Discovery and characterisation of novel spider-venom peptides targeting the human sodium ion channel Nav1.7. Drugs that selectively block the human sodium ion channel Nav1.7 are likely to be powerful analgesics for treating a wide variety of pain conditions. However, it has proved difficult to obtain selective blockers of this channel. The aim of this project is to determine whether spider-venoms might provide a source of highly selective Nav1.7 blockers.
Indonesian Democracy: The Politics of Failed Reform and Regime Viability. Despite high hopes following the fall of Indonesia's authoritarian regime, political reform has been limited. The project examines the reasons for slow progress. Among the areas to be studied are constitutional and electoral reform, military reform, judicial reform, decentralisation, preservation of order and economic reform. It will argue that the weakness of the state in carrying out reforms is largely due to the penetra ....Indonesian Democracy: The Politics of Failed Reform and Regime Viability. Despite high hopes following the fall of Indonesia's authoritarian regime, political reform has been limited. The project examines the reasons for slow progress. Among the areas to be studied are constitutional and electoral reform, military reform, judicial reform, decentralisation, preservation of order and economic reform. It will argue that the weakness of the state in carrying out reforms is largely due to the penetration of the state itself by vested interests. Limited reforms have only been implemented when the viability of the regime itself has been at stake. This research is significant for Indonesian politics and political theory.Read moreRead less
Data-driven monitoring of raceway dynamics in ironmaking blast furnaces. Raceway dynamics in ironmaking blast furnaces affect operational stability and cost considerably, yet their dynamic behaviour has not been well monitored online. The project aims to develop a data-driven model for monitoring the internal state of gas-solid-powder reacting flow in the raceway and predicting raceway anomalies online. It will be achieved by combining particle-fluid numerical simulations with data processing an ....Data-driven monitoring of raceway dynamics in ironmaking blast furnaces. Raceway dynamics in ironmaking blast furnaces affect operational stability and cost considerably, yet their dynamic behaviour has not been well monitored online. The project aims to develop a data-driven model for monitoring the internal state of gas-solid-powder reacting flow in the raceway and predicting raceway anomalies online. It will be achieved by combining particle-fluid numerical simulations with data processing and reduced-order state observer, supported by lab/plant experiments, and collaborating with two industry partners from coal and steel industries. The project outcomes including codes, models and raceway control strategies can help promote Australian metallurgical coal's global markets and ultimately the Australian economy.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE240100131
Funder
Australian Research Council
Funding Amount
$539,000.00
Summary
Federated Omniverse Facilities for Smart Digital Futures. A world-first trans-disciplinary, -domain, and -institutional smart 3D omniverse R&D ecosystem AuVerse will be built in NSW, affiliated with Queensland, and accessible to academia and industry. AuVerse will support cloud-based, reality-virtuality-fused, immersive, interactive and secure future-oriented digital design, development, training and society. In the new era of digital innovation and paradigm shift, AuVerse will substantially boo ....Federated Omniverse Facilities for Smart Digital Futures. A world-first trans-disciplinary, -domain, and -institutional smart 3D omniverse R&D ecosystem AuVerse will be built in NSW, affiliated with Queensland, and accessible to academia and industry. AuVerse will support cloud-based, reality-virtuality-fused, immersive, interactive and secure future-oriented digital design, development, training and society. In the new era of digital innovation and paradigm shift, AuVerse will substantially boost Australia’s pivotal research leadership and business competitiveness in nurturing new-generation, collaborative and transformative digital R&D and talent pipeline. It will enable large-scale strategic business innovation and transformation including smart manufacturing and Industry 4.0.Read moreRead less
Expectations and commitments in the Australia-USA alliance. This project aims to investigate the gap between the high expectations of mutual support and the lack of detailed security commitments in the Australia-US Alliance. The project intends to use a focused approach that captures thematic aspects of the alliance through project frames and historical slices across time. Expected outcomes can advance understanding of how alliances operate as security institutions. The outcomes can help to prom ....Expectations and commitments in the Australia-USA alliance. This project aims to investigate the gap between the high expectations of mutual support and the lack of detailed security commitments in the Australia-US Alliance. The project intends to use a focused approach that captures thematic aspects of the alliance through project frames and historical slices across time. Expected outcomes can advance understanding of how alliances operate as security institutions. The outcomes can help to promote a more informed national conversation about the costs and benefits of Australia's security relationship with the United States of America (USA) and contribute to debates over the future of the Australia-USA Alliance during a period of strategic uncertainty.Read moreRead less
New Lead-Free Brass Solutions for Drinking Water Applications. The aim of this Linkage Project is to provide viable material solutions to address the health problem of Lead-contamination in drinking water arising from Leaded-brass plumbing products and the impact Lead-removal from brass will have on the brass industry. In order to achieve this, this project engages leading multidisciplinary researchers along with Australian and international industry partners from across the brass industry suppl ....New Lead-Free Brass Solutions for Drinking Water Applications. The aim of this Linkage Project is to provide viable material solutions to address the health problem of Lead-contamination in drinking water arising from Leaded-brass plumbing products and the impact Lead-removal from brass will have on the brass industry. In order to achieve this, this project engages leading multidisciplinary researchers along with Australian and international industry partners from across the brass industry supply and sales network. This project seeks to identify and harness the key material-product attributes required to develop and implement new, lead-free alloy alternatives that meet health-compliance, production and commercial viability, that offer benefits across the industry network and health benefits to society.Read moreRead less
Special Research Initiatives - Grant ID: SR200200739
Funder
Australian Research Council
Funding Amount
$202,156.00
Summary
Monitoring Deliberative Integrity in Australia. The project aims to develop and apply the concept of deliberative integrity as a counterpart to more familiar ideas about electoral integrity in the evaluation of democratic processes. The project develops significant new knowledge about the ethical conduct of Australian citizen engagement processes through conceptual and methodological innovation to produce a Deliberative Integrity Monitoring Tool that will be applied to the expanding range of del ....Monitoring Deliberative Integrity in Australia. The project aims to develop and apply the concept of deliberative integrity as a counterpart to more familiar ideas about electoral integrity in the evaluation of democratic processes. The project develops significant new knowledge about the ethical conduct of Australian citizen engagement processes through conceptual and methodological innovation to produce a Deliberative Integrity Monitoring Tool that will be applied to the expanding range of deliberative democratic innovations in Australia. Expected outcomes include a better understanding of how such innovations can and should be designed. Benefits include a set of standards for best practice in democratic innovation that will in turn help improve the quality of Australian democracy.Read moreRead less
Strategic assessment of research performance indicators. The use of quantitative measures of research performance in higher education sends powerful messages to those being evaluated, because the choice of measures signals what is considered most important. However, little critical assessment has been undertaken on the use of performance indicators or their impact on research practice. This project will create a knowledge base on performance measures - their validity, fairness, transparency and ....Strategic assessment of research performance indicators. The use of quantitative measures of research performance in higher education sends powerful messages to those being evaluated, because the choice of measures signals what is considered most important. However, little critical assessment has been undertaken on the use of performance indicators or their impact on research practice. This project will create a knowledge base on performance measures - their validity, fairness, transparency and impact on research, and the cost of implementation. By assessing an extensive range of measures, it will provide Australian science management and science policy makers with rigorous information on which to base informed judgements on their utilisation.Read moreRead less