The Australian Research Data Commons (ARDC) invites you to participate in a short survey about your
interaction with the ARDC and use of our national research infrastructure and services. The survey will take
approximately 5 minutes and is anonymous. It’s open to anyone who uses our digital research infrastructure
services including Reasearch Link Australia.
We will use the information you provide to improve the national research infrastructure and services we
deliver and to report on user satisfaction to the Australian Government’s National Collaborative Research
Infrastructure Strategy (NCRIS) program.
Please take a few minutes to provide your input. The survey closes COB Friday 29 May 2026.
Complete the 5 min survey now by clicking on the link below.
CX3C chemokine signalling in the olfactory epithelium and its role in the self regeneration of the olfactory system. The current proposal will explore new venues in adult neural stem cell research and contribute to the further development of molecular biology and neuroscience research in Western Australia and Australia. The use of neural stem cells holds therapeutic promise for the treatment of a wide variety of neurological conditions, including neurotrauma and stroke. The proposed research wil ....CX3C chemokine signalling in the olfactory epithelium and its role in the self regeneration of the olfactory system. The current proposal will explore new venues in adult neural stem cell research and contribute to the further development of molecular biology and neuroscience research in Western Australia and Australia. The use of neural stem cells holds therapeutic promise for the treatment of a wide variety of neurological conditions, including neurotrauma and stroke. The proposed research will provide new data on the fundamental cellular and molecular events that are required to trigger the birth, differentiation and conditions for growth of new neurons in the adult nervous system. The generation of such insights will be critical for any translational research.
Read moreRead less
To investigate the role of the protein kinase SMG-1 in the stress response. This project is included in the designated priority area of research Promoting and Maintaining Good Health and Ageing Well. It represents a mouse model to assist in the study of human disease. It is the first mouse model for SMG-1, a protein kinase that protects against a variety of different forms of stress. The strength of the model is that it can be combined with other mouse models to interrogate and elucidate the eve ....To investigate the role of the protein kinase SMG-1 in the stress response. This project is included in the designated priority area of research Promoting and Maintaining Good Health and Ageing Well. It represents a mouse model to assist in the study of human disease. It is the first mouse model for SMG-1, a protein kinase that protects against a variety of different forms of stress. The strength of the model is that it can be combined with other mouse models to interrogate and elucidate the events occurring in different pathways for stress. The expectation is that ground-breaking data will be generated with this model providing scientific leadership on the role of this protein. It will also assist in establishing new collaborations.Read moreRead less
Assessing gene function in the developing brain using zebrafish as a model system. As the average life expectancy in western countries rises there is an increasing incidence of mental health problems. Therapeutic approaches to both Alzhemier's and Parkinson's disease, as well as to brain injury following stroke, rely on a thorough understanding of how the brain develops. This is consistent with the everyday principle that if you want to fix something that is broken, then you need to understand h ....Assessing gene function in the developing brain using zebrafish as a model system. As the average life expectancy in western countries rises there is an increasing incidence of mental health problems. Therapeutic approaches to both Alzhemier's and Parkinson's disease, as well as to brain injury following stroke, rely on a thorough understanding of how the brain develops. This is consistent with the everyday principle that if you want to fix something that is broken, then you need to understand how it is put together in the first place. This project seeks to understand how the normal brain is wired together in the embryo and, in doing so it will expose novel targets for therapy in the aged.Read moreRead less
Understanding the molecular basis of marine invertebrate larval settlement and metamorphosis using complementary molecular, developmental, chemical and ecological approaches. The colonisation and fouling of submerged structures is a major economic problem for maritime industries. This proposal will detail the molecular mechanisms underlying the first crucial steps of marine invertebrate colonisation - settlement and metamorphosis - and determine how natural anti-foulant chemicals impact on these ....Understanding the molecular basis of marine invertebrate larval settlement and metamorphosis using complementary molecular, developmental, chemical and ecological approaches. The colonisation and fouling of submerged structures is a major economic problem for maritime industries. This proposal will detail the molecular mechanisms underlying the first crucial steps of marine invertebrate colonisation - settlement and metamorphosis - and determine how natural anti-foulant chemicals impact on these developmental processes. By using complementary developmental, molecular, chemical and ecological approaches, we will obtain knowledge of key control points in settlement and metamorphosis, and thus identify potential pest management strategies. This proposal comprehensively delineates the role of novel anti-foulants, linking their effect on invertebrate development with their role in shaping marine communities on natural and built surfaces.Read moreRead less
Cross-kingdom communications via small non-coding RNAs. This project aims to determine the role of small non-coding RNAs in mosquito-Wolbachia interactions, including Wolbachia microRNAs, concentrating on exchanged microRNAs between the two organisms and explore microRNAs effect on Wolbachia maintenance and its anti-viral property. Small non-coding RNAs play significant roles in various biological processes, including host-microorganism interactions. Recent evidence suggests that small RNAs can ....Cross-kingdom communications via small non-coding RNAs. This project aims to determine the role of small non-coding RNAs in mosquito-Wolbachia interactions, including Wolbachia microRNAs, concentrating on exchanged microRNAs between the two organisms and explore microRNAs effect on Wolbachia maintenance and its anti-viral property. Small non-coding RNAs play significant roles in various biological processes, including host-microorganism interactions. Recent evidence suggests that small RNAs can be exchanged between microorganisms and their hosts and regulate gene expression in the other organism. The endosymbiotic bacterium, Wolbachia, has attracted worldwide attention due to inhibiting replication of various vector-borne pathogens in mosquito vectors.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE130101089
Funder
Australian Research Council
Funding Amount
$371,800.00
Summary
Understanding masculinity, the crustacean way. The androgenic gland is responsible for maleness in crustaceans. This project will characterise the genes that control the masculinisation process in crustaceans, discovering new targets for sex reversal and sterility induction. These findings will have implications for aquaculture and the development of innovative tools for invasive/pest crustacean control.