A new generation of multi-modality biomedical image visualisations. This research will overcome the urgent and significant burden in the routine clinical visualisation of multiple-modality biomedical image data, which are complex and exquisitely detailed from the new generation of high-resolution medical imaging scanners. Together with our industry partner RPA Hospital, we will produce 3D visualisation methodologies that will simplify and revolutionise the way biomedical data are visualised, ana ....A new generation of multi-modality biomedical image visualisations. This research will overcome the urgent and significant burden in the routine clinical visualisation of multiple-modality biomedical image data, which are complex and exquisitely detailed from the new generation of high-resolution medical imaging scanners. Together with our industry partner RPA Hospital, we will produce 3D visualisation methodologies that will simplify and revolutionise the way biomedical data are visualised, analysed and interpreted by imaging specialists and disseminated to doctors and patients. Given the pivotal role that imaging plays in modern healthcare, this will improve diagnosis and assessment, and enhance Australia's leading position in the development of frontier technologies.Read moreRead less
Large scale knowledge and image based biomedical modelling and derivation of PET-CT disease maps and treatment response. The smart use of information to improve, promote and maintain good healthcare is a critical mission for our country. Cancer is a serious problem in Australian society and 1 in 4 individuals will be affected by it in their lifetime. Our research is focussed on two types of cancer - lung cancer and the lymphomas - and it will use IT in a novel way to extract important informatio ....Large scale knowledge and image based biomedical modelling and derivation of PET-CT disease maps and treatment response. The smart use of information to improve, promote and maintain good healthcare is a critical mission for our country. Cancer is a serious problem in Australian society and 1 in 4 individuals will be affected by it in their lifetime. Our research is focussed on two types of cancer - lung cancer and the lymphomas - and it will use IT in a novel way to extract important information from a very large biomedical data repository. We hope that it will improve personalised diagnosis and treatment in these cancers and provide new information on how some cancers spread and resist our usual treatments. We think our techniques will contribute to other research areas such as astronomy, agriculture, water/energy resources, and security.Read moreRead less
Information Technology Aided Diagnosis of Dementia with PET-CT Imaging. Dementia is a significant health problem and approximately 162,000 Australians currently suffer from this disease, with costs estimated at $6 billion annually in Australia and a profound effect on the lives of carers and family members. With the ageing of the Australian population, the patient number is expected to rise to 500,000 by 2040.This research will apply innovative IT approaches to develop computer assisted diagnosi ....Information Technology Aided Diagnosis of Dementia with PET-CT Imaging. Dementia is a significant health problem and approximately 162,000 Australians currently suffer from this disease, with costs estimated at $6 billion annually in Australia and a profound effect on the lives of carers and family members. With the ageing of the Australian population, the patient number is expected to rise to 500,000 by 2040.This research will apply innovative IT approaches to develop computer assisted diagnosis of early dementia, when treatment is possible, from combined functional and anatomical imaging modalities (PET-CT). This will not only add considerable value to Australia's medical imaging infrastructure and smart use of information, but will ultimately also deliver substantial benefits to our nation and community.Read moreRead less
Integrated multi-level interpretation and its applications for intelligent multimodality biomedical image navigation, retrieval and tracking. The 64- and 128-slice positron emission tomography – computed tomography (PET-CT) devices at the Royal Prince Alfred Hospital were the first in the country. These scanners, with the medical cyclotron and radiochemistry facilities, represent an investment of over A$13 million. This project will address pressing issues in optimising the utilisation of the in ....Integrated multi-level interpretation and its applications for intelligent multimodality biomedical image navigation, retrieval and tracking. The 64- and 128-slice positron emission tomography – computed tomography (PET-CT) devices at the Royal Prince Alfred Hospital were the first in the country. These scanners, with the medical cyclotron and radiochemistry facilities, represent an investment of over A$13 million. This project will address pressing issues in optimising the utilisation of the information and systems to provide better service to patients and referring clinicians. This research will add considerable value to Australia's medical imaging infrastructure and healthcare delivery; and advance scientific research in better understanding of system biology, physiology and pathology. The research outcomes will strengthen Australia’s leading position in biomedical information technology research and Australian medical imaging expertise.Read moreRead less
Med-Graphic Avatar - a comprehensive, holistic and customisable model for personal health records. Our customisable Med-Graphic Avatar will open up unprecedented access, intuitive interpretation, smart utilisation, and new understanding of massive, diverse health data, and will herald a revolution in patient-centric, holistic medical care, synergising with next generation of participatory, personalised, preventative and predictive eHealth.
