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Spatial analysis of a linked environmental, health and social data base. Extensive environmental, health and socio-demographic data are routinely collected by various agencies throughout Australia. To date, it has been difficult to link separate databases and investigate possible associations between the different parameters within them. In this proposal we plan to link routinely collected health, environment and socio-demographic data from a number of databases. We then plan to develop tools fo ....Spatial analysis of a linked environmental, health and social data base. Extensive environmental, health and socio-demographic data are routinely collected by various agencies throughout Australia. To date, it has been difficult to link separate databases and investigate possible associations between the different parameters within them. In this proposal we plan to link routinely collected health, environment and socio-demographic data from a number of databases. We then plan to develop tools for geo-referencing the data. Finally we plan to perform spatial analysis of the linked data, specifically investigating associations between environmental and social factors and childhood leukaemia, deliberate self harm and adverse birth outcomes. Linking separate databases and performing spatial analysis of georeferenced data will substantially improve the quality of public health surveillance and research in NSW. In addition, it will enable more detailed analysis of the effects of environmental exposures on health, using routine data.Read moreRead less
Environmental quality and health in the elderly; The Australian situation and international comparison. The elderly are a vulnerable population group that should receive particular attention in health policy. They are a group of considerable and growing size that contributes disproportionately to total health burden. Although residential environment is likely to influence health and well-being among the elderly, the evidence-base for appropriate policy and practice is lacking. Improved understa ....Environmental quality and health in the elderly; The Australian situation and international comparison. The elderly are a vulnerable population group that should receive particular attention in health policy. They are a group of considerable and growing size that contributes disproportionately to total health burden. Although residential environment is likely to influence health and well-being among the elderly, the evidence-base for appropriate policy and practice is lacking. Improved understanding of the role of relevant environmental factors could lead to substantially reduced morbidity and mortality (and associated costs) for the key outcomes: falls, and cardiovascular and respiratory disease. Results will contribute to the international evidence-base in this increasingly critical area of research, policy, and practice. Read moreRead less
Metal emissions from petrol and the future health of children. We aim to determine the contribution of manganese, lead, and other metal emissions from motor vehicles to the environment and exposure of
children. Manganese is of potential concern because of (a) its recent
introduction as methylcyclopentadienyl manganese tricarbonyl (MMT) in
Australia as a fuel additive to replace lead and (b) the lack of information on environmental levels, exposure, and long-term health effects, especially in ....Metal emissions from petrol and the future health of children. We aim to determine the contribution of manganese, lead, and other metal emissions from motor vehicles to the environment and exposure of
children. Manganese is of potential concern because of (a) its recent
introduction as methylcyclopentadienyl manganese tricarbonyl (MMT) in
Australia as a fuel additive to replace lead and (b) the lack of information on environmental levels, exposure, and long-term health effects, especially in children. This project conforms with a Designated National Research Priority and is a collaborative project bringing together researchers from academia, CSIRO, industry, and the US.
Environmental Protection Agency.
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Novel compounds as natural herbicides for weed management. The development by weeds of herbicide resistance has undermined these systems and limited prospect for development of new chemicals with different modes of actions through traditional methods. Such methods of searching for new herbicides are yielding diminishing returns and the associated costs are becoming prohibitive.
This project aims to develop herbicides by evaluating, isolating and identifying novel natural compounds present in a ....Novel compounds as natural herbicides for weed management. The development by weeds of herbicide resistance has undermined these systems and limited prospect for development of new chemicals with different modes of actions through traditional methods. Such methods of searching for new herbicides are yielding diminishing returns and the associated costs are becoming prohibitive.
This project aims to develop herbicides by evaluating, isolating and identifying novel natural compounds present in a range of weeds and crop plants.
The outcomes will be reduced herbicide inputs, and the development of a new group of natural herbicides to counteract the threat imposed by the development of herbicide resistance.
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Novel compounds as natural herbicides for weed management. The development by weeds of herbicide resistance has undermined minimum-tillage systems and heightened the limited prospects for development of new chemicals with different modes of actions through traditional methods. Such methods of searching for new herbicides are yielding diminishing returns and the associated costs are becoming prohibitive.
This project aims to develop herbicides by evaluating, isolating and identifying novel nat ....Novel compounds as natural herbicides for weed management. The development by weeds of herbicide resistance has undermined minimum-tillage systems and heightened the limited prospects for development of new chemicals with different modes of actions through traditional methods. Such methods of searching for new herbicides are yielding diminishing returns and the associated costs are becoming prohibitive.
This project aims to develop herbicides by evaluating, isolating and identifying novel natural compounds present in a range of weeds and crop plants.
