Nanoarchitectured multifunctional porous superparamagnetic nanoparticles. This project aims to develop a method for the direct detection of biomarkers based on a new class of highly porous superparamagnetic nanoparticles with peroxidase-like activity. The particles will be used as dispersible capture agents for isolating specific targets in biological samples, and electrocatalytic nanozymes for naked-eye evaluation and electrochemical detection. The project is expected to develop simple, low-cos ....Nanoarchitectured multifunctional porous superparamagnetic nanoparticles. This project aims to develop a method for the direct detection of biomarkers based on a new class of highly porous superparamagnetic nanoparticles with peroxidase-like activity. The particles will be used as dispersible capture agents for isolating specific targets in biological samples, and electrocatalytic nanozymes for naked-eye evaluation and electrochemical detection. The project is expected to develop simple, low-cost, portable devices for the analysis of exosomes and exosomal miRNA in biological samples. The future development of this technology into diagnostic devices will improve patient outcomes by enabling earlier disease diagnosis and improved monitoring of treatment.Read moreRead less
Single molecule sensing on nanopillars: Reading complex molecular circuits. This project aims to develop an entirely new nanotechnology to visualise dynamic molecular circuits in real time, and within any biological sample as small as a single cell. This project expects to generate new knowledge in the field of cell biology and sensor technology, using innovative nanofabrication and nanoscopic fluid flows to advance understanding of the emerging field of single protein molecule interactions in c ....Single molecule sensing on nanopillars: Reading complex molecular circuits. This project aims to develop an entirely new nanotechnology to visualise dynamic molecular circuits in real time, and within any biological sample as small as a single cell. This project expects to generate new knowledge in the field of cell biology and sensor technology, using innovative nanofabrication and nanoscopic fluid flows to advance understanding of the emerging field of single protein molecule interactions in cellular pathways. Expected outcomes include a universal technology platform to detect single molecules in single cells, with potential to deliver valuable intellectual property of commercial interest and economic benefit through technological advancements.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE210101666
Funder
Australian Research Council
Funding Amount
$395,588.00
Summary
Engineering nanoparticles with enhanced adhesion at the nano-bio interfaces. This project aims to develop a next-generation adhesive nanoparticle platform through in-depth understandings of nanoparticle interactions with bio-interfaces. This project expects to generate new knowledge in the multidisciplinary research field at nano-bio-interfaces by using a recently developed nano-colloidal probe technology, instructing the rational design of nanoparticles with enhanced interface adhesive properti ....Engineering nanoparticles with enhanced adhesion at the nano-bio interfaces. This project aims to develop a next-generation adhesive nanoparticle platform through in-depth understandings of nanoparticle interactions with bio-interfaces. This project expects to generate new knowledge in the multidisciplinary research field at nano-bio-interfaces by using a recently developed nano-colloidal probe technology, instructing the rational design of nanoparticles with enhanced interface adhesive properties. Expected outcomes include a family of adhesive nanoparticles designed for nanopesticide and animal feed applications, with the potential to deliver valuable intellectual property of commercial interest and economic benefit through technology advancement.Read moreRead less
Cell Membrane Coated Photonic Crystal to study Receptor-Ligand Interactions. The current gold-standard assays for examining receptor-ligand interactions require expensive and costly fluorescent or radioactive labels or proteomics processes. This project aims to develop Artificial Photonic Cells by directly coating photonic crystals with cell membranes. The Artificial Photonic Cells retain the protein receptors in their native cell membrane environment and allow for label-free monitoring of the r ....Cell Membrane Coated Photonic Crystal to study Receptor-Ligand Interactions. The current gold-standard assays for examining receptor-ligand interactions require expensive and costly fluorescent or radioactive labels or proteomics processes. This project aims to develop Artificial Photonic Cells by directly coating photonic crystals with cell membranes. The Artificial Photonic Cells retain the protein receptors in their native cell membrane environment and allow for label-free monitoring of the receptor-ligand interactions using inexpensive miniature spectrometers - radically transforming these assays. This would generate fundamental and applied knowledge of materials sciences, photonic, and biointerfaces for label-free, ultra-sensitive, and selective assays to enable future drug and diagnostics target discovery. Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE200100174
Funder
Australian Research Council
Funding Amount
$425,000.00
Summary
X-Ray Nanolithography Facility: Towards the ultimate resolution. This Project aims to address the need for precise and scalable nanoscale fabrication by establishing a synchrotron-based X-Ray Nanolithography Facility. This Project expects to generate new knowledge in the areas of advanced manufacturing and nanotechnology using an innovative approach that combines coherent lithography and coherent imaging metrology. Expected outcomes of this project include an internationally unique, nationally ....X-Ray Nanolithography Facility: Towards the ultimate resolution. This Project aims to address the need for precise and scalable nanoscale fabrication by establishing a synchrotron-based X-Ray Nanolithography Facility. This Project expects to generate new knowledge in the areas of advanced manufacturing and nanotechnology using an innovative approach that combines coherent lithography and coherent imaging metrology. Expected outcomes of this project include an internationally unique, nationally accessible capability for manufacturing at the nanoscale and for industry-driven collaborative research. This should provide significant benefits across fields that aim to harness the unique properties of engineered nanomaterials to greatly enhance the technologies required to solve global challenges.Read moreRead less
