New Synthetic Routes to the Immobilisation of Mixed Valence Transition Metal Complexes on Conducting Metal Oxides. Highly coloured, electrochemically active transition metal dyes may find application electrochromic devices, where they may switch between contrasting coloured forms through a simple redox reaction. A prerequisite is that the dye be immobilised onto a solid conducting support whilst preserving the electrochemical and optical properties of the dye found in solution. This project tack ....New Synthetic Routes to the Immobilisation of Mixed Valence Transition Metal Complexes on Conducting Metal Oxides. Highly coloured, electrochemically active transition metal dyes may find application electrochromic devices, where they may switch between contrasting coloured forms through a simple redox reaction. A prerequisite is that the dye be immobilised onto a solid conducting support whilst preserving the electrochemical and optical properties of the dye found in solution. This project tackles this problem through a combination of organic and inorganic synthesis to develop new electrochromic dyes that may be attached to mesoporous titania.Read moreRead less
Mechanistic Studies on Biologically Active Iron Chelators. The need for orally effective drugs as alternatives to invasive treatment regimens such as subcutaneous infusion is an ongoing concern in health care. This is particularly true in people suffering iron overload. In many cases this condition is present at birth and thus the administration of vital iron chelation therapy via the oral route is a much preferred option. We have unearthed a novel series of candidates for iron chelation therapy ....Mechanistic Studies on Biologically Active Iron Chelators. The need for orally effective drugs as alternatives to invasive treatment regimens such as subcutaneous infusion is an ongoing concern in health care. This is particularly true in people suffering iron overload. In many cases this condition is present at birth and thus the administration of vital iron chelation therapy via the oral route is a much preferred option. We have unearthed a novel series of candidates for iron chelation therapy (the pyridine-2-carboxaldehyde isonicotinoyl hydrazone [PCIH] analogues) which show oral activity. These chelators undergo some interesting iron catalysed oxidation chemistry and it is vital that the mechanism of this reaction be elucidated to determine whether it will be of biological significance upon administration of these compounds as iron chelators.Read moreRead less
Cooperativity in Spin Crossover Systems: Memory, Magnetism and Microporosity. Spin-crossover centres are a well known form of inorganic electronic switch for which variation of temperature, pressure and irradiation leads to a change in d-electron configuration and therefore changes to structure, colour and magnetism. Here we aim to synthesise and study a wide variety of new spin-crossover systems where cooperativitiy between centres, induced by careful supramolecular design, will lead to molecul ....Cooperativity in Spin Crossover Systems: Memory, Magnetism and Microporosity. Spin-crossover centres are a well known form of inorganic electronic switch for which variation of temperature, pressure and irradiation leads to a change in d-electron configuration and therefore changes to structure, colour and magnetism. Here we aim to synthesise and study a wide variety of new spin-crossover systems where cooperativitiy between centres, induced by careful supramolecular design, will lead to molecules and materials having memory retention, magnetic ordering and/or microporosity. The significance of these aims covers several fundamental questions in the science of electronic systems. We also identify a number of potential nanochemical switching applications for the unique systems proposed.Read moreRead less
Polynuclear Spin-Crossover Molecular Switches: Host-Guest Chemistry, Magnetism and Memory. The generation of advanced nanomaterials requires both a control of nanoscale structure and the incorporation of specific properties into that structure. This project will lead to significant new developments in this area, with the assembly of complex molecular systems containing electronic switches. The unique combination of nanoscale switching and guest-binding and/or magnetic ordering in these systems ....Polynuclear Spin-Crossover Molecular Switches: Host-Guest Chemistry, Magnetism and Memory. The generation of advanced nanomaterials requires both a control of nanoscale structure and the incorporation of specific properties into that structure. This project will lead to significant new developments in this area, with the assembly of complex molecular systems containing electronic switches. The unique combination of nanoscale switching and guest-binding and/or magnetic ordering in these systems will lead to entirely new materials properties, leading in turn to fundamental advances in the science of molecular electronics and nanomaterials. Benefits of the research are wide-ranging, and include the development of innovative new technologies for molecular sensing, molecular separations, data storage and visual displays.Read moreRead less
The Australian-Netherlands project on work and stress research. Rapid changes in the nature of work globally require critical surveillance for effects on worker well-being and productivity. Occupational health policy trends in Australia and The Netherlands support continuous monitoring of the work environment. This project therefore provides a timely opportunity structure for intellectual exchange and capacity building for Australian and Dutch work and organisational psychologists, specifically ....The Australian-Netherlands project on work and stress research. Rapid changes in the nature of work globally require critical surveillance for effects on worker well-being and productivity. Occupational health policy trends in Australia and The Netherlands support continuous monitoring of the work environment. This project therefore provides a timely opportunity structure for intellectual exchange and capacity building for Australian and Dutch work and organisational psychologists, specifically in work stress and unemployment research. Highly experienced and emerging researchers together will develop and implement projects transnationally. Outcomes will include: joint doctoral-post doctoral supervision; joint publications and grants; advanced knowledge and applications, with international policy implications for improving working life and productivity.Read moreRead less
