Nanoscale heating towards high efficient nitrogen reduction reduction. This project aims to develop nanoscale heating technique using AC magnetic field for efficient synthesis of ammonia, widely used for fertiliser and having potential for hydrogen storage. This project is to introduce nanoscale heating concept by heating catalyst only but not solution in electrochemical catalysis to achieve high catalytic activity. Expected outcome is the creation of low cost catalysts having high selectivity a ....Nanoscale heating towards high efficient nitrogen reduction reduction. This project aims to develop nanoscale heating technique using AC magnetic field for efficient synthesis of ammonia, widely used for fertiliser and having potential for hydrogen storage. This project is to introduce nanoscale heating concept by heating catalyst only but not solution in electrochemical catalysis to achieve high catalytic activity. Expected outcome is the creation of low cost catalysts having high selectivity and formation rate for ammonia production. This unique technology has the potential to replace current ammonia production based on Haber-Bosch process, which consumes 2% of world energy and contributes 3% of overall CO2 emission. The project provides opportunities for new industries that will benefit Australian economy.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE170100137
Funder
Australian Research Council
Funding Amount
$358,275.00
Summary
Integrated thin film facility for catalysis and energy materials research. This project aims to establish thin film fabrication with catalytic/gas sorption characterisation needed for energy research. This project will overcome current limitations in advanced energy materials design via wet chemical methods. It will enable materials synthesis and characterisation toward thermal/photo/electro-catalytic, hydrogen storage, and battery technologies. The facility is expected to drive fundamental conc ....Integrated thin film facility for catalysis and energy materials research. This project aims to establish thin film fabrication with catalytic/gas sorption characterisation needed for energy research. This project will overcome current limitations in advanced energy materials design via wet chemical methods. It will enable materials synthesis and characterisation toward thermal/photo/electro-catalytic, hydrogen storage, and battery technologies. The facility is expected to drive fundamental concepts, and enable combinatorial search and new thin film technology. It is anticipated that this facility will increase Australia’s international competitiveness in the development of advanced energy materials.Read moreRead less
Commercial scale production of biocrude by hydrothermal liquefaction. The project aims to develop new understanding and tools to support commercial-scale production of biocrude from microalgae or biosolids and enable a breakthrough in cost-effective production of sustainable fuels. A novel hydrothermal liquefaction reactor has been developed that has strong potential to overcome the limitations of Muradel's existing demonstration reactor which, while world-leading, is uneconomical at commercial ....Commercial scale production of biocrude by hydrothermal liquefaction. The project aims to develop new understanding and tools to support commercial-scale production of biocrude from microalgae or biosolids and enable a breakthrough in cost-effective production of sustainable fuels. A novel hydrothermal liquefaction reactor has been developed that has strong potential to overcome the limitations of Muradel's existing demonstration reactor which, while world-leading, is uneconomical at commercial scale. The project aims to develop design tools to optimise the new reactor, comprising a chemical model of the complex, multi-component hydrothermal liquefaction reactions, a computational model of the mixing and heat transfer within it and a network model of the energy and exergy flows.Read moreRead less
Development of Pyrrolopyrimidines as Inhibitors of ATP-Binding Proteins. This project seeks to generate analogues of natural products that have been found to be active against cancer cells and tropical parasites. The new materials produced by this project will aid in the study of biochemical processes involved in diseases such as cancer and lymphatic filariasis, thus leading the way to development of these compounds as potential treatments for such diseases.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0882289
Funder
Australian Research Council
Funding Amount
$520,000.00
Summary
New generation mass spectrometers for characterisation of molecular shape and size. The ion mobility mass spectrometer (IMMS at UOW) will be the first of its kind in Australia, and together with the ion trap mass spectrometer (ITMS at ANU) will continue the tradition of this partnership in providing researchers with cutting-edge instrumentation for nationally and internationally important projects including: (i) fundamental understanding of the ways in which biomolecules recognize one another, ( ....New generation mass spectrometers for characterisation of molecular shape and size. The ion mobility mass spectrometer (IMMS at UOW) will be the first of its kind in Australia, and together with the ion trap mass spectrometer (ITMS at ANU) will continue the tradition of this partnership in providing researchers with cutting-edge instrumentation for nationally and internationally important projects including: (i) fundamental understanding of the ways in which biomolecules recognize one another, (ii) investigating the structure(s) of lipids (fats) in cardiovascular disease and cataract, (iii) developing anticancer drugs, and (iv) development of new materials.Read moreRead less
