Industrial Transformation Research Hubs - Grant ID: IH150100028
Funder
Australian Research Council
Funding Amount
$3,708,510.00
Summary
ARC Research Hub for Integrated Device for End-user Analysis at Low-levels. ARC Research Hub for Integrated Device for End-user Analysis at Low-levels. This hub aims to improve detection of biological materials by building a portable device for rapid, time-critical detection of low-abundance molecular and cellular analytes. It is expected that the resulting technologies would be used at medical points of care, ordinary workplaces and centres of activity to test for tiny levels of targeted molecu ....ARC Research Hub for Integrated Device for End-user Analysis at Low-levels. ARC Research Hub for Integrated Device for End-user Analysis at Low-levels. This hub aims to improve detection of biological materials by building a portable device for rapid, time-critical detection of low-abundance molecular and cellular analytes. It is expected that the resulting technologies would be used at medical points of care, ordinary workplaces and centres of activity to test for tiny levels of targeted molecules. The initial focus would be early diagnosis of disease and point-of-care drug testing for humans and animals, but the technology platform could be used to sample food and environmental toxins. The hub expects these disruptive technologies will make Australian biotechnology, diagnostics, veterinary, agribusiness and manufacturing firms globally competitive.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0453935
Funder
Australian Research Council
Funding Amount
$220,106.00
Summary
Multi-Scale Fermentation Facility for Beverage Research. Australia's largest concentration of beverage fermentation research effort and infrastructure is arguably represented by the University of Adelaide and partners at the Waite Campus, particularly The Australian Wine Research Institute and Provisor Pty Ltd. This cluster seeks to establish an integrated, jointly managed, Multi-Scale Fermentation Facility for Beverage Research. This Facility will address critical shortages in fermentation capa ....Multi-Scale Fermentation Facility for Beverage Research. Australia's largest concentration of beverage fermentation research effort and infrastructure is arguably represented by the University of Adelaide and partners at the Waite Campus, particularly The Australian Wine Research Institute and Provisor Pty Ltd. This cluster seeks to establish an integrated, jointly managed, Multi-Scale Fermentation Facility for Beverage Research. This Facility will address critical shortages in fermentation capacity for research (volumes between 1 ml and 1000 L), offer a vertically integrated system to facilitate step-wise scale-up, allow more accurate modelling of industrial fermentations, enable greater adoption of high-throughput formats and technologies, and achieve enhanced productivity through increased system automation.Read moreRead less
Heterotrophically grown microalgae as a feed source for the Australian aquaculture industry. The Australian aquaculture industry has rapidly grown in the past decade producing premium quality, high value species, e.g. tuna and oyster. In the new millennia it is predicted that the Australia aquaculture industry will be the most profitable area within the Australian seafood industry. An integral component for the long-term sustainability of the Australian aquaculture industry is the availability o ....Heterotrophically grown microalgae as a feed source for the Australian aquaculture industry. The Australian aquaculture industry has rapidly grown in the past decade producing premium quality, high value species, e.g. tuna and oyster. In the new millennia it is predicted that the Australia aquaculture industry will be the most profitable area within the Australian seafood industry. An integral component for the long-term sustainability of the Australian aquaculture industry is the availability of top-quality microalgal concentrates, shelf-stable pastes or live feeds, which provide the nutritional requirements of aquatic species in the hatcheries. This project will develop novel microalgal production strategies that would add value to the Australian aquaculture industry.Read moreRead less
An Integrated Biotechnological Process for Production of Lactic Acid from Carbohydrate-Waste Streams by Rhizopus sp. Lactic acid is the most widely occurring multifunctional organic acid. It has enormous applications in food and food-related industries, and great potential use for production of biodegradable and biocompatible polylactate polymers. The aim of this research is to develop an innovative biotechnological process, incorporating simultaneous saccharification and fermentation, which int ....An Integrated Biotechnological Process for Production of Lactic Acid from Carbohydrate-Waste Streams by Rhizopus sp. Lactic acid is the most widely occurring multifunctional organic acid. It has enormous applications in food and food-related industries, and great potential use for production of biodegradable and biocompatible polylactate polymers. The aim of this research is to develop an innovative biotechnological process, incorporating simultaneous saccharification and fermentation, which integrates the production of lactic acid with the treatment of high strength food industry ?effluent? streams - carbohydrate waste streams. The proposed SSF process will cultivate an identified fungal Rhizopus sp strain on the waste streams, as production substrates, leading to an environmentally friendly and economically sustainable new technology for the food industry.Read moreRead less
