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A Scalable Insomnia Program During The Pregnancy And Postpartum Periods: An Effectiveness-Implementation Hybrid Trial
Funder
National Health and Medical Research Council
Funding Amount
$877,335.00
Summary
Persistent sleep problems are common during pregnancy/postpartum periods and have significant consequences. Cognitive behavioural interventions are efficacious for improving sleep but are not currently available in perinatal care. This study examines the effectiveness, cost- effectiveness, and implementation potential of an innovative nonpharmacological intervention for better maternal sleep and wellbeing, with high potential for sustainable integration with routine perinatal care.
A Large-scale Clinical Effectiveness (health Services) Trial To Determine Whether Personalised Health Care Packages, Combined With Digitally-supported Measurement-based Care, Improve Functional Outcomes In Young People With Mood Disorders
Funder
National Health and Medical Research Council
Funding Amount
$3,434,588.00
Summary
One of our greatest current health challenges is to develop highly-personalised interventions for teenagers and young adults with emerging mood disorders. This research will combine our national expertise to develop and implement care packages utilising digital technologies, personalised assessment techniques, targeted treatment choices, and long-term outcome tracking. In a clinical trial we will assess the clinical effectiveness of these innovative healthcare packages.
Breathing Control As A Treatment For Non-Epileptic Seizures
Funder
National Health and Medical Research Council
Funding Amount
$1,740,186.00
Summary
Non-epileptic Seizures (NES) are fits that look like epilepsy but are not, and are instead thought to be a psychological response to problems. Treating them psychologically is difficult, however, and doesn't usually work. We have discovered that patients' fits involve hyperventilation, like a panic attack, and can be stopped by teaching them to control their breathing in a similar way. In this study we aim to prove this, by completing a trial of breath control training in NES.
A Randomised Controlled Trial Of N-acetylcysteine For The Treatment Of Alcohol Use Disorder
Funder
National Health and Medical Research Council
Funding Amount
$1,294,923.00
Summary
We urgently require new treatment strategies. Alcohol misuse is a leading cause of preventable death yet treatment options are limited. We will undertake the first human trial of N-acetylcysteine (NAC) for the management of alcohol use disorder (NAC-AUD). The NAC-AUD project will evaluate the efficacy and cost-efficacy of NAC to reduce alcohol consumption. The results will generate high level clinical evidence for a safe new treatment for a common life threatening disease.