Identification of Biological pathways regulated by circular RNAs. Circular RNAs (circRNAs) are a, recently discovered molecule. circRNAs are highly abundant and expressed in a tissue and disease specific manner. Yet, currently the understanding of how circRNAs regulate biological processes is very poor. This project aims to use pooled shRNA libraries to screen a large panel of cell lines and systematically identify cellular activities that are regulated by circRNAs. The expected outcome of this ....Identification of Biological pathways regulated by circular RNAs. Circular RNAs (circRNAs) are a, recently discovered molecule. circRNAs are highly abundant and expressed in a tissue and disease specific manner. Yet, currently the understanding of how circRNAs regulate biological processes is very poor. This project aims to use pooled shRNA libraries to screen a large panel of cell lines and systematically identify cellular activities that are regulated by circRNAs. The expected outcome of this study will be a catalogue of functionally active circRNAs. Over the past decades, the wealth of knowledge on the function of linear mRNAs has had a significant impact on medicine and agriculture. Similarly understanding how circRNAs regulate cellular activities may have an analogous impact on humans.Read moreRead less
Personalised Learning for Per-pixel Prediction Tasks in Image Analysis. AI-assisted image segmentation & synthesis are very challenging and usually require pixel-level labelling (per-pixel prediction) that is costly to obtain. The small amount of labels makes it difficult to train an “optimal” unified model for varied data as conventional methods did. This project aims to develop a new paradigm “personalised learning” to tackle this problem, where each image could be dealt with a model tailored ....Personalised Learning for Per-pixel Prediction Tasks in Image Analysis. AI-assisted image segmentation & synthesis are very challenging and usually require pixel-level labelling (per-pixel prediction) that is costly to obtain. The small amount of labels makes it difficult to train an “optimal” unified model for varied data as conventional methods did. This project aims to develop a new paradigm “personalised learning” to tackle this problem, where each image could be dealt with a model tailored to individual characteristics. The success of this project could significantly advance the fundamental research in image analysis. Expected outcomes include new knowledge and algorithms for image analysis, which could benefit fields like biology and archaeology, where labeled images are hard to attain and scarce.Read moreRead less
Investigating a new way in which diet impacts animal biology. This project aims to investigate the importance of a new way in which diet can alter animal biology. High fat or high sugar diets increase the binding of products of metabolism to chromosomes, which can completely alter the way that DNA is packaged and read. This project will use cell culture, rodent and fly models to identify the regions of the genome that are most affected by the new process. The project will also determine whether ....Investigating a new way in which diet impacts animal biology. This project aims to investigate the importance of a new way in which diet can alter animal biology. High fat or high sugar diets increase the binding of products of metabolism to chromosomes, which can completely alter the way that DNA is packaged and read. This project will use cell culture, rodent and fly models to identify the regions of the genome that are most affected by the new process. The project will also determine whether the cell is harmed, or in fact harnesses the process to control development or metabolism. This project has implications for our understanding of the ways in which genes interact with the environment especially in times of change.Read moreRead less
Nuclear transport in stress. This project aims to provide key new insights into cell resistance to stress centred on subcellular transport in stress. Environmental stress in its various forms results in the breakdown of cellular functions such as conventional transport into and out of the host cell nucleus. This project will examine a nuclear transporter that has the ability to remain active in stress. Results will establish a platform for stress biology research by the evaluation of nuclear tra ....Nuclear transport in stress. This project aims to provide key new insights into cell resistance to stress centred on subcellular transport in stress. Environmental stress in its various forms results in the breakdown of cellular functions such as conventional transport into and out of the host cell nucleus. This project will examine a nuclear transporter that has the ability to remain active in stress. Results will establish a platform for stress biology research by the evaluation of nuclear transport in stress in cellular and in-vivo models, and its impact on cell fate. These outcomes will have broad-reaching benefits for enacting climate change responses as well as enhancing Australia’s international collaborative network and providing research training opportunities.Read moreRead less
Early career teacher induction: Supporting precarious teachers. This project aims to investigate the ways in which Australian induction policies support precariously employed early career teachers to effectively manage student classroom behaviour. This project expects to generate new knowledge of workforce development and induction experiences of early career teachers employed on casual and short-term contracts. Expected outcomes of this project include alternative policy and practice recommenda ....Early career teacher induction: Supporting precarious teachers. This project aims to investigate the ways in which Australian induction policies support precariously employed early career teachers to effectively manage student classroom behaviour. This project expects to generate new knowledge of workforce development and induction experiences of early career teachers employed on casual and short-term contracts. Expected outcomes of this project include alternative policy and practice recommendations to support the transition of insecure replacement teachers within the profession. The benefits of this research include, improving teachers’ classroom management practices; the retention of new teachers; improving teacher workforce development; and building a healthier education system. Read moreRead less
