Pathophysiology And Alternative Preventative Strategy For Breast Cancer Chemotherapy-induced Bone Loss
Funder
National Health and Medical Research Council
Funding Amount
$540,356.00
Summary
Combination cytotoxic chemotherapy is the current optimal approach for treating breast cancer in premenopausal women. However, long-term skeletal defects (osteoporosis and fractures) caused by the chemotherapy have become an increasingly serious problem due to its intensified use and improved patient survival rate. This project seeks to elucidate the mechanisms for chemotherapy-induced bone defects and to initiate development of a preventative treatment using natural bioactive micronutrients.
Combined Dry-needling, Advice And Graded Exercise: A Randomized Controlled Trial In Chronic Whiplash
Funder
National Health and Medical Research Council
Funding Amount
$309,339.00
Summary
Central hyperexcitability is a feature of chronic whiplash and may be one reason for the poor response of this condition to standard treatment approaches such as exercise. Complementary and Alternative Medicine (CAM) treatment of dry-needling has shown potential to decrease this hypersensitivity in other musculoskeletal conditions. This study will investigate the effects of dry-needling combined with an orthodox treatment of advice and graded exercise on pain and disability in chronic whiplash.
The Ecstasy Check-Up: A Multi-site Trial Of A Brief Intervention For Ecstasy Use Among Regular Ecstasy Users
Funder
National Health and Medical Research Council
Funding Amount
$458,432.00
Summary
Rates of ecstasy use have continued to rise rapidly over the past 10-15 years, particularly among young people. This is of concern, as several studies indicate that ecstasy is associated with a range of short- and long-term harms. Although many users acknowledge risks associated with ecstasy use, few users seek treatment. Therefore, the current project will aim to reduce ecstasy use and harm by providing non-treatment seeking ecstasy users with a brief motivational intervention.
The Efficacy And Safety Of Acupuncture For Seasonal Allergic Rhinitis: A Prospective, Randomised Controlled Trial
Funder
National Health and Medical Research Council
Funding Amount
$175,732.00
Summary
Seasonal allergic rhinitis, also known as hay fever, is a common condition with high prevalence in Australia, being most pronounced during spring and early summer when pollen counts are highest. There is no proven cure for hay fever. Many hay fever sufferers seek alternative therapies such as acupuncture. We propose to undertake a rigorous study, using well-established clinical trial methodology, to evaluate the efficacy and safety of acupuncture in the treatment of hay fever.
The Feasibility And Effectiveness Of A Family-based Intervention For Indigenous Australians With Alcohol Dependence.
Funder
National Health and Medical Research Council
Funding Amount
$218,291.00
Summary
This study aims to determine the feasibility of implementing a family-based intervention in an Indigenous community-controlled health service in rural NSW and it's level of acceptability to Indigenous patients. The expected main benefits of implementing the family-based intervention are increases in the percentage of Indigenous individuals with alcohol dependence entering and engaging in evidence-based treatment.
A Randomised Trial Assessing A Shade Development Intervention In Secondary Schools For Adolescent Skin Cancer Prevention
Funder
National Health and Medical Research Council
Funding Amount
$709,615.00
Summary
Skin cancer is a significant burden to health costs, and morbidity and mortality in Australia. Reduction of exposure to ultraviolet radiation (UVR) in sunlight, particularly during childhood and adolescence is an important strategy for preventing skin cancer in later life. Adolescents have been particularly resistant to skin cancer prevention messages. Despite a high knowledge of skin cancer, the majority of Australian adolescents report a reliance on sunscreen, a resistance to hat wearing, and ....Skin cancer is a significant burden to health costs, and morbidity and mortality in Australia. Reduction of exposure to ultraviolet radiation (UVR) in sunlight, particularly during childhood and adolescence is an important strategy for preventing skin cancer in later life. Adolescents have been particularly resistant to skin cancer prevention messages. Despite a high knowledge of skin cancer, the majority of Australian adolescents report a reliance on sunscreen, a resistance to hat wearing, and commonly experience sunburn, an important indicator of increased risk of skin cancer. Psycho-social interventions have shown limited influence on adolescents' sun protective behaviours to date. The current research proposal explores an alternative approach to psycho-social interventions for adolescents. The study will assess the effect of increasing available shade at secondary schools. In a randomised control trial study design, the change in the number of students using certain outdoor areas at intervention schools will be observed 'before' and 'after' the installation of built shade sail structures. Our main hypothesis states that the number of students using these newly shaded areas in intervention schools will increase compared with use of equivalent unshaded areas in control schools. Shade development is increasingly becoming an issue for secondary schools and given both the high cost of providing shade structures and adolescents' resistance to other forms of sun protection it is important to establish that adolescents will use this form of sun protection. This study will determine whether adolescents actively avoid or seek shade and so provide evidence for informing decisions about further investment in shade provision in schools.Read moreRead less
Calling The Tune? Investigating Corporate Influences On Media Reporting Of Health
Funder
National Health and Medical Research Council
Funding Amount
$462,016.00
Summary
This project will examine and evaluate the relationships between Australian journalists and health-related industries (pharmaceutical, medical devices-diagnostics, complementary medicines, food and alcohol) in order to determine the extent to which, and ways in which, these relationships influence the health-related information received by health professionals and the Australian public. The project aims to inform strategies to improve industry and journalistic policy and practices.
Evaluation Of An Instrument For Management Of Behavioural And Psychological Symptoms Of Dementia.
Funder
National Health and Medical Research Council
Funding Amount
$598,468.00
Summary
Behavioural and Psychological Symptoms of Dementia (BPSD) distress the patient and others. The behaviours, and not the underlying causes, are often treated with antipsychotics, despite side effects and low efficacy. An assessment instrument for care staff to determine and address causes of BPSD will be implemented. We predict training will reduce inappropriate prescribing and other reasons for distress. Where medication is required, detailed information will assist more targeted prescribing.