Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0989125
Funder
Australian Research Council
Funding Amount
$150,000.00
Summary
Enhanced Capacity in Ultra-Trace Level Detection and Speciation of Compounds of Environmental, Biological and Materials Science Interest. The proposed integrated facility will strongly support collaborative research in areas of high national priority. These are environmental sustainability, development of new materials and designing molecules of therapeutic value on the basis of better understanding the relevant biological processes. This support will lead to maximizing the outcomes of numerous ....Enhanced Capacity in Ultra-Trace Level Detection and Speciation of Compounds of Environmental, Biological and Materials Science Interest. The proposed integrated facility will strongly support collaborative research in areas of high national priority. These are environmental sustainability, development of new materials and designing molecules of therapeutic value on the basis of better understanding the relevant biological processes. This support will lead to maximizing the outcomes of numerous projects already funded by the Australian Research Council which require accurate and highly sensitive analysis. This will improve the cost effectiveness of research funding and will further strengthen the outstanding reputation of Australia science worldwide.Read moreRead less
Characterisation of the oxygen-sensing asparaginyl hydroxylase, FIH-1, and hydroxylase-specific antagonists. This research will provide fundamental information on how cells and whole organisms can sense and respond accordingly to oxygen deficiency. This information is fundamental for our understanding of embryo development and adult life in different environments, and central to the diagnosis and treatment of diseases such as stroke, cardiovascular disease, and cancer. This research will contrib ....Characterisation of the oxygen-sensing asparaginyl hydroxylase, FIH-1, and hydroxylase-specific antagonists. This research will provide fundamental information on how cells and whole organisms can sense and respond accordingly to oxygen deficiency. This information is fundamental for our understanding of embryo development and adult life in different environments, and central to the diagnosis and treatment of diseases such as stroke, cardiovascular disease, and cancer. This research will contribute to our basic knowledge of these processes, provide invaluable information about the specific genes and proteins involved, and provide direct information about the therapeutic potential of specific drugs or inhibitors designed to target this oxygen response in human disease.Read moreRead less