Intelligent Biomedical System Modelling and Multi-modality Image Analysis to Maximize Diagnostic Information from Medical Imaging. Medical imaging is an essential part of our Australian modern health care system and plays an important role in the diagnosis, treatment planning and decision making and assessment of treatment of patients. This project aims to maximize the benefit of federal government healthcare investment through intelligent biomedical system modelling in conjunction with multi-mo ....Intelligent Biomedical System Modelling and Multi-modality Image Analysis to Maximize Diagnostic Information from Medical Imaging. Medical imaging is an essential part of our Australian modern health care system and plays an important role in the diagnosis, treatment planning and decision making and assessment of treatment of patients. This project aims to maximize the benefit of federal government healthcare investment through intelligent biomedical system modelling in conjunction with multi-modality image analysis to extract crucial additional information for accurate diagnosis and improved treatment, which will not only lead to a major scientific advancement, but also deliver significant social benefits.Read moreRead less
Escaping the concurrency trade-off: a new approach to enterprise software. Enterprise software manages the operations of all business and government organisations. Designers of this often rely on their intuition or luck, by using high-performance database facilities whose correctness is not guaranteed. This project will show designers how to use these facilities while still having the assurance that the data will not be corrupted. This will improve the quality of the data used by Australian ent ....Escaping the concurrency trade-off: a new approach to enterprise software. Enterprise software manages the operations of all business and government organisations. Designers of this often rely on their intuition or luck, by using high-performance database facilities whose correctness is not guaranteed. This project will show designers how to use these facilities while still having the assurance that the data will not be corrupted. This will improve the quality of the data used by Australian enterprises, and thus improve their operations. Australian software designers will also benefit, as they will be able to produce software that combines high performance with assurance that concurrency errors will not occur.Read moreRead less
Varying similarity metrics in indexing and retrieving high dimensional data. Many applications require varying distance metrics by putting a weight on different dimensions. Taking an example in visual information retrieval, due to the subjective nature of similarity measurements, the distance metrics can vary between different users. The main problem with k nearest neighbour (k-nn) searches using weighted metrics in a high dimensional space is whether the searches can be done efficiently, since ....Varying similarity metrics in indexing and retrieving high dimensional data. Many applications require varying distance metrics by putting a weight on different dimensions. Taking an example in visual information retrieval, due to the subjective nature of similarity measurements, the distance metrics can vary between different users. The main problem with k nearest neighbour (k-nn) searches using weighted metrics in a high dimensional space is whether the searches can be done efficiently, since in an arbitrary distance metric the intersection between the k-nn sphere and the bounding envelopes of nodes in an index tree cannot be easily calculated. This project aims to seek a novel solution. It will create a great impact on and have many applications in high dimensional visual information retrieval, instance-based learning, complex analysis, non-parametric density estimation, etc.Read moreRead less
Smart Information Use for PET-CT Quantitative Molecular Imaging. This project aims to use advanced computing algorithms to tackle
challenging problems associated with a new medical technology called
PET-CT which combines two imaging modalities in one device. While this technology is very new and has great potential in cancer and brain disorders, it also poses major challenges for information processing and transmission. We will address these challenges by developing advanced algorithms that op ....Smart Information Use for PET-CT Quantitative Molecular Imaging. This project aims to use advanced computing algorithms to tackle
challenging problems associated with a new medical technology called
PET-CT which combines two imaging modalities in one device. While this technology is very new and has great potential in cancer and brain disorders, it also poses major challenges for information processing and transmission. We will address these challenges by developing advanced algorithms that optimally extract information from PET and CT using mathematical models that correct for the various sources of inaccuracy. Our research will put Australian biomedical researchers and healthcare professionals at the forefront of advanced medical imaging technology.Read moreRead less
Application Frameworks for Collaborative Learning. We will pioneer the use of key software engineering techniques - design patterns and application frameworks - to reduce the cost and improve the quality of online collaborative learning activities. For the first time, we will combine software engineering and educational knowledge to use design patterns to describe best practice for these activities in engineering terms; we will use application frameworks to aggregate these patterns and implement ....Application Frameworks for Collaborative Learning. We will pioneer the use of key software engineering techniques - design patterns and application frameworks - to reduce the cost and improve the quality of online collaborative learning activities. For the first time, we will combine software engineering and educational knowledge to use design patterns to describe best practice for these activities in engineering terms; we will use application frameworks to aggregate these patterns and implement them as a readily usable tool. The result will be a powerful new generation of stable collaborative eLearning tools with enhanced scalability, interoperability and adaptability.Read moreRead less