Development of dense gas technology platforms for the formulation of oral vaccines. This project will aim to develop a technology platform that enables the formulation of vaccines that can be delivered orally and this research has the potential to radically change existing vaccination regimens. The availability of needle-free vaccination also has potential for considerable societal and economic impact in developing countries.
Development of a light detection system for enhanced scanning electron microscopy imaging of fully hydrated biological specimens at room temperature. This project aims to develop instrumentation and techniques to image fully hydrated cellS for prolonged periods at room temperature in an environmental scanning electron microscope. Multiple fluorescent nano-particle labels will be used to image complex cellular structure and dynamics at ultra high spatial resolution. This innovative bio-imaging te ....Development of a light detection system for enhanced scanning electron microscopy imaging of fully hydrated biological specimens at room temperature. This project aims to develop instrumentation and techniques to image fully hydrated cellS for prolonged periods at room temperature in an environmental scanning electron microscope. Multiple fluorescent nano-particle labels will be used to image complex cellular structure and dynamics at ultra high spatial resolution. This innovative bio-imaging technique will be facilitated by the construction of a high speed light collection system that can efficiently operate at the pressures required to stablise water within the cell. Applications for this new bio-imaging technique will also be explored.Read moreRead less
Rapid Pathogen Detection using Super-Sensitive Multiplexing Nanophotonic Probes. Responding to an urgent need to advance rapid molecular diagnostics, this project aims to explore new photonics and biochemistry approaches to DNA recognition. It is anchored on proprietary light-emitting nanodots which have single-molecule sensitivity in conjunction with tunable optical identities. The project aims to develop a multiplexing reagent library of DNA probes to sense trace DNA molecules and to recognise ....Rapid Pathogen Detection using Super-Sensitive Multiplexing Nanophotonic Probes. Responding to an urgent need to advance rapid molecular diagnostics, this project aims to explore new photonics and biochemistry approaches to DNA recognition. It is anchored on proprietary light-emitting nanodots which have single-molecule sensitivity in conjunction with tunable optical identities. The project aims to develop a multiplexing reagent library of DNA probes to sense trace DNA molecules and to recognise multiple pathogens in a single assay. This innovation aims to create a hybrid-Polymerase Chain Reaction (PCR) technology platform for current industry-standard pathogen detection tests. The outcomes of the project aim to enable DNA based pathogen diagnostics within 90 minutes, four times faster than the current tests.Read moreRead less
Electronic skin nanopatches for continuous blood pressure monitoring. Electronic skin nanopatches for continuous blood pressure monitoring. This project aims to develop soft, thin, wearable and non-invasive heart health monitors that continuously monitor blood pressures anytime anywhere, using an electronic skin technology platform with the world’s thinnest gold nanowires. Nanotechnologists, electrical engineers, clinicians, information technologists and industrial designers will collaborate to ....Electronic skin nanopatches for continuous blood pressure monitoring. Electronic skin nanopatches for continuous blood pressure monitoring. This project aims to develop soft, thin, wearable and non-invasive heart health monitors that continuously monitor blood pressures anytime anywhere, using an electronic skin technology platform with the world’s thinnest gold nanowires. Nanotechnologists, electrical engineers, clinicians, information technologists and industrial designers will collaborate to develop blood pressure correlation algorithms and evaluate sensing performances. New knowledge and commercial technologies will make Australian medical technology industries competitive global leaders in wearable technology industries.Read moreRead less
A Nano-platform for affordable and ultra-sensitive bio-marker detection. This project aims to develop a next-generation nano-platform and lateral flow assays (LFA) device for ultra-sensitive detection of biomarkers. LFA’s are used for the rapid detection of biomarkers; however, their sensitivity is relatively low. The preparation of innovative porous silica nanoparticles with uniform particle size and controllable structures (pore size, pore structure, internal surface functionality and density ....A Nano-platform for affordable and ultra-sensitive bio-marker detection. This project aims to develop a next-generation nano-platform and lateral flow assays (LFA) device for ultra-sensitive detection of biomarkers. LFA’s are used for the rapid detection of biomarkers; however, their sensitivity is relatively low. The preparation of innovative porous silica nanoparticles with uniform particle size and controllable structures (pore size, pore structure, internal surface functionality and density) will enable higher loading of quantum dots and enhanced detection sensitivity. Improving the detection sensitivity of the inexpensive and disposable LFA diagnostic technology will open up new applications for rapid and accurate biomarker detection. The resulting technology will advance Australian industrial capability and competiveness in the global lateral flow assays market, which is estimated to be valued at US$ 6.78 billion by 2020.Read moreRead less