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Time-domain Analysis Of Right Ventricular-pulmonary Arterial Coupling As A Windkessel And Wave System.
Funder
National Health and Medical Research Council
Funding Amount
$64,631.00
Summary
We seek to determine the number of people affected by pulmonary arterial hypertension (high blood pressure in the lungs) in Tasmania by collecting information from echocardiograms (heart ultrasounds). This is important because the incidence and prevalence is unknown but suspected to be unusually high in Tasmania. Also simultaneous pulmonary arterial pressure and velocity waves will be studied in humans to model pulmonary flow in an attempt to recognise pulmonary arterial hypertension earlier.
Coronary Atherosclerosis And Its Relationship With Platelet Activation
Funder
National Health and Medical Research Council
Funding Amount
$101,039.00
Summary
Blood clots are critical to the development of heart attacks, which kill many thousands of Australians annually. Platelets are cells in the blood that play an essential role in formation of blood clots, and coronary disease is associated with platelet activation. This research study will investigate the nature of platelet activation in the arteries of the human heart, its relationship to activation of inflammatory cells, and to the severity of narrowings in the arteries of the human heart.
Blood And Blood Product Transfusion In Trauma Resuscitation
Funder
National Health and Medical Research Council
Funding Amount
$98,431.00
Summary
Blood is an exceedingly scarce and expensive resource. Massive transfusions place enormous strains on blood banks. There is little consensus and a paucity of evidence on transfusion practice in major trauma. Trauma patients account for a significant proportion of all patients who receive transfusions. This project will assist with the development of more uniform guidelines for transfusion of blood products in major trauma patients based on the best evidence available and current practice.
Retinal Vascular Structure And Function As Markers Of Endothelial Dysfunction.
Funder
National Health and Medical Research Council
Funding Amount
$104,664.00
Summary
Coronary heart disease (CHD) due to atherosclerosis (thickening of blood vessels) remains the leading cause of death in Australia, but visualisation of heart arteries usually requires invasive testing. Blood vessels in the eye (retina), can be viewed easily and may be indicative of blood vessel function in the heart and rest of the body. This study aims to explore the relationship between eye and heart blood vessels. Retinal imaging may thus enable earlier detection of patients at risk of CHD.