I am an epidemiologist investigating: 1) the frequency, pathogenesis, risk factors and impacts of common age-related eye disease, particularly focused on the four leading causes of blindness: age-related macular degeneration, cataract, glaucoma and diabetic retinopathy; 2) the potential for screening and clinical diagnostic value of retinal imaging and retinal vascular signs as predictors of major systemic conditions such as hypertension, diabetes and cardiovascular disease.