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This research investigates the factors regulating the transition of the lung from the fluid filled organ in fetal life to the air filled organ required at birth. Many preterm babies fail this transition and in order to survive, their lungs often require mechanical ventilation, which has been suggested to cause lung injury. Using synchrotron generated X-rays, we can determine how particular resuscitation techniques are able to reduce this injury and promote aeration at birth.
An Examination Of The Quality And Acceptability Of Maternal Health Services For Remote Dwelling Aboriginal Women And Infants From The Top End Of Australia
Funder
National Health and Medical Research Council
Funding Amount
$56,838.00
Summary
Aboriginal women have long demanded changes in maternity healthcare services. It was anticipated that the implementation of a Midwifery Group Practice (MGP) would decrease fragmentation of care and improve maternal infant health outcomes. The research aims to determine if a changed model of care for remote dwelling Aboriginal women who transfer to Darwin for birth has increased the acceptability of services to women and improved outcomes for mothers and infants.
Signalling And Transcriptional Activity For Craniofacial Morphogenesis In An Experimental Genetic Mouse Model
Funder
National Health and Medical Research Council
Funding Amount
$74,755.00
Summary
Abnormalities in craniofacial development affect 2-1000 births in Australia. The aim of this project is to identify genes crucial for the development of the head and face. In particular the project focuses on the Twist1 gene. TWIST1 plays a key role in craniofacial development and individuals lacking functional Twist1display facial anomalies such as craniosynostosis and cleft palate. Dissecting the function of Twist1 is essential to identifying new avenues for the prevention of these defects.