The outcomes will be reduced herbicide inputs, and the development of a new group of natural herbicides to counteract the threat imposed by the development of herbicide resistance.Read moreRead less
Combining Community Based Social Marketing and Technological Innovation to Combat Wood-Smoke Pollution in Regional Australia. There is considerable evidence to suggest that wood smoke pollution represents a serious health threat. This project will provide valuable information about the relative effectiveness of social marketing and technology-based interventions to reduce wood smoke pollution, and how these interventions may be combined to maximise their impact. The resulting improvements in ai ....Combining Community Based Social Marketing and Technological Innovation to Combat Wood-Smoke Pollution in Regional Australia. There is considerable evidence to suggest that wood smoke pollution represents a serious health threat. This project will provide valuable information about the relative effectiveness of social marketing and technology-based interventions to reduce wood smoke pollution, and how these interventions may be combined to maximise their impact. The resulting improvements in air quality may produce substantial health benefits for the residents of Australian communities that depend heavily on wood as a domestic heating fuel during winter months. Read moreRead less
Quantifying the effects of criteria air pollutants on child health - setting Australian air quality standards. The project is proposed and supported by the National Environment and Heritage Protection Council, who will be reviewing Australian air quality standards from 2005. The study aims to determine whether current air quality standards adequately protect the health of Australian school children, and to provide nationally-based information to inform any changes to the current standards. A cr ....Quantifying the effects of criteria air pollutants on child health - setting Australian air quality standards. The project is proposed and supported by the National Environment and Heritage Protection Council, who will be reviewing Australian air quality standards from 2005. The study aims to determine whether current air quality standards adequately protect the health of Australian school children, and to provide nationally-based information to inform any changes to the current standards. A cross-sectional study will examine cumulative effects; a nested panel study will quantify day-to-day effects of air pollution in sensitive children. Sampling will ensure national representation and generalisability of findings. This will be the first nationally-based study of the relationship between air quality and child health in Australia.Read moreRead less
Generalised Linear Mixed Models: Theory, Methods and New Areas of Application. This project will aid the analysis of complex data sets throughout Australia. The ensuing methodology and software products will be applicable to data arising from longitudinal and geo-referenced public health and biomedical studies being conducted in Australia. It will also aid analysis of complex survey data from the Australian Bureau of Statistics and other agencies. Part of this project is geared towards smart inf ....Generalised Linear Mixed Models: Theory, Methods and New Areas of Application. This project will aid the analysis of complex data sets throughout Australia. The ensuing methodology and software products will be applicable to data arising from longitudinal and geo-referenced public health and biomedical studies being conducted in Australia. It will also aid analysis of complex survey data from the Australian Bureau of Statistics and other agencies. Part of this project is geared towards smart information use in Australian industries and will help foster collaboration between mathematical scientists and members of the Australian business sector. Cancer research in Australia will also benefit from this project.Read moreRead less
The development of a two-colour flow cytometric assay for the detection of whole cell biosensors in environmental samples. Macquarie University and the University of Copenhagen have expertise in fluorescence detection and whole cell biosensors respectively. The project will take advantage of these skills and develop a sensitive assay for monitoring biosensor bacteria in soil. The technology will be significant as it will enable real time analysis of antibiotic production in situ through the de ....The development of a two-colour flow cytometric assay for the detection of whole cell biosensors in environmental samples. Macquarie University and the University of Copenhagen have expertise in fluorescence detection and whole cell biosensors respectively. The project will take advantage of these skills and develop a sensitive assay for monitoring biosensor bacteria in soil. The technology will be significant as it will enable real time analysis of antibiotic production in situ through the detection of GFP expression. This work will then be used to isolate new antibiotic produces and will be extended to research into the bioavailability of toxic compounds and stress. An existing collaboration between the two institutions will be extended enabling the transfer and application of biosensor technology to Australia.Read moreRead less
Understanding the health effects of landscape burning and biomass smoke in Australian towns and cities. Bushfires are increasingly affecting Australian towns and cities directly and indirectly from episodes of severe air pollution. An approach to manage bushfires is to reduce fuel loads by setting planned fires under stable weather conditions, yet this strategy is controversial because of community concerns about ecological sustainability and negative health impacts from smoke. The relative im ....Understanding the health effects of landscape burning and biomass smoke in Australian towns and cities. Bushfires are increasingly affecting Australian towns and cities directly and indirectly from episodes of severe air pollution. An approach to manage bushfires is to reduce fuel loads by setting planned fires under stable weather conditions, yet this strategy is controversial because of community concerns about ecological sustainability and negative health impacts from smoke. The relative importance of air pollution from planned and unplanned bushfires vs. wood heaters, agricultural burning and other sources of air pollution will be determined. Our study will enable evidence-based bushfire smoke management, help formulate national air quality standards and shape policies regarding biomass smoke and bushfire management.Read moreRead less