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Country : Australia
Research Topic : ageing caregivers
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  • Funded Activity

    The Role Of Central Haemodynamics In Type 2 Diabetes Mellitus-related Brain Disease

    Funder
    National Health and Medical Research Council
    Funding Amount
    $899,704.00
    Summary
    Type 2 Diabetes Mellitus is associated with stiffening of major blood vessels which may allow the transmission of harmful pressure to the small vessels of the brain. This may in turn be responsible for damage to brain cells and a greater risk of dementia. This study will use state-of-the art techniques to test this theory. If true, it may open opportunities to reduce the risk of brain disease in diabetes by using therapies to reduce arterial stiffening.
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    Funded Activity

    Is Placental Aging The Key To Understanding, Predicting And Preventing Stillbirth?

    Funder
    National Health and Medical Research Council
    Funding Amount
    $473,861.00
    Summary
    Stillbirth occurs in 35 times as many pregnancies as sudden infant death but the causes are unknown. This project will help to develop tests that can predict the risk of stillbirth so that the obstetrician can deliver the baby before it dies. The investigators hypothesise that stillbirth is due to aging of the placenta and that markers of the aging placenta can be detected in the mother’s blood. The project brings together experts in the placenta, aging and obstetric care of high risk pregnancy.
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    Funded Activity

    Prevalence Of Dementia In The Torres Strait And Common Health Issues Of Later Life In The Torres Strait

    Funder
    National Health and Medical Research Council
    Funding Amount
    $365,000.00
    Summary
    The aim of the project is to assess the prevalence of dementia in people aged 45 years and over living in Torres Strait Islander communities and identify potential risk and protective factors associated with dementia risk. An additional aim is to revalidate a culturally appropriate cognitive assessment tool, the Kimberley Indigenous Cognitive Assessment (KICA) for use in the Torres Strait.
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    Funded Activity

    ASPREE Completion Project

    Funder
    National Health and Medical Research Council
    Funding Amount
    $4,796,725.00
    Summary
    ASPREE is the largest clinical trial ever conducted in Australia and will determine whether daily low dose aspirin prevents disease in healthy older people. The study was well-funded initially but will require additional support to complete the vital final stage of data collection and analysis. This will enable the study to answer important questions about the benefits and risks of aspirin in this age group and its effect on disability free survival.
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    Funded Activity

    CareTrack Aged: Appropriate Care Delivered To Australians Living In Residential Aged Care

    Funder
    National Health and Medical Research Council
    Funding Amount
    $1,157,722.00
    Summary
    Given Australia’s rapidly ageing population, keeping up with future demands and maintaining quality of care in residential aged care facilities (RACF) is vital. This study will assess whether care delivered is consistent with the evidence in 15 conditions that are frequently managed in RACFs. These will include delirium, dementia, depression, pain management and medication management. We will also assess the quality of life of residents in RACFs.
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    Funded Activity

    The Older Australian Twins Study (OATS) Of Healthy Brain Ageing And Age-related Neurocognitive Disorders

    Funder
    National Health and Medical Research Council
    Funding Amount
    $940,960.00
    Summary
    Ageing is associated with cognitive decline and dementia. It is still not completely understood what relative contributions genes and environment play in these. This project is an extension of the Older Australian Twins Study to examine genetic and environmental factors associated with late life brain changes and dementia, and will establish an internationally significant cohort for novel discovery.
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    Funded Activity

    Footwear For Self-managing Knee Osteoarthritis Symptoms: The Footstep Trial

    Funder
    National Health and Medical Research Council
    Funding Amount
    $590,532.00
    Summary
    Self-management of symptoms is an important part of treatment for people with knee osteoarthritis. Footwear influences forces across the knee joint and it is unclear which types of shoes are best to minimise arthritis symptoms. This study will compare the effects of flat flexible shoes to stable supportive shoe styles on pain and physical function over 6 months in people with painful knee osteoarthritis.
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    Funded Activity

    Low Dose Aspirin And Age-related Macular Degeneration: Randomised Controlled Trial

    Funder
    National Health and Medical Research Council
    Funding Amount
    $1,043,189.00
    Summary
    Age-related macular degeneration (AMD) is a major cause of visual impairment in advanced countries, responsible for nearly half of all legal blindness in Australia. Due to increased life expectancy, the number of people with this progressive late onset disease will double by 2025. Aspirin could prevent or delay the onset of AMD in older persons but its bleeding risk also needs to be considered. This project will determine whether treatment with low dose aspirin reduces incidence or progression o .... Age-related macular degeneration (AMD) is a major cause of visual impairment in advanced countries, responsible for nearly half of all legal blindness in Australia. Due to increased life expectancy, the number of people with this progressive late onset disease will double by 2025. Aspirin could prevent or delay the onset of AMD in older persons but its bleeding risk also needs to be considered. This project will determine whether treatment with low dose aspirin reduces incidence or progression of AMD.
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    Funded Activity

    Restoration Of Cognitive Deficits Induced By Diabetes Through The Modulation Of Cerebrovascular Integrity

    Funder
    National Health and Medical Research Council
    Funding Amount
    $261,251.00
    Summary
    Diabetes is a known risk factor for the development of dementia. However the details of this association have not been known. Recent evidence consistently shows that the integrity of blood vessels in the brain may be central to the onset of dementia, and consistently, damaged brain blood vessels are often reported in diabetic patients and animal models. This project is the first to target in restoring the integrity of those brain blood vessels in order to reverse diabetes-associated dementia.
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    Funded Activity

    Fall Prevention And Physical Activity Promotion For Older Adults: Cluster Trial Of Effectiveness And Cost-effectiveness

    Funder
    National Health and Medical Research Council
    Funding Amount
    $1,291,950.00
    Summary
    This cluster randomised controlled trial will establish the impact on physical activity and falls of an intervention program that targets both physical activity and falls using assessment, advice and health coaching. The trial will involve 60 established groups of older people, recruited from local chapters of community organisations including Probus, the Older Women’s Network, registered clubs and church groups (estimated average group size of 10; total n = 600).
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