Inorganic/organic Hybrids for flexible thermoelectric generators. Flexible thermoelectric generators can directly harvest electricity from body heat, offering a new technology for wearable electronics, but their unsatisfied performance limits their applications. This project aims to design high-efficient and mechanically robust flexible thermoelectric devices based on novel hybrids with quantum dots and conducting polymers as key components. The key breakthrough is to establish unique devices wi ....Inorganic/organic Hybrids for flexible thermoelectric generators. Flexible thermoelectric generators can directly harvest electricity from body heat, offering a new technology for wearable electronics, but their unsatisfied performance limits their applications. This project aims to design high-efficient and mechanically robust flexible thermoelectric devices based on novel hybrids with quantum dots and conducting polymers as key components. The key breakthrough is to establish unique devices with record-high thermoelectric efficiency and to illustrate the underlying mechanisms for searching new-type flexible thermoelectrics. The expected outcomes will lead to innovative technology for energy conversion and advanced manufacturing and place Australia at the forefront of energy and manufacturing fields.Read moreRead less
Industrial Transformation Research Hubs - Grant ID: IH210100040
Funder
Australian Research Council
Funding Amount
$5,000,000.00
Summary
ARC RESEARCH HUB FOR CONNECTED SENSORS FOR HEALTH. This Hub aims to develop, manufacture and deploy high-tech, cyber-secure, medically-certified IoT sensors to global health markets by integrating disparate Australian capabilities into a productive end-to-end value chain. This Hub expects to position Australia at the forefront of connected health by integrating sensor science with cyber-secure data analytics, regulatory approval and certified manufacturing capabilities. Expected outcomes of this ....ARC RESEARCH HUB FOR CONNECTED SENSORS FOR HEALTH. This Hub aims to develop, manufacture and deploy high-tech, cyber-secure, medically-certified IoT sensors to global health markets by integrating disparate Australian capabilities into a productive end-to-end value chain. This Hub expects to position Australia at the forefront of connected health by integrating sensor science with cyber-secure data analytics, regulatory approval and certified manufacturing capabilities. Expected outcomes of this Hub include advanced manufacturing capacity for connected sensors, strategic partnerships and commercialisation skills to translate sensors research to create economic benefits such as jobs and locally-made products for domestic and export markets, as well as improving the health of Australians.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE200100032
Funder
Australian Research Council
Funding Amount
$600,000.00
Summary
Advanced Multifunctional Electro-Opto-Magneto-Mechanical Analysis Platform. This project aims to build an advanced multi-functional Electro-Opto-Magneto-Mechanical analysis platform for characterizing nanomaterials and micro-/nano-scale devices. This platform expects to provide rich and unique characterization capabilities (electrical, optical, magnetic and mechanical) for hybrid devices with low temperature and high vacuum environment. The expected outcomes include multidisciplinary research co ....Advanced Multifunctional Electro-Opto-Magneto-Mechanical Analysis Platform. This project aims to build an advanced multi-functional Electro-Opto-Magneto-Mechanical analysis platform for characterizing nanomaterials and micro-/nano-scale devices. This platform expects to provide rich and unique characterization capabilities (electrical, optical, magnetic and mechanical) for hybrid devices with low temperature and high vacuum environment. The expected outcomes include multidisciplinary research collaborations and a wide range of next-generation technologies including non-invasive medical instruments, wearable devices, communication, quantum information systems and energy storage solutions. This should enable local design and construction of hybrid devices and advance the growth of local high-technology industries.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE210100848
Funder
Australian Research Council
Funding Amount
$437,299.00
Summary
Quantum control of sound with light. This project aims to build the first photonic architecture capable of controlling the quantum properties of acoustic waves travelling in crystalline materials and quantum fluids. This level of control is expected to herald new capabilities in sensing applications, quantum information and quantum computing. The project seeks to develop a silicon-based photonic platform that enables the preparation of non-classical states of sound within superfluid helium. This ....Quantum control of sound with light. This project aims to build the first photonic architecture capable of controlling the quantum properties of acoustic waves travelling in crystalline materials and quantum fluids. This level of control is expected to herald new capabilities in sensing applications, quantum information and quantum computing. The project seeks to develop a silicon-based photonic platform that enables the preparation of non-classical states of sound within superfluid helium. This new platform will also be used to develop an ultra-compact silicon-chip based laser. The project outcomes should provide a deeper understanding of quantum fluids and quantum mechanics, and enable the realisation of new quantum technologies with substantial commercialisation potential.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE190100318
Funder
Australian Research Council
Funding Amount
$368,554.00
Summary
Superfluid optomechanics with quantised vortices. This project aims to develop new technologies to probe and control the flow of superfluid helium at size-scales never before possible. Superfluid helium is the only quantum liquid, characterised by flow without dissipation and quantised vortices. Leveraging the techniques of cavity optomechanics, this project aims to demonstrate control of superfluid helium properties at the quantum level, including the first demonstration of laser-cooling of a l ....Superfluid optomechanics with quantised vortices. This project aims to develop new technologies to probe and control the flow of superfluid helium at size-scales never before possible. Superfluid helium is the only quantum liquid, characterised by flow without dissipation and quantised vortices. Leveraging the techniques of cavity optomechanics, this project aims to demonstrate control of superfluid helium properties at the quantum level, including the first demonstration of laser-cooling of a liquid into its quantum ground-state. The devices developed in this project will also serve as probes of unprecedented sensitivity for the study of 2D superfluid helium. The new technologies developed will have potential for broad uptake in the scientific community and generation of intellectual property and patents for quantum technology and inertial sensors.Read moreRead less