Ditopic receptors for the cooperative binding of cations and anions. This project is concerned with the design, synthesis and investigation of new receptor molecules that are capable of simultaneously binding metal cations and anions in a cooperative fashion. The new systems are based on a macrocyclic platform which acts as the metal binding site together with side-arms incorporating functional groups that are designed to cooperatively interact with a suitable anion. Potential applications exist ....Ditopic receptors for the cooperative binding of cations and anions. This project is concerned with the design, synthesis and investigation of new receptor molecules that are capable of simultaneously binding metal cations and anions in a cooperative fashion. The new systems are based on a macrocyclic platform which acts as the metal binding site together with side-arms incorporating functional groups that are designed to cooperatively interact with a suitable anion. Potential applications exist for this category of ditopic receptors in mineral processing where the ability to extract a metal as its metal salt may lead to more efficient solvent extraction processes.Read moreRead less
In-situ solubility and speciation studies in super-critical H2O-NaCl-CO2 mixtures using synchrotron radiation. Understanding the physics and chemistry of metals in hypersaline and supercritical solutions represents a major scientific challenge with wide-ranging applications in the fields of mineral processing, economic geology, or CO2 sequestration. The advent of very bright sources of x-rays (synchrotrons) and development of spectroscopic cells that can contain corrosives samples at high pressu ....In-situ solubility and speciation studies in super-critical H2O-NaCl-CO2 mixtures using synchrotron radiation. Understanding the physics and chemistry of metals in hypersaline and supercritical solutions represents a major scientific challenge with wide-ranging applications in the fields of mineral processing, economic geology, or CO2 sequestration. The advent of very bright sources of x-rays (synchrotrons) and development of spectroscopic cells that can contain corrosives samples at high pressure and temperature allow for the first time the in-situ observation of these solutions. This project creates strong link between Australian and French scientists. By sharing the know-how developed at the European Synchrotron Research Facility, we aim to create a world-class facility at the Australian Synchrotron that will open in Melbourne in 2007.Read moreRead less
University of Queensland/Arizona State University partnership to design industrially suitable zeolite membranes for desalination. For desalination, the highest costs are organic-based membrane replacement (lasting ~1 year) and energy requirement. Functionalised zeolitic membranes are low-cost, high performing, chemically tolerant and thermally stable. New zeolite membranes in principle could perform the separation outlasting their organic counterparts, while at the same time offering major energ ....University of Queensland/Arizona State University partnership to design industrially suitable zeolite membranes for desalination. For desalination, the highest costs are organic-based membrane replacement (lasting ~1 year) and energy requirement. Functionalised zeolitic membranes are low-cost, high performing, chemically tolerant and thermally stable. New zeolite membranes in principle could perform the separation outlasting their organic counterparts, while at the same time offering major energy reductions from higher fluxes. Current zeolite membrane research for desalination however is lacking. The proposed team offers experience in bringing highly significant lab scale technologies to industrial scales. The outcomes will address mutual priorities between Australia and USA for reliable low cost supply of fresh water.Read moreRead less
Comparing racism in Australian and Canada. Surveys of racist attitudes in Australia and Canada present a unique opportunity for comparative analysis. This project will demonstrate the central influence of place and context to attitudes to and experiences of racism. International comparative assessments of racism are rare. Comparable key concepts will be agreed, e.g.: attitudes towards cultural diversity and national identity; extent and experience of racism; multicultural policies. Overall findi ....Comparing racism in Australian and Canada. Surveys of racist attitudes in Australia and Canada present a unique opportunity for comparative analysis. This project will demonstrate the central influence of place and context to attitudes to and experiences of racism. International comparative assessments of racism are rare. Comparable key concepts will be agreed, e.g.: attitudes towards cultural diversity and national identity; extent and experience of racism; multicultural policies. Overall findings and spatial variations will be compared, aiming at publication in international journals. It will strengthen a significant relationship between geographers in Sydney and Vancouver. International recognition of the Sydney-based research cluster on racism will be enhanced.Read moreRead less
High energy neutrino astrophysics together with accretion flows into black holes. Neutrinos are very weakly interacting elementary particles that are opening a new view on astrophysical objects such as supernovae and active galactic nuclei (neutrino astronomy). Studies of astrophysical neutrino production, propagation and terrestrial detection will be made. This will shed light on the astrophysics of the sources as well as probing propagation effects such as neutrino oscillations. A distinct pro ....High energy neutrino astrophysics together with accretion flows into black holes. Neutrinos are very weakly interacting elementary particles that are opening a new view on astrophysical objects such as supernovae and active galactic nuclei (neutrino astronomy). Studies of astrophysical neutrino production, propagation and terrestrial detection will be made. This will shed light on the astrophysics of the sources as well as probing propagation effects such as neutrino oscillations. A distinct programme will study a large discrepancy in the energy balance for matter accreting into a black hole. Previous work of Buzzi and Hines will be extended to investigate whether plasma wave energy carried into the black hole can explain the discrepancy. Read moreRead less