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Improving The Mental Health Outcomes Of Australian Young People
Funder
National Health and Medical Research Council
Funding Amount
$437,034.00
Summary
A majority of mental health problems begin in adolescence and young adulthood, but we lack effective prevention and early intervention strategies for poor mental health in young people. My aim is to improve the prevention of mental disorders in young people, and improve treatments and service provision for young people, with a focus on Aboriginal and transgender individuals. The findings will have important implications for prevention strategies and clinical care.
Gene - Environment Interactions As Predictors Of Clinical Outcome In At Risk Mental State
Funder
National Health and Medical Research Council
Funding Amount
$1,033,620.00
Summary
The grant aims to identify the interactive genetic, clinical and environmental determinants involved in the development, severity and outcome of schizophrenia. Translation to clinical practice will be facilitated by experimental and risk assessment bioinformatics research. This will enable the (i) identification of modifiable biological and cognitive mechanisms and (ii) construction of tools which can be used for the early prediction of transition to psychotic disorder and outcome monitoring. Th ....The grant aims to identify the interactive genetic, clinical and environmental determinants involved in the development, severity and outcome of schizophrenia. Translation to clinical practice will be facilitated by experimental and risk assessment bioinformatics research. This will enable the (i) identification of modifiable biological and cognitive mechanisms and (ii) construction of tools which can be used for the early prediction of transition to psychotic disorder and outcome monitoring. This study will identify the factors that translate genetic vulnerability to schizophrenia into overt illness. The key risk factors of stress and substance use and other environmental features will be studied as part of randomised clinical trials in young people with early symptoms who are at immediate risk of schizophrenia. This study forms part of a much larger international program of research focusing on clarifying how the vulnerability to schizophrenia develops and how it can ultimately be preventedRead moreRead less
Effectiveness Of An Internet Intervention Designed To Promote Mental Health And Prevent Common Mental Disorders In Youth
Funder
National Health and Medical Research Council
Funding Amount
$123,453.00
Summary
The project tests an innovative web-based intervention designed to promote mental health and prevent common mental disorders in youth through strengthened resilience to adversity, enhanced coping skills and improved social and occupational function. Well-being, socio-occupational function and anxiety and depressive symptoms will be measured before and for six months after the intervention in participants, and compared with scores from a group who either received a live intervention or a placebo.
Antipsychotic Medication In First-episode Psychosis: An RCT To Assess The Risk-benefit Ratio
Funder
National Health and Medical Research Council
Funding Amount
$1,141,117.00
Summary
There has been an increasing emphasis on intervening early in psychotic disorders. A fundamental principle in early intervention is “to do no harm” and benefits must outweigh the risks of treatment. While antipsychotic medication is very effective and evidence-based form of treatment for positive symptoms in most first episode psychosis (FEP) patients it has risks. This study has the potential to determine whether antipsychotic medication should be the initial treatment option for FEP.
Neuroimaging In Mental Health: The Quest For Clinically Useful Biomarkers
Funder
National Health and Medical Research Council
Funding Amount
$437,034.00
Summary
To ultimately improve treatment of mental illness, this research program aims to detect robust and reliable neuroimaging markers that are associated with affective disorders by pooling data from many samples across the world. Moreover, this research aims to develop alternative biological-based classifications of mental illness in young people, and evaluate their clinical value by examining their predictive value for treatment response and disease course.
Youth-specific Change And Outcome Measures For Effective Youth Mental Health Service Delivery
Funder
National Health and Medical Research Council
Funding Amount
$1,522,563.00
Summary
Mental ill-health is the major issue facing young Australians and the Australian government has recognised this by investing in the headspace program which by 2016 will see 90 headspace centres operating across the nation. This project uses high quality research methods to establish best practice and ensure ongoing quality improvement and importantly, answer the question: “is headspace effective in addressing the mental health issues of young Australians?”
Labels Used By Young People To Describe Mental Disorders: Their Determinants And Impact On Stigma And Help-seeking.
Funder
National Health and Medical Research Council
Funding Amount
$108,234.00
Summary
When a young person first begins to experience a mental health problem, getting professional help as early as possible is recommended. However, it is unclear whether being able to label the problem correctly when they first become aware of it actually assists a young person in getting the help they need. This study will look at how over 3,000 young Australians labelled mental disorders and which labels were more likely to guide them in choosing the best kinds of professional help and treatment.
Preventive And Early Intervention Strategies In Emerging Mental Disorders In Young People
Funder
National Health and Medical Research Council
Funding Amount
$2,000,000.00
Summary
The Centre will be developed through the extension of a youth psychiatry clinical research program of international standing across Melbourne and Sydney. The CCRE will have a major impact on the growth and sustainability of clinical research expertise in youth mental health and its translation into clinical practice. Funds will be targeted specifically at two key opportunities in an evolving structure, namely the early career path for emerging young clinical researchers and the need for more inn ....The Centre will be developed through the extension of a youth psychiatry clinical research program of international standing across Melbourne and Sydney. The CCRE will have a major impact on the growth and sustainability of clinical research expertise in youth mental health and its translation into clinical practice. Funds will be targeted specifically at two key opportunities in an evolving structure, namely the early career path for emerging young clinical researchers and the need for more innovative and potent translation of clinical research into the real world of clinical practice. NHMRC CCRE funding will strengthen the ORC initiative by strategically filling gaps in early career development and training, and drive dissemination and translation of research into clinical practice across Australia.Read moreRead less