How do we cancel or modify movements? This collaborative project aims to improve our understanding of how movements are rapidly cancelled, or reprogrammed, based on visual cues. Using innovative computational models, non-invasive brain stimulation and recordings of muscle activity, the project aims to elucidate how our brains anticipate the possibility of having to cancel planned actions, and how this changes as a function of healthy ageing. The outcomes are expected to assist in the design of n ....How do we cancel or modify movements? This collaborative project aims to improve our understanding of how movements are rapidly cancelled, or reprogrammed, based on visual cues. Using innovative computational models, non-invasive brain stimulation and recordings of muscle activity, the project aims to elucidate how our brains anticipate the possibility of having to cancel planned actions, and how this changes as a function of healthy ageing. The outcomes are expected to assist in the design of neuromorphic technologies that mimic human brain function. The generated knowledge may also inform future research aimed at maintaining cognitive and motor function in the ageing workforce and treating conditions in which inhibitory control is compromised. Read moreRead less
Sibling influence on development of children with autism spectrum disorder. This project aims to investigate how typically-developing siblings affect the development of children with autism spectrum disorder (ASD). ASD involves difficulties with language, executive functions and social understanding. For typically-developing children, growing up with siblings gives an advantage in these cognitive functions. Yet little is known about how having siblings’ impacts on cognitive development of childr ....Sibling influence on development of children with autism spectrum disorder. This project aims to investigate how typically-developing siblings affect the development of children with autism spectrum disorder (ASD). ASD involves difficulties with language, executive functions and social understanding. For typically-developing children, growing up with siblings gives an advantage in these cognitive functions. Yet little is known about how having siblings’ impacts on cognitive development of children with ASD. The project intends to longitudinally explore the mechanisms of sibling impact in families with and without a child with ASD. The outcomes will deepen understanding of child development, providing an evidence base for effective interventions to increase child competence and aiming ultimately to reduce the social costs of ASD.Read moreRead less
Ready, steady, go: Infant motor development and cognition. This project aims to examine the changes in and relationships between cognition and motoric abilities during infancy. The project will utilise well-established and innovative measures of memory flexibility and motor development to generate new knowledge about the complex relationship between action, perception, and cognition. The expected outcomes will provide significant benefits such as increased scientific and public knowledge on earl ....Ready, steady, go: Infant motor development and cognition. This project aims to examine the changes in and relationships between cognition and motoric abilities during infancy. The project will utilise well-established and innovative measures of memory flexibility and motor development to generate new knowledge about the complex relationship between action, perception, and cognition. The expected outcomes will provide significant benefits such as increased scientific and public knowledge on early development and an evidence base on the normal stages of infant development, relevant for health policy.Read moreRead less
Engaging the over 50s to ensure the sustainability of our blood supply. Australia faces blood shortages as our population ages and demand for blood-product derived treatments increase. Donors aged over 50 donate more regularly with fewer adverse events than younger donors, yet comprise under 24% of blood donors. This multi-method project aims to investigate how those aged over 50 understand and engage with blood donation in the context of ageing, and how their involvement can be managed to maint ....Engaging the over 50s to ensure the sustainability of our blood supply. Australia faces blood shortages as our population ages and demand for blood-product derived treatments increase. Donors aged over 50 donate more regularly with fewer adverse events than younger donors, yet comprise under 24% of blood donors. This multi-method project aims to investigate how those aged over 50 understand and engage with blood donation in the context of ageing, and how their involvement can be managed to maintain psychosocial wellbeing. This project expects to generate new knowledge in recruiting, retaining, and deferring older blood donors. Expected outcomes include tailored, validated resources that may significantly benefit Australia by effectively engaging older adults to ensure the sustainability of the blood supply.Read moreRead less
Turning back the clock on brain cell aging. This proposal aims to determine the role of fundamental epigenetic mechanisms in the process of aging and whether modulation of the epi-genome underpins an improvement in cognitive function. It combines the fields of epigenetics, neurosciences and mathematics to delineate the dynamics of DNA methylation and histone modification marking on the transcriptome during normal, healthy aging. The outcomes will provide significant new knowledge of the variable ....Turning back the clock on brain cell aging. This proposal aims to determine the role of fundamental epigenetic mechanisms in the process of aging and whether modulation of the epi-genome underpins an improvement in cognitive function. It combines the fields of epigenetics, neurosciences and mathematics to delineate the dynamics of DNA methylation and histone modification marking on the transcriptome during normal, healthy aging. The outcomes will provide significant new knowledge of the variable cognitive decline that occurs in healthy aging and why some populations age less successfully than others do. Better understanding of the impact of environmental change on the biology of aging has potential community benefits.Read moreRead less
Engaging residents and families in aged care facilities. This project aims to investigate resident and family engagement in communicating about medicines that affect the mind, emotions and behaviour, by developing and testing creative strategies in aged care facilities. This project expects to generate new knowledge about resident and family communication within a dynamic context of sociocultural, environmental and interpersonal challenges and opportunities. Expected outcomes of this project inc ....Engaging residents and families in aged care facilities. This project aims to investigate resident and family engagement in communicating about medicines that affect the mind, emotions and behaviour, by developing and testing creative strategies in aged care facilities. This project expects to generate new knowledge about resident and family communication within a dynamic context of sociocultural, environmental and interpersonal challenges and opportunities. Expected outcomes of this project include enhanced capacity to enable resident and family participation in bridging communication gaps. This should provide significant benefits, in terms of increased understandings about how and under what circumstances, medicines decision making can occur with residents and families in diverse situations.Read moreRead less