Towards Targeting The Endosome In Neurodegenerative Disease
Funder
National Health and Medical Research Council
Funding Amount
$601,959.00
Summary
Mutations and dysregulation of the SNX27-retromer protein platform are strongly linked to Alzheimer’s disease (AD) and Parkinson’s disease (PD). This research program will determine how SNX27-retromer interacts with key molecules associated with AD and PD, the outcomes of which be significantly improved understanding of how mutations in these proteins cause disease, and a necessary molecular framework for future therapeutic targeting.
ACTION - Aggression In Children: Unravelling Gene-environment Interplay To Inform Treatment
Funder
National Health and Medical Research Council
Funding Amount
$453,871.00
Summary
Aggression inflicts a huge personal, psychological and financial burden on affected individuals, their relatives, and society at large. ACTION will deliver an overarching framework that combines a thorough understanding of pathways leading to aggression with a map of current gaps, best practices on clinical, ethical, legal, and social issues.
Fostering Responsive Mental Health Systems In The Syrian Refugee Crisis
Funder
National Health and Medical Research Council
Funding Amount
$499,989.00
Summary
The current refugee crisis across Europe and the Middle East effects both individual refugees’ psychological well-being, as they face extreme stressors in their flight from their home country. In response to this crisis, this project aims to provide a framework for scaling-up the delivery and uptake of effective community-based mental health strategies to address the specific needs of refugees with mental health problems in ways that are affordable and can be delivered to millions of refugees.
A Culturally Appropriate Approach To Improve Mental Health Outcomes In Sri Lanka And China: Mental Health First Aid
Funder
National Health and Medical Research Council
Funding Amount
$1,161,042.00
Summary
Mental Health First Aid (MHFA) training has an established track record in high-income countries of improving knowledge, attitudes and behaviours in relation to people with mental health problems. However, appropriateness of the course content and implementation models in middle-income countries is unknown. This project provides a unique opportunity to develop and pilot culturally appropriate MHFA training to improve population mental health in middle-income countries.
Adolescent indigenous Australians suffer much higher rates of psychological disorder than other Australians. At present we have no evidence for any programs that reduce the risk of suicide, depression, or posttraumatic stress disorder in this population. This project will provide the first evidence of the efficacy of a indigenously-adapted form of cognitive behaviour therapy aimed to treat anxiety, depression, substance abuse, and hopelessness in Australian Aborigines.