Discovery and characterisation of novel spider-venom peptides targeting the human sodium ion channel Nav1.7. Drugs that selectively block the human sodium ion channel Nav1.7 are likely to be powerful analgesics for treating a wide variety of pain conditions. However, it has proved difficult to obtain selective blockers of this channel. The aim of this project is to determine whether spider-venoms might provide a source of highly selective Nav1.7 blockers.
Indonesian Democracy: The Politics of Failed Reform and Regime Viability. Despite high hopes following the fall of Indonesia's authoritarian regime, political reform has been limited. The project examines the reasons for slow progress. Among the areas to be studied are constitutional and electoral reform, military reform, judicial reform, decentralisation, preservation of order and economic reform. It will argue that the weakness of the state in carrying out reforms is largely due to the penetra ....Indonesian Democracy: The Politics of Failed Reform and Regime Viability. Despite high hopes following the fall of Indonesia's authoritarian regime, political reform has been limited. The project examines the reasons for slow progress. Among the areas to be studied are constitutional and electoral reform, military reform, judicial reform, decentralisation, preservation of order and economic reform. It will argue that the weakness of the state in carrying out reforms is largely due to the penetration of the state itself by vested interests. Limited reforms have only been implemented when the viability of the regime itself has been at stake. This research is significant for Indonesian politics and political theory.Read moreRead less
Strategic assessment of research performance indicators. The use of quantitative measures of research performance in higher education sends powerful messages to those being evaluated, because the choice of measures signals what is considered most important. However, little critical assessment has been undertaken on the use of performance indicators or their impact on research practice. This project will create a knowledge base on performance measures - their validity, fairness, transparency and ....Strategic assessment of research performance indicators. The use of quantitative measures of research performance in higher education sends powerful messages to those being evaluated, because the choice of measures signals what is considered most important. However, little critical assessment has been undertaken on the use of performance indicators or their impact on research practice. This project will create a knowledge base on performance measures - their validity, fairness, transparency and impact on research, and the cost of implementation. By assessing an extensive range of measures, it will provide Australian science management and science policy makers with rigorous information on which to base informed judgements on their utilisation.Read moreRead less
Impact of evaluation-based funding on the content of scientific research. Evidence suggests that evaluation-based funding mechanisms trigger adaptive behaviour in scientists, leading to unintended changes in knowledge production. However, there is no conclusive evidence about when (under what circumstances), how (by what processes) and with what effects researchers adapt to these mechanisms. This study aims to answer these crucial questions. To overcome the methodological weaknesses of earlier s ....Impact of evaluation-based funding on the content of scientific research. Evidence suggests that evaluation-based funding mechanisms trigger adaptive behaviour in scientists, leading to unintended changes in knowledge production. However, there is no conclusive evidence about when (under what circumstances), how (by what processes) and with what effects researchers adapt to these mechanisms. This study aims to answer these crucial questions. To overcome the methodological weaknesses of earlier studies, a comparative investigation of several research fields and universities will be conducted, combining for the first time: qualitative interviews, ethnographic observations and bibliometric studies. It will enhance Australian research policy with a critical assessment of existing research funding models.Read moreRead less
'Political' public servants: challenges, risks and rewards. The current ministerial and parliamentary staff system in Australia, established by the Member of Parliament Staff Act 1984, created a mechanism by which public servants can disengage from the public service while working as ministerial and parliamentary staffers, and later re-engage with the public service. This project will explore the phenomenon of the so-called 'political public servant' and the nature of impartiality and partisansh ....'Political' public servants: challenges, risks and rewards. The current ministerial and parliamentary staff system in Australia, established by the Member of Parliament Staff Act 1984, created a mechanism by which public servants can disengage from the public service while working as ministerial and parliamentary staffers, and later re-engage with the public service. This project will explore the phenomenon of the so-called 'political public servant' and the nature of impartiality and partisanship, asking whether these attributes are easily adopted and discarded or whether in fact they coexist within a subset of 'hybrid' public servants.Read moreRead less
Evaluating the impact of neuromusculoskeletal impairment on athletic performance. Sufficient physical activity is required for good health. Competitive sport is a culturally significant physical activity in Australia and the prospect of participating in fair competition is known to drive participation. In Paralympic sport, fair competition is enabled by classification, which aims to minimise the impact of impairments on competition outcome. Unfortunately classification methods are not evidence-b ....Evaluating the impact of neuromusculoskeletal impairment on athletic performance. Sufficient physical activity is required for good health. Competitive sport is a culturally significant physical activity in Australia and the prospect of participating in fair competition is known to drive participation. In Paralympic sport, fair competition is enabled by classification, which aims to minimise the impact of impairments on competition outcome. Unfortunately classification methods are not evidence-based, reducing confidence in the process and discouraging participation. This project will inform the development of the first evidence-based classification system, creating the possibility that, in the future, the prospect of truly fair competition may motivate sports participation among Australians, regardless of disability.Read moreRead less
Deliberative democracy in the public sphere: achieving deliberative outcomes in mass publics. This project will systematically explore ways in which citizens can engage more deeply with complex policy issues without the need to resort to massive expenditure on running multiple deliberative forums, such as citizens' assemblies. It will identify the language is needed to deliberatively inform and the vehicles for providing that information.
