Blood And Blood Product Transfusion In Trauma Resuscitation
Funder
National Health and Medical Research Council
Funding Amount
$98,431.00
Summary
Blood is an exceedingly scarce and expensive resource. Massive transfusions place enormous strains on blood banks. There is little consensus and a paucity of evidence on transfusion practice in major trauma. Trauma patients account for a significant proportion of all patients who receive transfusions. This project will assist with the development of more uniform guidelines for transfusion of blood products in major trauma patients based on the best evidence available and current practice.
Improving Patient Outcomes Through Understanding And Changing Transfusion Practice
Funder
National Health and Medical Research Council
Funding Amount
$75,347.00
Summary
Blood transfusion has a central role in many areas of clinical medicine. Despite its widespread use, there are large areas where evidence to inform clinical practice is limited. The aim of this proposed research is to investigate the current use of blood products in clinical medicine. Data on blood transfusion will be linked with existing clinical registries to examine how transfusion practice influences patient outcomes in a range of clinical areas including trauma, surgery and critical care.
Design And Use Of Conductive Biopolymers In Neural Stem Cell Network Formation
Funder
National Health and Medical Research Council
Funding Amount
$74,055.00
Summary
Growing neural tissue from stem cells on an electrically conductive surface can improve cell growth over the short term, yet the functionality of the cells has never been fully established. We will investigate the use of polymers for facilitation of neural tissue growth from stem cells, test the functionality of the tissue produced, and investigate the effectiveness of implantation of the developed tissue into primates to supplement or replace damaged tissue.
Time-domain Analysis Of Right Ventricular-pulmonary Arterial Coupling As A Windkessel And Wave System.
Funder
National Health and Medical Research Council
Funding Amount
$64,631.00
Summary
We seek to determine the number of people affected by pulmonary arterial hypertension (high blood pressure in the lungs) in Tasmania by collecting information from echocardiograms (heart ultrasounds). This is important because the incidence and prevalence is unknown but suspected to be unusually high in Tasmania. Also simultaneous pulmonary arterial pressure and velocity waves will be studied in humans to model pulmonary flow in an attempt to recognise pulmonary arterial hypertension earlier.
Coronary Atherosclerosis And Its Relationship With Platelet Activation
Funder
National Health and Medical Research Council
Funding Amount
$101,039.00
Summary
Blood clots are critical to the development of heart attacks, which kill many thousands of Australians annually. Platelets are cells in the blood that play an essential role in formation of blood clots, and coronary disease is associated with platelet activation. This research study will investigate the nature of platelet activation in the arteries of the human heart, its relationship to activation of inflammatory cells, and to the severity of narrowings in the arteries of the human heart.