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Metabolic And Molecular Basis Of Embryo Signalling
Funder
National Health and Medical Research Council
Funding Amount
$409,836.00
Summary
Cells in the body are powered by mitochondria that essentially generate the energy required for development. This grant will determine how the environment affects the mitochondria in the developing embryo and determine the impacts to the embryo and pregnancy if a mitochondria is partially shut down.
Improving Oocyte Mitochondrial DNA Copy Number To Enhance Female Reproductive Capacity.
Funder
National Health and Medical Research Council
Funding Amount
$670,867.00
Summary
Eggs with too few copies of mitochondrial DNA either fail to fertilise or arrest during early development. By supplementing eggs with mitochondrial DNA, we have been able to enhance embryo quality and gene expression profiles. By breeding the offspring derived from eggs given mitochondrial supplementation, we will determine if they and their progeny meet normal developmental milestones, regulate the transmission of mitochondrial DNA appropriately, and are healthy and fertile.
Health And Fertility Of Young Men Conceived Using Intra-cytoplasmic Sperm Injection
Funder
National Health and Medical Research Council
Funding Amount
$362,570.00
Summary
The injection of a single sperm into the egg (ICSI) has been the main IVF treatment for men with poor sperm quality since 1993 but is now often used for other types of infertility. Concern has been raised about the health of the children. We will approach >800 parents and their adult sons conceived using ICSI and will assess his general health and development, and fertility. This work will improve patient counselling and practice guidelines, and direct research into the safety of ICSI.
Clinical Review Of A Cohort Aged 22-33 Years Conceived Using Assisted Reproductive Technologies
Funder
National Health and Medical Research Council
Funding Amount
$946,454.00
Summary
In a recent study, using telephone-interviews, we compared the health and wellbeing of 547 singleton young adults born following assisted reproductive technologies (ART), with 549 matched controls. Reviewing their health when they are 22-33 years is possible because of their ongoing interest. We have a protocol in place to measure their cardiac and respiratory function and other aspects of growth and development. Our findings will fill a major knowledge gap about the longer term safety of ART.
A Baroque Archbishop in colonial Australia: James Goold (1812-1886). This project aims to investigate the cultural vision of the first Catholic Archbishop of Melbourne, James Goold (1812-1886), whose architectural patronage changed Melbourne. An Irishman educated in Italy, Goold was a passionate collector and missionary bishop. He imported a library and late Italian Baroque paintings to convey the intensity of European religious experience. When Goold was appointed to Melbourne, it was a provinc ....A Baroque Archbishop in colonial Australia: James Goold (1812-1886). This project aims to investigate the cultural vision of the first Catholic Archbishop of Melbourne, James Goold (1812-1886), whose architectural patronage changed Melbourne. An Irishman educated in Italy, Goold was a passionate collector and missionary bishop. He imported a library and late Italian Baroque paintings to convey the intensity of European religious experience. When Goold was appointed to Melbourne, it was a provincial town, but the discovery of gold and the commissioning of St Patrick's Cathedral made Melbourne an international metropolis. The project will examine Goold’s collection and communicate the results through an exhibition and conference. The research may change our understanding of the narratives of Colonial Australia.Read moreRead less
Eurasian exchange and artistic transformation in art. This project aims to bring European and Chinese art history into dialogue. It explores the early Italian Renaissance in the larger geopolitical context of Mongol Eurasia and the Yuan Empire, to address the questions of influence, contact, and exchange. In reframing the development of early European art as a fundamentally cross-cultural phenomenon, this project aims to offer a better understanding of the roots of our own global visual culture. ....Eurasian exchange and artistic transformation in art. This project aims to bring European and Chinese art history into dialogue. It explores the early Italian Renaissance in the larger geopolitical context of Mongol Eurasia and the Yuan Empire, to address the questions of influence, contact, and exchange. In reframing the development of early European art as a fundamentally cross-cultural phenomenon, this project aims to offer a better understanding of the roots of our own global visual culture. The project will benefit and enrich the study of cross-cultural contact and exchange in art history as a larger field, leading to the re-examination of art in the Australasian region.Read moreRead less
Outsider artists and the reformulation of Australian art. This project aims to produce an understanding of outsider artists, their lives, their histories, and the socio-historic context in which they made their work. “Outsider artists” includes artists experiencing incarceration, disability, mental illness and other forms of marginalisation. Integration of their work will lead to a deeper understanding of mainstream art in Australia to paint a richer, more complex picture of the history of Aust ....Outsider artists and the reformulation of Australian art. This project aims to produce an understanding of outsider artists, their lives, their histories, and the socio-historic context in which they made their work. “Outsider artists” includes artists experiencing incarceration, disability, mental illness and other forms of marginalisation. Integration of their work will lead to a deeper understanding of mainstream art in Australia to paint a richer, more complex picture of the history of Australian art. The project will alter the perspective of arts policy and agencies, and of Australian artists themselves.Read moreRead less
A new theory of Aboriginal art. The paradigms developed by scholars have a huge impact on the value of art. After the Australian artworld repositioned Aboriginal art from the frame of 'primitive art' to that of contemporary art, the price of and market for Aboriginal art increased enormously. However, Aboriginal art failed to penetrate the international contemporary artworld because the paradigms of contemporary art within which it was framed were outmoded. Through examining the production of Ab ....A new theory of Aboriginal art. The paradigms developed by scholars have a huge impact on the value of art. After the Australian artworld repositioned Aboriginal art from the frame of 'primitive art' to that of contemporary art, the price of and market for Aboriginal art increased enormously. However, Aboriginal art failed to penetrate the international contemporary artworld because the paradigms of contemporary art within which it was framed were outmoded. Through examining the production of Aboriginal art from the perspectives of its producers and recent globalised contemporary art practices, this project aims to develop a new theory of Aboriginal art that is more aligned with the thinking of current curators who set the agenda at the upper end of the market.Read moreRead less
Light, place and presence in the history of Australian photography. Photography is central to Australian history and national identity. It is a powerful tool through which our identities are forged, and through photography our understanding of our place in relation to our environments, each other and the world are made visible. By grounding this research in the unique status of light as a physical agent in photography and a key symbol of identity and place in Australia, this project will develop ....Light, place and presence in the history of Australian photography. Photography is central to Australian history and national identity. It is a powerful tool through which our identities are forged, and through photography our understanding of our place in relation to our environments, each other and the world are made visible. By grounding this research in the unique status of light as a physical agent in photography and a key symbol of identity and place in Australia, this project will develop a new approach to photography that enriches our social and cultural imagination, and propels Australian scholarship onto the international agenda. Read moreRead less
Curating Photography in the Age of Photo Sharing. This project aims to develop new curatorial models to enable Australian art galleries to respond effectively to changes in the medium of photography wrought by digital technologies. By conducting the first comprehensive analysis of nearly five decades of Australian photography curating and comparing it to curatorial approaches in related institutions locally and internationally, the project seeks to: identify the crucial role of photography exhib ....Curating Photography in the Age of Photo Sharing. This project aims to develop new curatorial models to enable Australian art galleries to respond effectively to changes in the medium of photography wrought by digital technologies. By conducting the first comprehensive analysis of nearly five decades of Australian photography curating and comparing it to curatorial approaches in related institutions locally and internationally, the project seeks to: identify the crucial role of photography exhibitions in the shaping of Australian visual culture; and develop opportunities for curators to better engage with the current proliferation of images, including new forms and practices of photography enabled by the Internet.Read moreRead less