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Clinical And Physiological Features Of Obstructive Sleep Apnoea Phenotypes
Funder
National Health and Medical Research Council
Funding Amount
$117,331.00
Summary
Obstructive sleep apnoea has variable causes and clinical effects in different patient groups. My research will quantify the contribution of various physiological processes to the development of upper airway obstruction in different sub-types of sleep apnoea and to determine how this affects clinical presentation. I will be measuring a number of physiological parameters, and finding out how sleep apnoea manifests in terms of symptomatology and adverse health effects.
Evaluation Of A Healthy Lifestyle Intervention Targeting Young People Living In Out-of-home Care
Funder
National Health and Medical Research Council
Funding Amount
$69,099.00
Summary
Recent National findings reveal that on average, 45% of Australian children aged 5-14 years watch TV for at least 2 hours/day. Given the risk for adverse cognitive, behavioral and physical health outcomes related to excessive TV viewing, including childhood obesity, there is an urgent need to design effective interventions to reduce unhealthy TV habits in the early years. My project responds to this need.
Improving Outcomes For Children With Emotional And Behavioural Difficulties Through A School-based Intervention: A Pilot Randomised Controlled Trial.
Funder
National Health and Medical Research Council
Funding Amount
$88,662.00
Summary
Over 50% of adult mental illness begins during childhood. Our health system is under increasing strain to support such children, especially public services. Teachers are in an ideal position to detect emerging issues and organise intervention, but they need help. This project aims to explore the potential for a collaboration between health and education to identify children with emotional and behavioural difficulties sooner and more accurately, and put in place effective strategies of support.
Chronic obstructive pulmonary disease (COPD) causes airway narrowing and lung destruction resulting in breathlessness and cough. Earlier detection of acute attacks of breathlessness may improve treatment, prevent progression and reduce risk of death. The forced oscillation technique can detect attacks earlier and is easy to perform. It will be used in this study for home monitoring with application of time series analyses to accurately detect change so that acute attacks can be treated earlier.
Application Of 3D Morphometrics To The Assessment Of Typical And Disordered Craniofacial Growth
Funder
National Health and Medical Research Council
Funding Amount
$48,065.00
Summary
Traditionally, assessing the growth of the head and face has relied on measuring changes in distances and angles between landmarks on either patients, photographs or x-rays. This is not only slow but also not very accurate. This project will automate the identification of these landmarks on 3D images and quantify normal growth of the head and face. From this we can develop methods of quantifying abnormal growth and use these to understand the impact of surgical interventions on children.
THE EFFECT OF LONG ACTING BRONCHODILATORS ON VENTILATION IN COPD
Funder
National Health and Medical Research Council
Funding Amount
$143,676.00
Summary
COPD is a common and important smoking-related lung disease. Well-established treatments with inhaled medications including long-acting bronchodilators have a proven clinical track record. However the physiological basis for their effects is still under investigation. This research examines some of the physiological changes in lung function and the response to long-acting bronchodilators in patients with COPD, and may help explain why some patients respond to therapy while others do not, leading ....COPD is a common and important smoking-related lung disease. Well-established treatments with inhaled medications including long-acting bronchodilators have a proven clinical track record. However the physiological basis for their effects is still under investigation. This research examines some of the physiological changes in lung function and the response to long-acting bronchodilators in patients with COPD, and may help explain why some patients respond to therapy while others do not, leading to more targeted therapeuticsRead moreRead less
A Prospective Multicentre Randomized Study To Evaluate The Impact Of OSA Treatment With CPAP On Atrial Electrical And Structural Substrate And On Long Term Maintenance Of Sinus Rhythm Following Catheter Ablation Of Atrial Fibrillation
Funder
National Health and Medical Research Council
Funding Amount
$128,224.00
Summary
Atrial fibrillation(AF) is the commonest heart rhythm disorder causing stroke, heart failure and increased mortality. Similarly, obstructive sleep apnea(OSA) is increasingly recognised as a modern epidemic. Epidemiological data have demonstrated an independent association between the two conditions. We will conduct a prospective multicenter randomized study to evaluate the impact of OSA treatment on: (i)maintenance of sinus rhythm after catheter ablation of AF, (ii)atrial structure and function
The Impact Of Infant Feeding Practices And In Utero Exposure To Bisphenol A On Respiratory Health And Somatic Growth In Early Childhood
Funder
National Health and Medical Research Council
Funding Amount
$120,253.00
Summary
Bisphenol A is a chemical often used in making plastic containers, including infant bottles. It is known to leach from plastic into food in very low doses. Exposure to high levels of bisphenol A is believed to trigger chemical pathways in the body which increase the risk of obesity and asthma. This project will follow a group of pregnant women and infants to observe the level of exposure to bisphenol A in Australia, and to investigate how exposure to bisphenol A correlates to asthmatic symptoms, ....Bisphenol A is a chemical often used in making plastic containers, including infant bottles. It is known to leach from plastic into food in very low doses. Exposure to high levels of bisphenol A is believed to trigger chemical pathways in the body which increase the risk of obesity and asthma. This project will follow a group of pregnant women and infants to observe the level of exposure to bisphenol A in Australia, and to investigate how exposure to bisphenol A correlates to asthmatic symptoms, growth and fat deposition in early childhood.Read moreRead less
So Like Your Mum! Is The Health Of Mothers In Far North Queensland Reflected In The Nutrition And Growth Of Their Children In Early Life?
Funder
National Health and Medical Research Council
Funding Amount
$96,631.00
Summary
The health, nutrition and growth of a baby reflect the health and nutrition status of its mother. We will link routine health service information for Indigenous mothers with information on the growth, haemoglobin and health of their young children to identify key factors in a mother’s pregnancy and before, influencing the future health and development of their babies. This study will shape interventions to improve the health of mothers, and thus improve the health of their children through life.