information you provide to improve the national research infrastructure and services we
deliver and to report on user satisfaction to the Australian Government’s National Collaborative Research
Infrastructure Strategy (NCRIS) program.
Please take a few minutes to provide your input. The survey closes COB Friday 29 May 2026.
Complete the 5 min survey now by clicking on the link below.
The Haemodynamic Effects Of Cardiac Compression By Large Hiatal Hernia And The Relationship To Exercise Impairment.
Funder
National Health and Medical Research Council
Funding Amount
$117,270.00
Summary
Large hiatal herniae (HH) often cause debilitating exercise intolerance - the mechanism of which is unknown. This project will define the functional and haemodynamic significance of cardiac compression in patients with large HH, providing new insights into the mechanism of exercise impairment in these patients as well as clinical tools for pre-operative selection of patients likely to benefit most from surgical repair.
Telehealth And Advanced CT Imaging Combined Study (TACTICS)
Funder
National Health and Medical Research Council
Funding Amount
$979,270.00
Summary
This project aims to converge several acute stroke therapy systems of care to provide the best possible health outcomes for patients living in regional areas. We will implement a proven telehealth program with the aim of providing increased access to thrombolysis through screening with multimodal CT. During this project we will also undertake a nested randomised trial of advanced imaging to identify which is the most efficient imaging protocol to ensure the best possible patient outcomes
Examining Genome Wide Gene Expression Changes During Cardiac Injury And Regeneration
Funder
National Health and Medical Research Council
Funding Amount
$351,852.00
Summary
Heart attacks are the leading cause of death in Australia. Following a heart attack, the loss of beating heart cells is replaced with a permanent scar and this limits the heart from functioning properly. The zebrafish can uniquely recover from a heart attack. New heart cells are generated rather than scar formation. This project will use the zebrafish to identify new signals that promote heart regeneration and can potentially be applied in human hearts to reverse the damage following injury.
This proposal aims to examine central mechanisms important in stress related hypertension. My team will focus on the role of tissue plasminogen activator in mediating inhibitory effects of chronic stress on neural plasticity and examine inhibitory dysfunction in GABAergic and nitric oxide pathways that lead to increased sympathetic activity and elevated blood pressure. Importantly, we will investigate the potential of three interventions directed at each as therapies for hypertension.
The Effect Of Moderate And High Intensity Exercise On Cardiovascular Health And Cardiac Remodelling
Funder
National Health and Medical Research Council
Funding Amount
$110,615.00
Summary
The interface between exercise, risk markers, atherosclerosis and cardiac function remains an understudied area of great public health importance. Our project will assess the effect of moderate and high intensity exercise on markers of cardiovascular disease (CVD) and cardiac remodelling.
Defining Targets And Establishing Methods For Prevention, Diagnosis And Therapy Of Inflammation, Atherosclerosis And Thrombosis
Funder
National Health and Medical Research Council
Funding Amount
$847,490.00
Summary
My research focuses on preventing and treating atherosclerotic disease and its complications such as heart attack and stroke. This will be achieved by developing new imaging technologies, with the aim to detect unstable atherosclerotic plaques, as well as innovative new drugs preventing inflammation and thrombosis as the major contributors of heart attack and stroke.
The Unstable, Rupture-prone Atherosclerotic Plaque: Innovative Methods For Its Detection And Stabilisation
Funder
National Health and Medical Research Council
Funding Amount
$748,447.00
Summary
Heart attacks and strokes are most often caused by rupture of unstable atherosclerotic plaques resulting in clotting and vessel occlusion and ultimately irreversible damage of the heart or brain. We have generated a mouse model that reproduces these plaques as seen in humans. Based on this model and human unstable plaques 1) we have discovered/developed imaging technologies that can identify these dangerous plaques and 2) we will develop drugs that prevent plaque rupture.
Ventricular Remodelling In Cardiomyopathy _ Impact On Ventricular Physiology And Cardiovascular Outcome.
Funder
National Health and Medical Research Council
Funding Amount
$123,337.00
Summary
Diffuse myocardial fibrosis is the widespread deposition of scar tissue in heart muscle and is a common final pathway of cardiac disease. A new technique (contrast-enhanced T1 mapping) using cardiac magnetic resonance imaging can non-invasively detect this scarring. The proposed research intends to further determine the significance of diffuse myocardial fibrosis in cardiac disease, evaluate its link with diastolic heart failure and examine the potential therapeutic role of anti-fibrotic agents.