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Dual Stimulation Approach to Stem Cell Based Tissue Engineering. This Project aims to determine how human stem cells differentiate into different cell types in response to electrical and mechanical stimulation on a conductive biomaterial platform, and to use this knowledge to develop a custom built bioreactor. It expects to generate new insight into the mechanisms that control stem cell fate using innovative single cell measurements, and will deliver a bioreactor capable of using these mechanism ....Dual Stimulation Approach to Stem Cell Based Tissue Engineering. This Project aims to determine how human stem cells differentiate into different cell types in response to electrical and mechanical stimulation on a conductive biomaterial platform, and to use this knowledge to develop a custom built bioreactor. It expects to generate new insight into the mechanisms that control stem cell fate using innovative single cell measurements, and will deliver a bioreactor capable of using these mechanisms for large scale stem cell differentiation. The expected outcomes are a significant advancement in knowledge in the field of tissue engineering and more efficient methodology for patient-derived stem cell therapy. This will provide new pathways to improving stem cell therapy for tissue engineering applications.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE150101755
Funder
Australian Research Council
Funding Amount
$360,000.00
Summary
Regulation of cell reprogramming to pluripotency by complex topographies. This project aims to use nanotopography approaches to improve the efficiency of generating induced Pluripotent Stem Cells (iPSCs) by changing cell behaviour at biomaterial surfaces. The significance is that iPSCs have enormous potential in stem cell therapy, regenerative medicine, and disease-specific treatment, with the potential to replace other stem cell types. The expected outcomes are that cellular reprogramming proce ....Regulation of cell reprogramming to pluripotency by complex topographies. This project aims to use nanotopography approaches to improve the efficiency of generating induced Pluripotent Stem Cells (iPSCs) by changing cell behaviour at biomaterial surfaces. The significance is that iPSCs have enormous potential in stem cell therapy, regenerative medicine, and disease-specific treatment, with the potential to replace other stem cell types. The expected outcomes are that cellular reprogramming process for iPSCs generation will be improved and the canonical reprogramming factors might be reduced using surface nanotopographies of self-assembled colloidal crystals. The benefits are the promotion of productivity, the reduction of costs, and the application of iPSC derivatives, aimed at future clinical applications.Read moreRead less
Nanophotonics for strong absorption in extremely thin solar cells: moving beyond silicon. This project will lead to the development of extremely thin solar cells made of novel low-cost materials, which would likely reduce the cost of photovoltaic technology. If the cost of photovoltaics was sufficiently low then it could have a major impact on reducing greenhouse gas emissions and pollution in Australia and worldwide.
Photonic crystals at visible wavelengths. Three dimensional sculptured nano-structures made at a very high spatial resolution will open way to control light emission, propagation, and transmission at the visible wavelengths. Optically thin and transparent solar cells will be able to harvest light using structures.
Nano-optics and ultra-thin materials for an infrared spectrometer-on-a-chip. Aims: This project aims to advance optical nanoresonators and ultra-thin materials in the infrared spectral region. The project aims to use this knowledge to demonstrate an infrared spectrometer on a chip.
Significance: Infrared spectroscopy is a powerful method for identifying and study matter but is carried out using instruments that are generally large, heavy, power hungry and costly.
Expected outcomes: It is expec ....Nano-optics and ultra-thin materials for an infrared spectrometer-on-a-chip. Aims: This project aims to advance optical nanoresonators and ultra-thin materials in the infrared spectral region. The project aims to use this knowledge to demonstrate an infrared spectrometer on a chip.
Significance: Infrared spectroscopy is a powerful method for identifying and study matter but is carried out using instruments that are generally large, heavy, power hungry and costly.
Expected outcomes: It is expected that this project will generate knowledge that will allow dramatic reductions in the size, weight, power consumption and cost of infrared spectrometers.
Benefits: This should allow infrared spectrometers to be used in applications for which the size/weight/power consumption/cost of current approaches prevent their use.
