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Increasing Knowledge Of Mental And Physical Harms Among People Who Inject Drugs
Funder
National Health and Medical Research Council
Funding Amount
$88,502.00
Summary
People who inject drugs (PWID) commonly experience a range of health problems. These include injecting-related injuries and non-viral diseases (e.g. endocarditis), drug overdose and mental health problems. With a focus on reducing the presence of these harms among the injecting population, the proposed research aims to better understand the factors that contribute to PWID experiencing, or not experiencing, such harms.
Investigations Into The Aetiology Of Giant Cell Arteritis
Funder
National Health and Medical Research Council
Funding Amount
$165,067.00
Summary
Despite much research the precise pathoetiology of giant cell arteritis is poorly understood. Both environmental and genetic factors are thought to contribute to disease development. Though to date, no overriding mechanism for disease development has been identified. This research will apply modern molecular techniques to further explore the pathogenic processes in this devastating disease which in turn will hopefully provide insight into novel treatment modalities.
The Significance Of Aeroallergens In Eosinophilic Esophagitis
Funder
National Health and Medical Research Council
Funding Amount
$117,331.00
Summary
Eosinophilic esophagitis is an allergic condition that causes difficulty swallowing food and chest discomfort.Current diagnostic methods are inaccurate, and treatments are not curative. This project aims to clarify the role of promising new diagnostic techniques and to delineate the significance of aeroallergens (e.g. pollens) with a view to improving the treatment of eosinophilc esophagitis in the future. It is possible that simply avoiding pollens or treating hayfever in the future may be all ....Eosinophilic esophagitis is an allergic condition that causes difficulty swallowing food and chest discomfort.Current diagnostic methods are inaccurate, and treatments are not curative. This project aims to clarify the role of promising new diagnostic techniques and to delineate the significance of aeroallergens (e.g. pollens) with a view to improving the treatment of eosinophilc esophagitis in the future. It is possible that simply avoiding pollens or treating hayfever in the future may be all that is required to manage this condition.Read moreRead less
SMARTphone-Based Cardiovascular Risk Reduction In BREAST Cancer Patients
Funder
National Health and Medical Research Council
Funding Amount
$88,662.00
Summary
Heart disease is a leading cause of death in patients with breast cancer. Physical exercise during cancer treatment has been shown to improve overall survival by reducing future problems with the heart as well as recurrence of the cancer. Despite this, few women achieve the guideline recommended target for exercise. This study will test a Smartphone application called 'BreastMate' which is designed to promote physical activity and heart health in patients with breast cancer.
Vitamin D And Chronic Kidney Disease: The Effects On Mineral Metabolism, Vascular Calcification And Transplant Outcomes
Funder
National Health and Medical Research Council
Funding Amount
$103,582.00
Summary
Kidney disease is a major health issue in the community. Vitamin D deficiency has been associated with an increased burden of cardiovascular disease and mortality in these patients. Vitamin D also has been shown to have a significant role in modulating our immune system. This study aims to assess the potential of vitamin D therapy to reduce the burden of cardiovascular disease and its effects on the immune function of renal transplant recipients in the laboratory and clinical setting.
Understanding The Unique Contribution Of Sedentary Behaviour To The Cardio Metabolic Health Of Women
Funder
National Health and Medical Research Council
Funding Amount
$83,149.00
Summary
The risk of heart disease for women increases significantly with the menopause. New evidence suggests that sedentary behaviour (too much sitting as distinct from too little exercise) is also related to heart disease risk. Ms Howard's PhD research will identify whether TV time and other prolonged sitting pose a particular risk for women during and after the menopause. Her studies will identify whether there is a need for women's health recommendations on reducing sitting time.
The aim of this project is to investigate the burden which is caused by diabetes in people with coronary heart disease, and to determine whether the risk associated with diabetes has increased in recent years. This project will measure the magnitude of this problem, to assist with decision-making about allocation of health resources. The findings will also allow doctors to identify the risk of future acute cardiovascular events such as a heart attack which are associated with having diabetes.
Increasing The Efficacy Of Web-based Physical Activity Interventions: Improving Website Promotion And Participant Engagement
Funder
National Health and Medical Research Council
Funding Amount
$62,073.00
Summary
This project aims to test innovative ways to improve web-based physical activity interventions able to reach large numbers of Australians at low-cost. In particular the effectiveness of internet promotion, personally tailored advice in video format and a brief Skype counseling session will be tested. Findings will inform the next generation of interventions that have the ability to improve physical activity levels in a large number of Australians and reduce the prevalence of disease.
Factors That Influence Disease Severity In Tuberculosis
Funder
National Health and Medical Research Council
Funding Amount
$149,076.00
Summary
Tuberculosis (TB) is a major global health problem and is one of the leading causes of death from an infectious disease worldwide. The severity of disease that occurs with TB is dependent on many complex factors including the infected person’s immune system and factors related to the TB organism itself. This research will determine the key factors that cause severe disease in TB which will translate into improved care of TB patients and enhance further research in this field.
Evaluating The Effectiveness Of Interventions To Reduce Population Salt Intake
Funder
National Health and Medical Research Council
Funding Amount
$84,800.00
Summary
Eating too much salt is estimated to cause nearly 1 of every 5 heart disease deaths before the age of 70. Almost all people eat too much salt causing high blood pressure. Although health leaders recommend all countries to reduce salt eaten to prevent deaths, there is uncertainty about which initiatives are more effective in getting people to eat less salt. This study will address this by assessing how effective the initiatives in Fiji, Samoa & Victoria are in reducing salt eaten and salt in food