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Novel Microdevices For Controlled Blood And Skin Extraction
Funder
National Health and Medical Research Council
Funding Amount
$314,644.00
Summary
Current blood sampling devices only create a puncture in the skin but have no capacity to collect blood while current tissue biopsies are not capable of repeated sampling in patients without the need for local anaesthesia or sutures. There is a need for clinically feasible devices to enable preventive strategies in the area of skin cancer and communicable diseases through facilitation of early detection, particularly in rural/remote areas where medical resources are limited.
Synthetic Approaches For Dissection Of The Signalling Response Heterogeneity And Targeted Therapeutic Use Of Type-1 Interferons
Funder
National Health and Medical Research Council
Funding Amount
$375,974.00
Summary
Type-1 interferons have been used to treat at least 14 diseases, including cancer, hepatitis and multiple sclerosis. Differing success of treatment and serious side effects felt by patients, however, have limited use of these otherwise powerful therapies. I aim to better understand the responses different cells have to interferons to improve their utility in the clinic. Also, I will develop approaches to target interferons to the site of disease, reducing the side effects felt by patients.