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Developing Novel Therapeutic Approaches To Treat Chronic Kidney Disease
Funder
National Health and Medical Research Council
Funding Amount
$2,173,545.00
Summary
Progression of chronic kidney disease (CKD) to endstage is characterised by inflammation and fibrosis. No current treatment effectively halts CKD progression. We are using protective immune cells to treat CKD and have invented a genetically-engineered immune cell which uses damaging inflammatory signals to switch them into protective cells which reverse inflammation and fibrosis where they occur, to prevent progression of CKD and other diseases, such as those of heart, lung and liver.
Driving Change To Improve Aboriginal And Torres Strait Islander Kidney Health
Funder
National Health and Medical Research Council
Funding Amount
$1,050,000.00
Summary
The burden of kidney disease affecting Aboriginal and Torres Strait Islander communities is devastating. Community members prioritise prevention of kidney disease, early detection and treatment to stop progression to dialysis. In remote areas, people requiring dialysis have to move away from their family and supports. This work will focus on innovative ways to address this disparity to improve care, treatment and services for Indigenous people living with kidney disease.