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Defect generation in hetero-epitaxy on lattice mismatched substrates. High quality lattice mismatched semiconductor heterostructures are core enabling technologies for next generation electronic and optoelectronic devices with new functions and features such as monolithic integration, lower production costs, larger wafer size, and better system robustness. This project will generate new science on defect generation in lattice mismatched hetero-epitaxy with the aim of developing novel strategies ....Defect generation in hetero-epitaxy on lattice mismatched substrates. High quality lattice mismatched semiconductor heterostructures are core enabling technologies for next generation electronic and optoelectronic devices with new functions and features such as monolithic integration, lower production costs, larger wafer size, and better system robustness. This project will generate new science on defect generation in lattice mismatched hetero-epitaxy with the aim of developing novel strategies for their minimisation. The direct outcome will be higher quality HgCdTe materials on lattice mismatched Si or III-V substrates with defect density low enough for fabricating high performance mid-wave and long-wave infrared arrays with features of lower cost, larger array format size, and higher operating temperature.Read moreRead less
Stable Non-toxic Organic-inorganic Halide Perovskite Solar Cells. The project aims to develop next-generation organic-inorganic halide solar cells which are stable and non-toxic. Although rapid progress has been made in the emerging perovskite solar cell technology, it currently relies on lead as a key perovskite component. The elimination of lead from organic-inorganic halide perovskite solar cells would greatly increase their acceptance as an alternative thin film photovoltaic solution because ....Stable Non-toxic Organic-inorganic Halide Perovskite Solar Cells. The project aims to develop next-generation organic-inorganic halide solar cells which are stable and non-toxic. Although rapid progress has been made in the emerging perovskite solar cell technology, it currently relies on lead as a key perovskite component. The elimination of lead from organic-inorganic halide perovskite solar cells would greatly increase their acceptance as an alternative thin film photovoltaic solution because of their low cost and non-toxic nature. The dearth of lead-free perovskite solar cell demonstrations and the relatively low conversion efficiencies demonstrated understate their potential. This project plans to improve understanding of their photovoltaic enabling attributes by characterising and modelling their optical and electrical properties. It then plans to apply new fabrication methods to develop lead-free solar devices.Read moreRead less
Photochemical upconversion for third generation photovoltaic devices. Most solar cells cannot utilise infrared light, as the photons in this spectral region are not energetic enough to promote electrons across the energy threshold. This project will harvest this low energy light, and by 'gluing' the photons together in a process known as upconversion, the project will improve the light harvesting efficiencies of solar cells.
Energy resolving photodetection through extracting hot carrier photocurrent. The project will develop infrared metallic hot-electron photodetectors for energy and wavelength resolving photodetection. With the varied applications of infrared photodetectors in Australia, the project aims to establish a novel photodiode architecture that harnesses thermal energy through hot-electrons for high speed and broadband photodetection. By enabling energy resolving photodetection, the photodiode will combi ....Energy resolving photodetection through extracting hot carrier photocurrent. The project will develop infrared metallic hot-electron photodetectors for energy and wavelength resolving photodetection. With the varied applications of infrared photodetectors in Australia, the project aims to establish a novel photodiode architecture that harnesses thermal energy through hot-electrons for high speed and broadband photodetection. By enabling energy resolving photodetection, the photodiode will combine research laboratory scale capabilities into a single optical element. Advanced hot-electron absorber materials will be studied. The research outcomes have applications from telecommunications to biotechnology where photodetectors are a critical sensing component, and for metallic hot electrons utilised in photocatalysis.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE220100154
Funder
Australian Research Council
Funding Amount
$426,000.00
Summary
Engineering twisted two-dimensional materials for mid-infrared detectors. This project aims to engineer twisted two-dimensional materials and develop efficient room-temperature mid-infrared detectors that sense both the intensity and polarisation of light. This project expects to generate a cost-effective, ultra-compact, and multifunctional mid-infrared optical platform with high energy conversion efficiency towards advanced sensing and imaging systems. The anticipated goal of this project is to ....Engineering twisted two-dimensional materials for mid-infrared detectors. This project aims to engineer twisted two-dimensional materials and develop efficient room-temperature mid-infrared detectors that sense both the intensity and polarisation of light. This project expects to generate a cost-effective, ultra-compact, and multifunctional mid-infrared optical platform with high energy conversion efficiency towards advanced sensing and imaging systems. The anticipated goal of this project is to deliver high value-added devices with reduced energy consumption for the electronics and photonics industries. This should provide significant economic and environmental benefits by realising technological innovations, savings in materials and energy costs, and reduced environmental impact in advanced manufacturing.Read moreRead less