Teacher capabilities in conditions of superdiversity. The increasing diversity of students in schools presents a significant challenge for the professional education and practice of teachers. The project aims to develop an original approach to measuring teacher capabilities to respond to and engage with difference. Its expected significance is in building new knowledge about teacher workforce development to achieve education goals and social cohesion in conditions of superdiversity. The project' ....Teacher capabilities in conditions of superdiversity. The increasing diversity of students in schools presents a significant challenge for the professional education and practice of teachers. The project aims to develop an original approach to measuring teacher capabilities to respond to and engage with difference. Its expected significance is in building new knowledge about teacher workforce development to achieve education goals and social cohesion in conditions of superdiversity. The project's expected outcomes include a metric of teacher capabilities that can inform the professional education of teachers and policy settings in this country and internationally. This large-scale study should return real benefits to ensure successful education and well-being of diverse students.Read moreRead less
Equipping Australian teachers today to face AI tomorrow. Applications of Artificial Intelligence (AI) are set to transform society, including how people work and learn. Yet there is very little research about what Australian teachers need to know in order to prepare students to thrive in an AI-rich society and workforce. This study aims to construct a foundational understanding for teaching with and about AI. It will also show how to develop effective networks to empower teachers as active chang ....Equipping Australian teachers today to face AI tomorrow. Applications of Artificial Intelligence (AI) are set to transform society, including how people work and learn. Yet there is very little research about what Australian teachers need to know in order to prepare students to thrive in an AI-rich society and workforce. This study aims to construct a foundational understanding for teaching with and about AI. It will also show how to develop effective networks to empower teachers as active change agents. The expected outcomes will equip teachers with the knowledge and resources to lead the development of Australia’s future AI capability, including through enhanced classroom practices and more creative teacher networks.Read moreRead less
Feedback literacy for effective learning at university and beyond. This project aims to develop frameworks and strategies that help learners make the most of feedback across their studies and into their working lives. Using behaviour change techniques from the health and social sciences, the project expects to develop ways to support students and graduates to seek out and use feedback, and to manage their emotions throughout the feedback process. Expected outcomes of this project include evidenc ....Feedback literacy for effective learning at university and beyond. This project aims to develop frameworks and strategies that help learners make the most of feedback across their studies and into their working lives. Using behaviour change techniques from the health and social sciences, the project expects to develop ways to support students and graduates to seek out and use feedback, and to manage their emotions throughout the feedback process. Expected outcomes of this project include evidence-informed strategies that individuals and institutions can use to develop life-long capabilities to make the most of feedback. This should provide significant benefits across all sectors of Australian society, where productivity, learning and wellbeing depend on healthy and effective engagement with feedback.Read moreRead less
Enacting Climate Change Education through representing scientists’ practice. This research will work with scientists and teachers across three continents to translate contemporary climate-related research practices into a novel curriculum approach that emphasises deep science knowledge, skills, and values. It responds to a pressing national need to prepare students for a 21st century marked by complex work futures and major socio-scientific challenges related to climate change. The project will ....Enacting Climate Change Education through representing scientists’ practice. This research will work with scientists and teachers across three continents to translate contemporary climate-related research practices into a novel curriculum approach that emphasises deep science knowledge, skills, and values. It responds to a pressing national need to prepare students for a 21st century marked by complex work futures and major socio-scientific challenges related to climate change. The project will develop students’ engagement with and competencies in the sciences for fast changing work futures, and decision making and action regarding environmental challenges. It contributes to an enhanced scientific workforce and a citizenry capable of responding to complex environment-related challenges.
Read moreRead less
Supporting teachers and teaching in the age of Artificial Intelligence. This project aims to investigate teacher capabilities to respond to, and engage with, Artificial Intelligence (AI) tools in their classrooms and online teaching. This project expects to generate significant new knowledge about teacher workforce development to work productively alongside AI and other automated technologies. Expected outcomes include insights into technical, organisational and social issues surrounding the dep ....Supporting teachers and teaching in the age of Artificial Intelligence. This project aims to investigate teacher capabilities to respond to, and engage with, Artificial Intelligence (AI) tools in their classrooms and online teaching. This project expects to generate significant new knowledge about teacher workforce development to work productively alongside AI and other automated technologies. Expected outcomes include insights into technical, organisational and social issues surrounding the deployment of AI tools in schools, and the development of models of AI best practice and professional learning. This should provide significant benefits such as improved classroom outcomes and better use of technical infrastructure investment.Read moreRead less