ARC Centre of Excellence for the Mathematical Analysis of Cellular Systems. ARC Centre of Excellence for the Mathematical Analysis of Cellular Systems. The ARC Centre for the Mathematical Analysis of Cellular Systems aims to deliver the mathematics required to compute life. The Centre will deliver innovation in computational and mathematical biology and establish in silico biology alongside in vivo and in vitro biology. These models will allow us to understand the complexity of life at the cellu ....ARC Centre of Excellence for the Mathematical Analysis of Cellular Systems. ARC Centre of Excellence for the Mathematical Analysis of Cellular Systems. The ARC Centre for the Mathematical Analysis of Cellular Systems aims to deliver the mathematics required to compute life. The Centre will deliver innovation in computational and mathematical biology and establish in silico biology alongside in vivo and in vitro biology. These models will allow us to understand the complexity of life at the cellular level and enable new ways of combining diverse and heterogenous data. This will allow us to understand the mechanisms underlying cellular behaviour, and to apply rational design engineering methods in order to control the dynamics of biological systems. Read moreRead less
Androgen receptor: A master regulator of lipid metabolism. This project aims to understand how male sex hormones, or androgens, affect the amount and metabolism of fats in normal body tissues. By integrating our multi-disciplinary expertise in androgen action, molecular biology, metabolism and bioinformatics with novel techniques and instrumentation, this collaboration expects to generate the first detailed picture of how fat metabolism is controlled by androgens in humans, and how closely this ....Androgen receptor: A master regulator of lipid metabolism. This project aims to understand how male sex hormones, or androgens, affect the amount and metabolism of fats in normal body tissues. By integrating our multi-disciplinary expertise in androgen action, molecular biology, metabolism and bioinformatics with novel techniques and instrumentation, this collaboration expects to generate the first detailed picture of how fat metabolism is controlled by androgens in humans, and how closely this relates to mice. Expected outcomes and benefits will be a new understanding of which aspects of fat metabolism are most influenced by androgens, and an ability to anticipate potential metabolic impacts of natural or pharmacological fluctuations in androgen levels in humans, laboratory animals and livestock.Read moreRead less
Computational methods for population-size-dependent branching processes. Branching processes are the primary mathematical tool used to model populations that evolve randomly in time. Most key results in the theory are derived under the simplifying assumption that individuals reproduce and die independently of each other. However, this assumption fails in most real-life situations, in particular when the environment has limited resources or when the habitat has a restricted capacity. This project ....Computational methods for population-size-dependent branching processes. Branching processes are the primary mathematical tool used to model populations that evolve randomly in time. Most key results in the theory are derived under the simplifying assumption that individuals reproduce and die independently of each other. However, this assumption fails in most real-life situations, in particular when the environment has limited resources or when the habitat has a restricted capacity. This project aims to develop novel and effective algorithmic techniques and statistical methods for a class of branching processes with dependences. We will use these results to study significant problems in the conservation of endangered island bird populations in Oceania, and to help inform their conservation management.Read moreRead less
A Novel Geometric Approach to Shocks in Reaction-Nonlinear Diffusion Models. Reaction-nonlinear diffusion models play a vital role in the study of cell migration and population dynamics. However, the presence of aggregation, or backward diffusion, leads to the formation of shock waves - distinct, sharp interfaces between different populations of densities of cells - and the breakdown of the model. This project will develop new geometric methods to explain the formation and temporal evolution of ....A Novel Geometric Approach to Shocks in Reaction-Nonlinear Diffusion Models. Reaction-nonlinear diffusion models play a vital role in the study of cell migration and population dynamics. However, the presence of aggregation, or backward diffusion, leads to the formation of shock waves - distinct, sharp interfaces between different populations of densities of cells - and the breakdown of the model. This project will develop new geometric methods to explain the formation and temporal evolution of these shock waves, while simultaneously unifying existing regularisation techniques under a single, geometric banner. It will devise innovative tools in singular perturbation theory and stability analysis that will identify key parameters in the creation of shock waves, as well as their dynamic behaviour.Read moreRead less
Rejuvenating adult stem cells. This project aims to uncover intimate links between metabolic regulation and longevity in adult stem cells, the source of all cells in the body. Understanding why we age and whether ageing is preventable are research challenges which must be first attacked at a cellular level. This project will try to rejuvenate aged stem cells by interfering with a prospective molecular master switch of aging and also develop an approach to identify and select youthful stem cells. ....Rejuvenating adult stem cells. This project aims to uncover intimate links between metabolic regulation and longevity in adult stem cells, the source of all cells in the body. Understanding why we age and whether ageing is preventable are research challenges which must be first attacked at a cellular level. This project will try to rejuvenate aged stem cells by interfering with a prospective molecular master switch of aging and also develop an approach to identify and select youthful stem cells. The results are expected to be important beyond informing the science of ageing, in the areas of tissue engineering, wound healing, embryology and cancer.Read moreRead less