Responding to Globalization: Firms, the State and Upgrading in the Automotive Industry on the Western Pacific Rim. The automotive industry is arguably still the most important manufacturing sector in the world economy. It is one of the most 'globalized' of industrial sectors, whether considered in terms of geographical dispersion of production or of trade. In Australia, the turnover of the auto industry is around $17 billions per year. It employs more than 50,000 people. Like other auto industri ....Responding to Globalization: Firms, the State and Upgrading in the Automotive Industry on the Western Pacific Rim. The automotive industry is arguably still the most important manufacturing sector in the world economy. It is one of the most 'globalized' of industrial sectors, whether considered in terms of geographical dispersion of production or of trade. In Australia, the turnover of the auto industry is around $17 billions per year. It employs more than 50,000 people. Like other auto industries around the region, that in Australia must adjust to several rapidly changing contexts driven by technological developments, industry consolidation, and new trade regimes. This project will provide a better understanding of the forces driving change, and of the range of possible policy responses available to firms and governments.Read moreRead less
Democratic Audit of Australia. The Democratic Audit of Australia is an assessment of Australia's strengths and weaknesses as a democratic society. It will examine five key areas: (i) citizenship, law and rights; (2) representative and accountable government; (3) participation and government responsiveness; (4) democracy beyond the state; and (5) democracy and federalism. The audit process was pioneered in Britain and has now been applied in ten countries including New Zealand.
The Audit aim ....Democratic Audit of Australia. The Democratic Audit of Australia is an assessment of Australia's strengths and weaknesses as a democratic society. It will examine five key areas: (i) citizenship, law and rights; (2) representative and accountable government; (3) participation and government responsiveness; (4) democracy beyond the state; and (5) democracy and federalism. The audit process was pioneered in Britain and has now been applied in ten countries including New Zealand.
The Audit aims to make a major methodological contribution to democracy assessment, as well as providing benchmark data for purposes of monitoring and international comparison. It will also promote public debate over democracy issues.Read moreRead less
Democratic Audit of Australia: The Second Wave. The Democratic Audit asks "How democratic is our country and its government?" This project will give the community a comprehensive survey of the strengths and weaknesses of Australian democracy, tracking changes since the 2004 report. It will also provide more detailed findings on major questions that confront Australian governments now like the regulation of political financing and the impact on politics of new technologies like the internet. Usin ....Democratic Audit of Australia: The Second Wave. The Democratic Audit asks "How democratic is our country and its government?" This project will give the community a comprehensive survey of the strengths and weaknesses of Australian democracy, tracking changes since the 2004 report. It will also provide more detailed findings on major questions that confront Australian governments now like the regulation of political financing and the impact on politics of new technologies like the internet. Using audit data, the project will produce a major scholarly analysis of the relationship between democratic values and the institutional choices made in Australia. Because a central objective of the Audit is to promote public debate, all Audit findings are published and placed on the Audit website.Read moreRead less