Towards the sustainable discovery and development of new antibiotics. This project aims to define how to access silent biosynthetic genes within microbial genome to facilitate access to new chemical diversity hidden within microbial genomes. Using interdisciplinary approaches in genome mining and metabolomics technologies, the project expects to inspire and enable the future design of more effective antibiotics. Expected outcomes from this program include define new microbial defence molecules, ....Towards the sustainable discovery and development of new antibiotics. This project aims to define how to access silent biosynthetic genes within microbial genome to facilitate access to new chemical diversity hidden within microbial genomes. Using interdisciplinary approaches in genome mining and metabolomics technologies, the project expects to inspire and enable the future design of more effective antibiotics. Expected outcomes from this program include define new microbial defence molecules, to meet future demands in agrochemical and environmental sciences. It will also train future scientists and develop international collaborations. This should provide significant benefit, including a higher-quality workforce for research and innovation, positioning Australia at the forefront of drug discovery. Read moreRead less