Risk Factors For Asthma, Chronic Bronchitis And Emphysema In Older Adults
Funder
National Health and Medical Research Council
Funding Amount
$330,574.00
Summary
Chronic obstructive pulmonary disease (including chronic bronchitis and emphysema) is a major public health problem in Australia. The main known cause is cigarette smoking, which peaked among Australian men shortly after the second world war. Now that the consequences of this epidemic of smoking are passing, more attention needs to be paid to other causes of the condition. The proposed study will focus on occupational and domestic exposures and dietary factors in older people. Dusty jobs have lo ....Chronic obstructive pulmonary disease (including chronic bronchitis and emphysema) is a major public health problem in Australia. The main known cause is cigarette smoking, which peaked among Australian men shortly after the second world war. Now that the consequences of this epidemic of smoking are passing, more attention needs to be paid to other causes of the condition. The proposed study will focus on occupational and domestic exposures and dietary factors in older people. Dusty jobs have long been associated with COPD. However it is not known to what extent other occupational exposures to fumes and vapours are also responsible. Identifying such jobs would lead to better workplace conditions and prevention of further cases. Workers who have already developed COPD could be more fairly compensated. Similarly if indoor exposures to tobacco smoke and unvented gas appliances were found to play a role, further controls on smoking, flues and improved ventilation could also prevent cases of COPD. It is generally thought that emphysema develops from an imbalance between the oxidative stresses on the lungs and protective enzymes. A diet high in antioxidant vitamins and fish may protect against the development of COPD. If confirmed by this study, it would then be possible to conduct clinical trials of supplementation in smokers at risk of developing COPD. Public nutritional education could reduce the incidence of the condition in the future.Read moreRead less
Impact Of Exposure To Air Pollutants During The Prenatal Period On Lung Function In Infancy
Funder
National Health and Medical Research Council
Funding Amount
$635,093.00
Summary
The lungs undergo rapid development both before birth and in the early years of life and therefore may be susceptible to the impacts of exposure to environmental pollutants. Poor lung function in early childhood may increase the risk for respiratory disease in later life. This study will investigate if exposure to air pollution, indoors and outdoors, before birth significantly affects lung function and the respiratory health of young children.
A Randomised Controlled Trial Investigating The Respiratory Effects Of Nitrogen Dioxide In Schoolchildren
Funder
National Health and Medical Research Council
Funding Amount
$212,189.00
Summary
Research has shown that exposures to air pollutants such as nitrogen dioxide (NO2), sulphur dioxide, ozone and respirable particulate matter less than 10 microns are associated with respiratory symptoms. Unlike the other air pollutants nitrogen dioxide is an indoor gas which occurs in higher concentrations than outdoors in households which cook or heat with gas. Recent research has demonstrated that NO2 at concentrations easily achieved indoors can increase respiratory illness, particularly in c ....Research has shown that exposures to air pollutants such as nitrogen dioxide (NO2), sulphur dioxide, ozone and respirable particulate matter less than 10 microns are associated with respiratory symptoms. Unlike the other air pollutants nitrogen dioxide is an indoor gas which occurs in higher concentrations than outdoors in households which cook or heat with gas. Recent research has demonstrated that NO2 at concentrations easily achieved indoors can increase respiratory illness, particularly in children and asthmatics. In South Australia we have the opportunity to demonstrate health effects of NO2 on children with asthma more conclusively, as a high number of schools heat their classrooms with unflued gas heaters which produce high NO2. In the proposed study, half of the primary schools with unflued gas heaters will have these heaters replaced with heaters which do not emit NO2. This process of selecting schools will be performed at random and in the school holidays, so as not to bias the children in regard to their exposure status. Additionally, only asthmatic children without gas appliances at home will be included. Asthma symptoms and lung function measurements will be collected in order to determine any differences in the health outcomes of both groups. The results of this study will be able to give conclusive information on health effects related to NO2, that will substantially contribute to the development of a recommended NO2 guideline. This is of worldwide interest.Read moreRead less
Reducing Indoor Air Pollution In The Home: A Randomised Controlled Trial Of A Behavioural Intervention.
Funder
National Health and Medical Research Council
Funding Amount
$85,552.00
Summary
Exposure to air pollution is not confined to pollution emitted outdoors by motor vehicles and industry. We are exposed to a diverse and complex mix of indoor pollutants produced in many cases by everyday activities. Since we spend about 70-90% of our time indoors, the potential effect of these pollutants on our health is important and of concern. There is a growing number of scientific studies that confirm the importance of indoor air pollution to our health. Two indoor pollutants commonly found ....Exposure to air pollution is not confined to pollution emitted outdoors by motor vehicles and industry. We are exposed to a diverse and complex mix of indoor pollutants produced in many cases by everyday activities. Since we spend about 70-90% of our time indoors, the potential effect of these pollutants on our health is important and of concern. There is a growing number of scientific studies that confirm the importance of indoor air pollution to our health. Two indoor pollutants commonly found in the home are nitrogen dioxide (NO2) emitted from gas appliances and environmental tobacco smoke (ETS). ETS, or passive smoking, is known to increase lower respiratory tract illness in children, asthma, lung cancer and cardiovascular disease. Studies have shown that NO2 may increase respiratory symptoms and exacerbate the response of asthmatics to allergens such as house dust mites. In this project we extend our earlier work on indoor air pollution, with the aim of evaluating simple and effective ways to improve air quality in the home. Parents of school children from the Newcastle area will be invited to participate in the study. Parents will receive information about the health risks of indoor air pollution and advice on how to decrease the levels in their home. We will monitor the air quality in each participant's home to see whether the education program has helped parents to decrease the levels of NO2 and ETS in their home. We will also examine whether a reduction in these pollutants has improved the lung health of the children in the study.Read moreRead less