Exploiting novel yeast attributes to produce industrial strains with better fermentative and processing qualities. Food and beverage fermentations are problematic processes, largely due to limitations of the yeast being used. This laboratory has indentified in individual yeast strains highly desirable fermentative characteristics or else the ability to over-produce compounds that benefit product processing. Pursuing the commercial potential of these findings is the specific objective of this pro ....Exploiting novel yeast attributes to produce industrial strains with better fermentative and processing qualities. Food and beverage fermentations are problematic processes, largely due to limitations of the yeast being used. This laboratory has indentified in individual yeast strains highly desirable fermentative characteristics or else the ability to over-produce compounds that benefit product processing. Pursuing the commercial potential of these findings is the specific objective of this proposal. Thus we will extend our collaboration with Coopers Brewery through this new project area with the aims of a) producing optimised, hybrid (non-GMO) strains with combinations of desirable fermentation properties, b) develop novel processing or quality-enhancing treatments while c) generating a high caliber PhD graduate with extensive industry experience.Read moreRead less
Application of Vortex Fluidics in Macroalgal Biorefinery. This project aims to improve seaweed processing to deliver multiple high-value products including alginate, fucoidan and laminarin, which have food, cosmetic and pharmaceutical uses. The project integrates an advanced biorefinery process with a vortex fluidic device to accelerate chemical reactions, reduce the catalysts and chemicals used, and improve product yield and productivity. Application of the device in the critical steps of enzym ....Application of Vortex Fluidics in Macroalgal Biorefinery. This project aims to improve seaweed processing to deliver multiple high-value products including alginate, fucoidan and laminarin, which have food, cosmetic and pharmaceutical uses. The project integrates an advanced biorefinery process with a vortex fluidic device to accelerate chemical reactions, reduce the catalysts and chemicals used, and improve product yield and productivity. Application of the device in the critical steps of enzymatic digestion, acid and alkaline extraction, and precipitation is intended to deliver significant water, energy, chemical and cost saving. It is anticipated that the innovation will lead to the establishment of a new sustainable seaweed processing industry in Australia.Read moreRead less
Drug Targeting to Immune Cells Using Modified Inulin Particles. Vaxine Pty Ltd is an Australian biotechnology company that has discovered specific particulate forms of inulin that are efficiently internalised by human immune cells. This project aims to exploit cell migration to injury and infection sites by attaching drugs to inulin particles creating a targeted drug delivery system. This system will transport drugs specifically to afflicted areas, reducing systemic concentrations of drugs and h ....Drug Targeting to Immune Cells Using Modified Inulin Particles. Vaxine Pty Ltd is an Australian biotechnology company that has discovered specific particulate forms of inulin that are efficiently internalised by human immune cells. This project aims to exploit cell migration to injury and infection sites by attaching drugs to inulin particles creating a targeted drug delivery system. This system will transport drugs specifically to afflicted areas, reducing systemic concentrations of drugs and hence the risks of dose related side effects. This project has potential both to improve healthcare and to encourage the growth of expertise in the biotechnology industry in Australia.Read moreRead less
Superior Australian psyllium for functional foods. This project aims to establish a breeding program for Plantago ovata in Australia to provide a reliable supply of high quality, superior psyllium as a key ingredient in the gluten-free food industry, providing benefits to the industrial partner, growers in Australia and consumers. Target traits include better harvest index, reduced seed shattering and identification of lines carrying psyllium with novel properties or whole seeds that can be grou ....Superior Australian psyllium for functional foods. This project aims to establish a breeding program for Plantago ovata in Australia to provide a reliable supply of high quality, superior psyllium as a key ingredient in the gluten-free food industry, providing benefits to the industrial partner, growers in Australia and consumers. Target traits include better harvest index, reduced seed shattering and identification of lines carrying psyllium with novel properties or whole seeds that can be ground and used as flour that imparts less intense colour changes or effects on loaf structure, and which may be highly suitable for other baked gluten-free products. The fundamental knowledge gained from the genetic and biochemical anlayses of these lines will also broadly benefit seed biology research.Read moreRead less
Evaluating the applicability of Directed Evolution to the optimisation of industrial yeast strains. The fermentation industries, particularly the wine industry, are of great economic importance to Australia. Wine exports exceed $2 billion per year. Moreover, the industry and those supporting it are major employers in regional Australia. To maintain and grow our share of the international market, Australian wine must remain competitive by increasing production efficiency, maximizing quality and k ....Evaluating the applicability of Directed Evolution to the optimisation of industrial yeast strains. The fermentation industries, particularly the wine industry, are of great economic importance to Australia. Wine exports exceed $2 billion per year. Moreover, the industry and those supporting it are major employers in regional Australia. To maintain and grow our share of the international market, Australian wine must remain competitive by increasing production efficiency, maximizing quality and keeping up with changing consumer preferences, and with minimal environmental impact. As a cornerstone to the winemaking process, the yeast is a vehicle for achieving these needs. This project will develop and evaluate a method for generation of unique yeast which are non-recombinant and which yield superior wine under modern winemaking conditions.Read moreRead less