Testing theoretical models of age and disease related changes to inform prevention. Pathological brain changes associated with future cognitive decline become detectable in the 40s or earlier. Yet little is known about what constitutes normal brain ageing in mid-life. Using a number of neuroimaging and epidemiological techniques this project will scrutinise brain and cognitive ageing in middle-age and their significance.
Social relations and social engagement in older adulthood: implications for health, well being and cognition. This project will examine the nature of changes in peoples' social networks that occur with age, and the effects of these changes on health and well being in later life. The project will use information collected from several ongoing Australian studies of ageing, and will have important implications for social policy in Australia.
Sino-Australian neurogenetics initiative. This project will undertake large population studies to identify genes that are associated with motor neuron disease, schizophrenia and intracranial haemorrhage. The project will determine genetic markers, aid development of diagnostic tools and identify new therapeutic targets for these common heritable neurological diseases.
Social outcomes, behaviour and emotional well-being of adults with autism. It is recognised that autism results in substantial life-long disability. Severe emotional and behavioural problems are likely to be a key factor in precluding adults with autism from work, independent living, social contact, and undermine their quality of life, thus increasing support needs. This project aims to address a major gap in our current knowledge - the association between severe emotional and behavioural proble ....Social outcomes, behaviour and emotional well-being of adults with autism. It is recognised that autism results in substantial life-long disability. Severe emotional and behavioural problems are likely to be a key factor in precluding adults with autism from work, independent living, social contact, and undermine their quality of life, thus increasing support needs. This project aims to address a major gap in our current knowledge - the association between severe emotional and behavioural problems in adults with autism and social outcomes. Identification of markers of adult outcomes aims to lead to an improved understanding of the pathways to better social outcomes, facilitating the development of specific interventions to provide much needed improvements in outcomes for adults with autism.Read moreRead less
The role of oxytocin in attachment patterns and socio-emotional development. The role of oxytocin in attachment patterns and socio-emotional development. This project aims to better understand how oxytocin mediates links between maternal sensitivity and attachment and child socio-emotional outcomes. The child's emotional health is the most powerful childhood predictor of adult life satisfaction, and evidence points to the pivotal role of the oxytocin system on mother-child interactions and attac ....The role of oxytocin in attachment patterns and socio-emotional development. The role of oxytocin in attachment patterns and socio-emotional development. This project aims to better understand how oxytocin mediates links between maternal sensitivity and attachment and child socio-emotional outcomes. The child's emotional health is the most powerful childhood predictor of adult life satisfaction, and evidence points to the pivotal role of the oxytocin system on mother-child interactions and attachment representations that affect children's socio-emotional development. As a longitudinal study of oxytocin function in mother-child dyads, it examines how genetic, epigenetic and parenting factors determine socio-emotional and temperamental outcomes.Read moreRead less
The NSW child development study. Research shows that a child's development predicts health and social outcomes later in life. This Australian project will be the first to identify risk and protective factors associated with these outcomes in 87,000 children from birth to 10 years. The results will help inform governments to improve our children's health and educational achievements.
A longitudinal study into the development of personal vulnerabilities and well-being in adolescence. Character strengths such as empathy and emotion management skills are potentially teachable and help prevent an adolescent from experiencing difficulties in social, emotional, and academic adjustment. This longitudinal study examines the temperament and environmental factors that promote character strengths in adolescents.
Into the thirties: Persistence and social consequences of risky drinking. The aim of this project is to investigate the social contexts, roles and consequences of problematic alcohol use in adults aged 30, using long term longitudinal resources able to observe the development and corollary of alcohol use over time. It is posited that such drinkers entering their third decade of life persist in levels of problematic alcohol use typically associated with younger ages and that this leads to social ....Into the thirties: Persistence and social consequences of risky drinking. The aim of this project is to investigate the social contexts, roles and consequences of problematic alcohol use in adults aged 30, using long term longitudinal resources able to observe the development and corollary of alcohol use over time. It is posited that such drinkers entering their third decade of life persist in levels of problematic alcohol use typically associated with younger ages and that this leads to social consequences, such as gender specific risks, relationship conflicts and more severe long term effects. Outcomes from this project are expected to inform the generation of relevant prevention and intervention strategies aimed to address problem drinking in adult Australians.Read moreRead less
Plasma protein profiles in normal brain ageing and early stages of dementia. Brain changes related to ageing and dementia are associated with altered proteins that can be detected in the blood. This project will examine blood samples from a number of well-characterised ageing cohorts to discover proteins that may serve as potential markers of brain ageing and the early stages of dementia.
School non-attendance in students with intellectual disability. This project aims to develop a better understanding of school non-attendance among children and adolescents with intellectual disability. School non-attendance is a major societal problem – school outcomes are affected by high rates of school non-attendance – and a current national and international priority. In particular, school non-attendance in students with intellectual disability is a common but poorly understood problem. This ....School non-attendance in students with intellectual disability. This project aims to develop a better understanding of school non-attendance among children and adolescents with intellectual disability. School non-attendance is a major societal problem – school outcomes are affected by high rates of school non-attendance – and a current national and international priority. In particular, school non-attendance in students with intellectual disability is a common but poorly understood problem. This project aims to understand the types and rates of school non-attendance problems in students with intellectual disability and the factors that influence non-attendance. Improved understanding of the pathways to non-attendance would facilitate the development of specific interventions to provide much-needed improvements in attendance in this disadvantaged group.Read moreRead less