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CAM Use Among Mid-age Women: A National Mixed-methods Study Across The Urban-rural Divide
Funder
National Health and Medical Research Council
Funding Amount
$452,251.00
Summary
The aim of this project is to understand and explain why higher proportions of mid-age women in regional areas use complementary and alternative medicine (CAM) than those in urban areas of Australia. Such work will provide an evidence-base for policy and practice on this topic and the project findings will help develop CAM initiatives and programs for women’s health that are sensitive to geographical variations in community health, health practice and provision. Women are significantly more like ....The aim of this project is to understand and explain why higher proportions of mid-age women in regional areas use complementary and alternative medicine (CAM) than those in urban areas of Australia. Such work will provide an evidence-base for policy and practice on this topic and the project findings will help develop CAM initiatives and programs for women’s health that are sensitive to geographical variations in community health, health practice and provision. Women are significantly more likely to utilise CAM treatments than males and mid-age women have been found to be the highest CAM user group amongst Australian women. Researchers and practitioners have identified treatments from within CAM as potentially well-suited to dealing with a range of health problems and associated symptoms prevalent amongst mid-age women including the onset of cancer, arthritis, diabetes and asthma as well as menopause. Our previous pilot work found that mid-age women in regional areas are significantly more likely to use CAM than those in urban areas. A number of explanations as to why this is so can be or have been proposed. These include: limited access to conventional health care services in regional areas; closer working ties between non-urban general practitioners and CAM provision; dissatisfaction with conventional health care services in regional areas and stronger informal community networks in nonurban areas. Our proposed project, drawing upon a national representative sample of mid-age women will test such hypotheses and will provide findings of benefit and interest to policy makers, practitioners, consumers and all involved in women’s health and health care across urban and regional Australia.Read moreRead less
The Insulin Signalling Pathway In Normal And Gestationally Diabetic Pregnancies
Funder
National Health and Medical Research Council
Funding Amount
$319,335.00
Summary
Gestational Diabetes Mellitus (GDM), which is defined as glucose intolerance of variable severity with onset or first recognition during pregnancy, affects 5% to 8% of pregnancies, and represents more than 10,000 women annually in Australia. The overall aim of this project is to increase our understanding of the causes of gestational diabetes. In particular, the role of various inflammatory pathways in the biochemical mechanisms involved in insulin resistance associated with GDM will be examined ....Gestational Diabetes Mellitus (GDM), which is defined as glucose intolerance of variable severity with onset or first recognition during pregnancy, affects 5% to 8% of pregnancies, and represents more than 10,000 women annually in Australia. The overall aim of this project is to increase our understanding of the causes of gestational diabetes. In particular, the role of various inflammatory pathways in the biochemical mechanisms involved in insulin resistance associated with GDM will be examined, with these pathways representing novel approaches to developing agents for efficacious clinical management strategies for the management of GDM. Although major advances have been made in our understanding of the molecular mechanisms of insulin action and identification of the defects leading to insulin resistance in type 2 diabetes, there is still a paucity of data available concerning GDM. A better understanding of the regulatory pathways that mediate insulin action may lead to the identification of molecular targets for therapy. Furthermore, the clinical effectiveness of current anti-diabetic therapies to improve insulin signal transduction will be assessed. Understanding how insulin signalling is regulated will have major and important implications for the treatment of insulin resistance and obesity. As multiple pro-inflammatory cytokines may have similar effects on insulin signalling, the shared, cytokine-induced second messenger pathways may be excellent therapeutic targets for the treatment of diabetes.Read moreRead less
A national collaboration to generate new knowledge, co-design, implement, evaluate and measure individual and organisational level interventions that will address key barriers to leadership across capacity, perceived capability and credibility and cultural diversity, to successful advance women in healthcare leadership. This work is highly prioritised by partners and in a policy context.
Development Of A Serum Based Test For Aggressive Prostate Cancer.
Funder
National Health and Medical Research Council
Funding Amount
$144,950.00
Summary
Prostate cancer is relatively slow growing, taking decades to reach clinical significance. A critical phase in the progression of prostate cancer is the transformation from latent (or dormant) to aggressive tumours; hence the saying that many men die with prostate cancer, rather than of prostate cancer. We aim to develop a test utilising inhibin-activin proteins as surrogate markers of aggressive disease based on our previous studies of a significant correlation between the expression of inhibin ....Prostate cancer is relatively slow growing, taking decades to reach clinical significance. A critical phase in the progression of prostate cancer is the transformation from latent (or dormant) to aggressive tumours; hence the saying that many men die with prostate cancer, rather than of prostate cancer. We aim to develop a test utilising inhibin-activin proteins as surrogate markers of aggressive disease based on our previous studies of a significant correlation between the expression of inhibins in tissues from men with high grade prostate cancer. This study aims to validate the correlation using serum rather than a tissue based assay.Read moreRead less
Understanding The Risk Factors And Burden Of Heart Disease And Stroke For Aboriginal And Torres Strait Islander Women
Funder
National Health and Medical Research Council
Funding Amount
$86,117.00
Summary
Heart disease and stroke is the leading cause of death for Aboriginal and Torres Strait Islander people, and accounts for over one quarter in the life expectancy gap. A recent survey found that 59% of Aboriginal and Torres Strait Islander women live with heart disease or stroke. This PhD seeks to understand the risks of, and hospitalisation and mortality from heart disease and stroke in Aboriginal and Torres Strait Islander women. The project is guided by a women’s Advisory Group.