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Could Pharmacological Restoration Of Mecp2 Levels Be Of Therapeutic Value In Rett Syndrome?
Funder
National Health and Medical Research Council
Summary
Rett syndrome is one of the commonest single gene cause of developmental disability in girls; 1:8500 Australian females are affected by the age of 12. There is currently no cure. Rett syndrome most commonly results from a fault in one copy of the Mecp2 gene on the X chromosome. The proposed research aims to identify medicines, already known to be safe in children and adults, which specifically improve the functioning of the Mecp2 gene. This should rapidly lead to targeted clinical treatments for ....Rett syndrome is one of the commonest single gene cause of developmental disability in girls; 1:8500 Australian females are affected by the age of 12. There is currently no cure. Rett syndrome most commonly results from a fault in one copy of the Mecp2 gene on the X chromosome. The proposed research aims to identify medicines, already known to be safe in children and adults, which specifically improve the functioning of the Mecp2 gene. This should rapidly lead to targeted clinical treatments for this condition.Read moreRead less
Investigation Of The Low Dose UV G2 Phase Checkpoint And Its Potential Exploitation In The Treatment Of Melanoma
Funder
National Health and Medical Research Council
Funding Amount
$35,085.00
Summary
The research aims to indentify the role UV exposure contributes to the development of melanoma and if this knowledge can be used to develop new methods in the prevention and treatment of this disease
Pulsed Laser Ablation Of Smear Layers In Root Canals
Funder
National Health and Medical Research Council
Funding Amount
$32,628.00
Summary
The project is in the general field of clinical dentistry, and in the speciality area of endodontics (root canal treatment). It examines the ability of several novel laser systems to remove bacteria and soft tissue debris from the root canals of teeth, building on recent developments in optical fiber technology and in antimicrobial therapy.