Repeat Expansions In Neurological Disease: Discovery, Interpretation And Enhanced Diagnostics
Funder
National Health and Medical Research Council
Funding Amount
$889,937.00
Summary
Identifying the mutation or genetic cause of disease in an individual is the first step in the provision of appropriate clinical care and treatment. This diagnostic process is being revolutionised through the ability to sequence the entire human genome in a time and cost effective manner. This project will enable identification of novel and known repeat expansion using whole genome sequencing, providing rapid diagnoses and better clinical care for individuals with neurogenetic disorders.
Using Novel Point-of-care Diagnostic Tests And Mathematical Modelling To Achieve Hepatitis B Elimination: The Rapid B Study
Funder
National Health and Medical Research Council
Funding Amount
$381,948.00
Summary
Liver cancer is increasing rapidly in Australia and globally and depite hepatitis B virus infection being the leading cause, treatment rates are low. We have developed innovative point-of-care blood tests that use a single droplet of blood to measure liver damage, that will help overcome barriers to treatment uptake worldwide. The Rapid B Study will use mathematical modelling to investigate the most cost-effective way to combine these novel tests with treatment to reduce liver cancer deaths.