Combating The Global Medical Challenge Caused By Gram-negative 'superbugs': From Redeveloping The Polymyxins To Discovering Novel Antibiotics
Funder
National Health and Medical Research Council
Funding Amount
$375,012.00
Summary
Bacterial �superbugs� are becoming a major global medical challenge. Polymyxins are the last-line antibiotics against Gram-negative �superbugs� but with little pharmacological information available. I am an antimicrobial pharmacologist specialised in re-developing polymyxins, and discovering novel antibiotics against these very troublesome bacteria. My research targets the _Bad Bugs, No Drugs� disaster highlighted by the Infectious Diseases Society of America and the World Health Organization.
Prof Paterson is an Infectious Diseases Physician studying the molecular and clinical epidemiology of infections with Gram negative bacteria producing newer beta-lactamases.
Discovery And Exploitation Of Novel Biophysical Methods For Charcterising Molecular Pathways Invld In Disease Progression
Funder
National Health and Medical Research Council
Funding Amount
$4,000,000.00
Summary
Dr Cooper has conducted groundbreaking research into the progression and spread of antibiotic-resistant bacterial pathogens. Utilising a strongly multidisciplinary approach, he will use his Fellowship to expand upon this research in the area of antibiotic resistance and will supplement this focus with research into biofilms formed by bacterial pathogens on medical implants, cannulas and catheters. Dr Cooper’s Australia Fellowship will also assist his research into the changes that occur in cells ....Dr Cooper has conducted groundbreaking research into the progression and spread of antibiotic-resistant bacterial pathogens. Utilising a strongly multidisciplinary approach, he will use his Fellowship to expand upon this research in the area of antibiotic resistance and will supplement this focus with research into biofilms formed by bacterial pathogens on medical implants, cannulas and catheters. Dr Cooper’s Australia Fellowship will also assist his research into the changes that occur in cells during the initiation and evolution of cancer.Read moreRead less
I am an immunologist studying the interaction between cancer and the immune system. I am involved in the development and characterization of immunotherapies for cancer.
I am an applied physiologist determining risk factors for falls and strategies for prevention in older people and clinical groups with balance disorders. I pursue this research primarily through epidemiological studies.
I am a cardiovascular clinician-scientist involved in characterising the cellular and molecular pathogenesis of heart failure. My goal is to translate these findings into clinical solutions.