Immunological Changes During Pregnancy And The Impact On Viral Hepatitis Infection
Funder
National Health and Medical Research Council
Funding Amount
$353,355.00
Summary
Hepatitis B virus (HBV) can cause long term health problems particularly affecting the liver and can be passed from mother to baby. Despite the availability of a HBV vaccine babies can still become infected. During pregnancy there are changes in a woman’s immune system which may impact on HBV infection and make transmission to the baby more likely. This research aims to explore the changes in a woman’s immune system and the impact this has on risks for hepatitis and transmission to the baby.
Age-and Species-related Regulation Of Host Inflammatory Responses In Falciparum And Vivax Malaria
Funder
National Health and Medical Research Council
Funding Amount
$323,640.00
Summary
Malaria kills 1 million people every year, mostly children. The cause of death from malaria differs between children and adults, yet the reason for these differences is unknown. We have shown that in adults regulatory immune cells contribute to malaria disease complications. We want to test if these cells also worsen malaria disease in children. Understanding age-related differences in immune cell regulation will help to improve malaria treatment and aid development of effective malaria vaccines ....Malaria kills 1 million people every year, mostly children. The cause of death from malaria differs between children and adults, yet the reason for these differences is unknown. We have shown that in adults regulatory immune cells contribute to malaria disease complications. We want to test if these cells also worsen malaria disease in children. Understanding age-related differences in immune cell regulation will help to improve malaria treatment and aid development of effective malaria vaccines for adults and children.Read moreRead less